Search Results - "Nogueira Machado, José Augusto"
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Clinical and immunological allergy assessment in cancer patients
Published in Scientific reports (13-09-2021)“…Cancer is associated with immunodeficiency, while allergies result from immune system hyperactivity mediated by cytokines and immunoglobulins. The purpose of…”
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role of L-arginine-nitric oxide pathway in bacterial translocation
Published in Amino acids (01-11-2013)“…This study investigated the nitric oxide (NO) role as a mediator of arginine on bacterial translocation (BT) and gut damage in mice after intestinal…”
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Cellular death, reactive oxygen species (ROS) and diabetic complications
Published in Cell death & disease (25-01-2018)“…Chronic or intermittent hyperglycemia is associated with the development of diabetic complications. Several signaling pathways can be altered by having…”
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Antioxidant effects of resveratrol in granulocytes from multiple sclerosis patients
Published in Exploration of neuroscience (03-09-2024)“…Aim: Neuroinflammation is a characteristic of multiple sclerosis (MS). Resveratrol (RSV) has potent antioxidant properties and has emerged as a promising…”
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Effects of immunotherapy induction on outcome and graft survival of kidney-transplanted patients with different immunological risk of rejection
Published in BMC nephrology (13-08-2019)“…In kidney transplantation, immunotherapy with thymoglobulin (rATG) has been used to down-regulate the patient immune system. rATG is a powerful immunobiologic…”
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MICRO-CONTROLLED THERMAL STIMULATOR FOR DETECTING FINE FIBER CHANGES IN PATIENTS WITH DIABETES MELLITUS: A DIAGNOSTIC ACCURACY STUDY
Published in Primary care diabetes (01-06-2021)“…•Diabetic neuropathy can lead infection or amputation.•MTS was 97.6% sensitivity, 90% specificity for detect fine fiber changes.•MTS is effective for assessing…”
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Is Galanin a Promising Therapeutic Resource for Neural and Nonneural Diseases?
Published in Current drug targets (01-01-2020)“…Galanin (GAL) constitutes a family of neuropeptides composed of four peptides: (i) galanin (GAL), (ii) galanin-message associated peptide (GAMP), (iii)…”
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Overexpression of mTOR in Leukocytes from ALS8 Patients
Published in Current neuropharmacology (01-01-2023)“…Background: The mutated VAPBP56S (vesicle B associated membrane protein – P56S) protein has been described in a Brazilian family and classified as Amyotrophic…”
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The role of oxidative stress in the aging process
Published in TheScientificWorld (01-01-2010)“…The aging of organisms is characterized by a gradual functional decline of all organ systems. An appropriate theory must explain four main characteristics of…”
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Edaravone Inhibits the Production of Reactive Oxygen Species in Phagocytosis- and PKC-Stimulated Granulocytes from Multiple Sclerosis Patients Edaravone Modulate Oxidative Stress in Multiple Sclerosis
Published in Journal of central nervous system disease (01-04-2022)“…Background Oxidative stress is associated with the pathogenesis of MS. Edaravone (EDV) has been proposed as a therapeutic resource for central nervous system…”
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β-Carotene, α-tocopherol and ascorbic acid: differential profile of antioxidant, inflammatory status and regulation of gene expression in human mononuclear cells of diabetic donors
Published in Diabetes/metabolism research and reviews (01-11-2013)“…Background Diabetic patients are exposed to increased oxidative stress due to several mechanisms, mainly hyperglycaemia. Pathological processes, such as those…”
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From hyperglycemia to AGE-RAGE interaction on the cell surface: a dangerous metabolic route for diabetic patients
Published in Expert opinion on therapeutic targets (01-07-2008)“…Diabetes mellitus constitutes a serious public health problem. Recent advances in therapies are unable to control its vascular complications. New medications…”
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Ascorbic acid, alpha-tocopherol, and beta-carotene reduce oxidative stress and proinflammatory cytokines in mononuclear cells of Alzheimer's disease patients
Published in Nutritional neuroscience (01-11-2012)“…Objectives The in vitro effect of a vitamin complex in generating and reducing oxidative species in peripheral blood mononuclear cells (PBMNC) and plasma of…”
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Pretreatment With Citrulline Improves Gut Barrier After Intestinal Obstruction in Mice
Published in JPEN. Journal of parenteral and enteral nutrition (01-01-2012)“…Background: Citrulline has been shown to be an important marker of gut function, regulator of protein metabolism, and precursor of arginine. The authors…”
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HMGB1, TLR and RAGE: a functional tripod that leads to diabetic inflammation
Published in Expert opinion on therapeutic targets (01-08-2011)“…Despite advances in treatment of diabetes mellitus, its prevalence continues to rise globally. Medications available are unable to control the vascular…”
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Role PKA and p38 MAPK on ROS production in neutrophil age-related: Lack of IL-10 effect in older subjects
Published in Mechanisms of ageing and development (01-09-2009)“…There is a large increase in the number of elderly people in modern societies. This demographic phenomenon has been paralleled by an epidemic of chronic…”
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Oxidative stress and interleukin-6 secretion during the progression of type 1 diabetes
Published in Arquivos brasileiros de endocrinologia e metabologia (01-10-2012)“…To evaluate inflammatory, oxidizing, and reducing responses during the progression of type 1 diabetes mellitus (T1DM) in patients without chronic…”
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The Production of Nitric Oxide, IL-6, and TNF-Alpha in Palmitate-Stimulated PBMNCs Is Enhanced through Hyperglycemia in Diabetes
Published in Oxidative medicine and cellular longevity (01-01-2014)“…We examined nitric oxide (NO), IL-6, and TNF- α secretion from cultured palmitate-stimulated PBMNCs or in the plasma from type 2 diabetes mellitus (T2MD)…”
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Effect of Gamma Radiation on the Activity of Hemocytes and on the Course of Schistosoma mansoni Infection in Resistant Biomphalaria tenagophila Snails
Published in Memórias do Instituto Oswaldo Cruz (01-01-2003)“…High doses of gamma radiation (10 Krad) in Biomphalaria tenagophila snails (Taim strain), which have been found to be resistant to Schistosoma mansoni , were…”
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Increase of reactive oxygen (ROS) and nitrogen (RNS) species generated by phagocyting granulocytes related to age
Published in Mechanisms of ageing and development (20-10-2000)“…In this present paper the age-induced effect on reactive oxidizing species generated by oxygen (ROS) and nitrogen (RNS) was studied using human phagocyting…”
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