Search Results - "Nogueira Silva, Jean Jerley"
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Antileishmanial Activity and Inducible Nitric Oxide Synthase Activation by RuNO Complex
Published in Mediators of Inflammation (01-01-2016)“…Parasites of the genus Leishmania are capable of inhibiting effector functions of macrophages. These parasites have developed the adaptive ability to escape…”
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Experimental Chemotherapy in Paracoccidioidomycosis Using Ruthenium NO Donor
Published in Mycopathologia (1975) (01-08-2011)“…Paracoccidioidomycosis (PCM) is a granulomatous disease caused by a dimorphic fungus, Paracoccidioides brasiliensis (Pb) . To determine the influence of nitric…”
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The effects of nitric oxide on the immune response during giardiasis
Published in The Brazilian journal of infectious diseases (01-11-2010)“…Nitric oxide (NO) is a free radical synthesized from L-arginine by different isoforms NO-synthases. NO possesses multiple and complex biological functions. NO…”
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Nitric oxide and Brazilian propolis combined accelerates tissue repair by modulating cell migration, cytokine production and collagen deposition in experimental leishmaniasis
Published in PloS one (14-05-2015)“…The fact that drugs currently used in the treatment of Leishmania are highly toxic and associated with acquired resistance has promoted the search for new…”
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The effects of nitric oxide on the immune response during giardiasis
Published in The Brazilian journal of infectious diseases (01-12-2010)“…Nitric oxide (NO) is a free radical synthesized from L-arginine by different isoforms NO-synthases. NO possesses multiple and complex biological functions. NO…”
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Novel ruthenium complexes as potential drugs for Chagas's disease: enzyme inhibition and in vitro/in vivo trypanocidal activity
Published in British journal of pharmacology (01-05-2010)“…Background and purpose: The discovery of the pharmacological functions of nitric oxide has led to the development of NO donor compounds as therapeutic agents…”
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Complexation of the anti-Trypanosoma cruzi Drug Benznidazole Improves Solubility and Efficacy
Published in Journal of medicinal chemistry (24-07-2008)“…The ruthenium complex, trans-[Ru(Bz)(NH3)4SO2](CF3SO3)2 1, Bz = benznidazole (N-benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide), is more hydrosoluble and more…”
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Nitric Oxide Donors with Therapeutic Strategic in Experimental Schistossomiasis Mansoni
Published in American journal of immunology (2014)“…Schistosomiasis, an immune disease, remains a major public health problem in endemic area. To determine the influence of Nitric Oxide (NO) on this disease, the…”
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