Search Results - "Nogueira, Fabio César Sousa"
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Prevalence and impact of sarcopenia in individuals with heart failure with reduced ejection fraction (the SARC-HF study): A prospective observational study protocol
Published in PloS one (21-03-2024)“…Sarcopenia, a clinical syndrome primarily associated with reduced muscle mass in the elderly, has a negative impact on quality of life and survival. It can…”
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Short-Term Effect of Induced Alterations in Testosterone Levels on Fasting Plasma Amino Acid Levels in Healthy Young Men
Published in Life (Basel, Switzerland) (22-11-2021)“…Long term effect of testosterone (T) deficiency impairs metabolism and is associated with muscle degradation and metabolic disease. The association seems to…”
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Proteomic signatures of brain regions affected by tau pathology in early and late stages of Alzheimer's disease
Published in Neurobiology of disease (01-10-2019)“…Alzheimer's disease (AD) is the most common neurodegenerative disorder. Depositions of amyloid β peptide (Aβ) and tau protein are among the major pathological…”
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Enzymes in the time of COVID‐19: An overview about the effects in the human body, enzyme market, and perspectives for new drugs
Published in Medicinal research reviews (01-11-2022)“…The rising pandemic caused by a coronavirus, resulted in a scientific quest to discover some effective treatments against its etiologic agent, the severe acute…”
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Colonization of intervertebral discs by Cutibacterium acnes in patients with low back pain: Protocol for an analytical study with microbiological, phenotypic, genotypic, and multiomic techniques
Published in PloS one (27-02-2023)“…Lumbar disc degeneration (LDD) and low back pain (LBP) are two conditions that are closely related. Several studies have shown Cutibacterium acnes colonization…”
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Plasma metabolome study reveals metabolic changes induced by pharmacological castration and testosterone supplementation in healthy young men
Published in Scientific reports (23-09-2022)“…Testosterone is a hormone that plays a key role in carbohydrate, fat, and protein metabolism. Testosterone deficiency is associated with multiple…”
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Pectinases Secretion by Saccharomyces cerevisiae: Optimization in Solid-State Fermentation and Identification by a Shotgun Proteomics Approach
Published in Molecules (Basel, Switzerland) (05-08-2022)“…A sequential design strategy was applied to optimize the secretion of pectinases by a Saccharomyces cerevisiae strain, from Brazilian sugarcane liquor vat, on…”
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Quantitative proteomic analysis reveals altered enzyme expression profile in Zea mays roots during the early stages of colonization by Herbaspirillum seropedicae
Published in Proteomics (Weinheim) (01-04-2021)“…The use of plant growth‐promoting bacteria as agricultural inoculants of plants should be encouraged because of their prominent role in biological nitrogen…”
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Comprehensive Quantitative Proteome Analysis of Aedes aegypti Identifies Proteins and Pathways Involved in Wolbachia pipientis and Zika Virus Interference Phenomenon
Published in Frontiers in physiology (25-02-2021)“…Zika virus (ZIKV) is a global public health emergency due to its association with microcephaly, Guillain-Barré syndrome, neuropathy, and myelitis in children…”
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Extracellular Vesicles from Bothrops jararaca Venom Are Diverse in Structure and Protein Composition and Interact with Mammalian Cells
Published in Toxins (19-11-2022)“…Snake venoms are complex cocktails of non-toxic and toxic molecules that work synergistically for the envenoming outcome. Alongside the immediate consequences,…”
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Modelling premature cardiac aging with induced pluripotent stem cells from a hutchinson-gilford Progeria Syndrome patient
Published in Frontiers in physiology (23-11-2022)“…Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder that causes accelerated aging and a high risk of cardiovascular complications. However,…”
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Chitotriosidase 1 in the cerebrospinal fluid as a putative biomarker for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) progression
Published in Frontiers in immunology (16-08-2022)“…Human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is an inflammatory neurodegenerative disease that…”
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Monitoring casbene synthase in Jatropha curcas tissues using targeted proteomics
Published in Plant methods (06-02-2021)“…Casbene synthase (CS) is responsible for the first committed step in the biosynthesis of phorbol esters (PE) in the Euphorbiaceae. PE are abundant in the seeds…”
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Proteomic analysis of urine in rats chronically exposed to fluoride
Published in Journal of biochemical and molecular toxicology (01-01-2011)“…Urine is an ideal source of materials to search for potential disease‐related biomarkers as it is produced by the affected tissues and can be easily obtained…”
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Osmotin purified from the latex of Calotropis procera: Biochemical characterization, biological activity and role in plant defense
Published in Plant physiology and biochemistry (01-07-2011)“…A protein, similar to osmotin- and thaumatin-like proteins, was purified from Calotropis procera (Ait.) R.Br latex. The isolation procedure required two cation…”
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Metabolomic profiling suggests systemic signatures of premature aging induced by Hutchinson–Gilford progeria syndrome
Published in Metabolomics (01-07-2019)“…Introduction Hutchinson-Gilford Progeria Syndrome (HGPS) is an extremely rare genetic disorder. HGPS children present a high incidence of cardiovascular…”
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Identification and recombinant expression of an antimicrobial peptide (cecropin B-like) from soybean pest Anticarsia gemmatalis
Published in The journal of venomous animals and toxins including tropical diseases (12-03-2021)“…Insects can be found in numerous diverse environments, being exposed to pathogenic organisms like fungi and bacteria. Once these pathogens cross insect…”
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Histone deacetylase inhibition disrupts the molecular signature of the glioblastoma secretome related to extracellular vesicle-associated proteins and targets RAB7a and RAB14 in vitro
Published in Biochemical and biophysical research communications (03-12-2024)“…Glioblastoma (GBM) is the most aggressive brain tumor with a poor prognosis. While Histone Deacetylase inhibitors have shown promising results in inhibiting…”
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Epigenetic Mechanisms Histone Deacetylase–Dependent Regulate the Glioblastoma Angiogenic Matrisome and Disrupt Endothelial Cell Behavior In Vitro
Published in Molecular & cellular proteomics (01-03-2024)“…Glioblastoma (GBM) is the most aggressive brain tumor and different efforts have been employed in the search for new drugs and therapeutic protocols for GBM…”
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Bacillus velezensis H2O-1 surfactin efficiently maintains its interfacial properties in extreme conditions found in post-salt and pre-salt oil reservoirs
Published in Colloids and surfaces, B, Biointerfaces (01-12-2021)“…[Display omitted] •Five surfactin homologues produced by B. velezensis H2O-1 have been identified.•Surfactin reversed 100 % of the wettability of calcite…”
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