Search Results - "Nogués Xavier"

Low Zinc Levels at Admission Associates with Poor Clinical Outcomes in SARS-CoV-2 Infection by Vogel-González, Marina, Talló-Parra, Marc, Herrera-Fernández, Víctor, Pérez-Vilaró, Gemma, Chillón, Miguel, Nogués, Xavier, Gómez-Zorrilla, Silvia, López-Montesinos, Inmaculada, Arnau-Barrés, Isabel, Sorli-Redó, Maria Luisa, Horcajada, Juan Pablo, García-Giralt, Natalia, Pascual, Julio, Díez, Juana, Vicente, Rubén, Güerri-Fernández, Robert

“…Zinc is an essential micronutrient that impacts host-pathogen interplay at infection. Zinc balances immune responses, and also has a proven direct antiviral…”
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Microindentation for in vivo measurement of bone tissue material properties in atypical femoral fracture patients and controls by Güerri‐Fernández, Roberto C, Nogués, Xavier, Quesada Gómez, José M, Torres del Pliego, Elisa, Puig, Lluís, García‐Giralt, Natalia, Yoskovitz, Guy, Mellibovsky, Leonardo, Hansma, Paul K, Díez‐Pérez, Adolfo

“…Atypical femoral fractures (AFF) associated with long‐term bisphosphonates (LTB) are a growing concern. Their etiology is unknown, but bone material properties…”
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Bone Tissue Properties Measurement by Reference Point Indentation in Glucocorticoid‐Induced Osteoporosis by Mellibovsky, Leonardo, Prieto‐Alhambra, Daniel, Mellibovsky, Fernando, Güerri‐Fernández, Roberto, Nogués, Xavier, Randall, Connor, Hansma, Paul K, Díez‐Perez, Adolfo

“…ABSTRACT Glucocorticoids, widely used in inflammatory disorders, rapidly increase bone fragility and, therefore, fracture risk. However, common bone…”
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Functional Analyses of Four CYP1A1 Missense Mutations Present in Patients with Atypical Femoral Fractures by Ugartondo, Nerea, Martínez-Gil, Núria, Esteve, Mònica, Garcia-Giralt, Natàlia, Roca-Ayats, Neus, Ovejero, Diana, Nogués, Xavier, Díez-Pérez, Adolfo, Rabionet, Raquel, Grinberg, Daniel, Balcells, Susanna

“…Osteoporosis is the most common metabolic bone disorder and nitrogen-containing bisphosphonates (BP) are a first line treatment for it. Yet, atypical femoral…”
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Genetics and Genomics of SOST : Functional Analysis of Variants and Genomic Regulation in Osteoblasts by Martínez-Gil, Núria, Roca-Ayats, Neus, Cozar, Mónica, Garcia-Giralt, Natàlia, Ovejero, Diana, Nogués, Xavier, Grinberg, Daniel, Balcells, Susanna

“…encodes the sclerostin protein, which acts as a key extracellular inhibitor of the canonical Wnt pathway in bone, playing a crucial role in skeletal…”
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Bone tissue quality in patients with monoclonal gammopathy of uncertain significance by Orduna, Guillermina, Mellibovsky, Leonardo, Abella, Eugenia, Nogués, Xavier, Granero, Roser, García-Giralt, Natalia, Pineda-Moncusí, Marta, Güerri-Fernández, Roberto, Prieto-Alhambra, Daniel, Díez-Pérez, Adolfo

“…Introduction Monoclonal gammopathy of uncertain significance (MGUS) is highly prevalent in older adults and affects bone structure, with osteoporosis and…”
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HIV infection is associated with upregulated circulating levels of the inflammaging miR-21-5p by Meseguer-Donlo, Javier, Soldado-Folgado, Jade, Du, Juan, González-Mena, Alicia, Blasco-Hernando, Fabiola, Cañas-Ruano, Esperanza, Nogués, Xavier, Knobel, Hernando, Garcia-Giralt, Natalia, Güerri-Fernández, Robert

“…HIV infection produces a chronic inflammation which leads to early aging of people living with HIV. Even though antiretroviral treatments (ART) have…”
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Increased hip fracture and mortality in chronic kidney disease individuals: The importance of competing risks by Pérez-Sáez, María José, Prieto-Alhambra, Daniel, Barrios, Clara, Crespo, Marta, Redondo, Dolores, Nogués, Xavier, Díez-Pérez, Adolfo, Pascual, Julio

“…Abstract Background Many studies have shown a correlation between chronic kidney disease (CKD) and fracture. However, increased mortality in CKD patients is a…”
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Thromboembolic, cardiovascular and overall mortality risks of aromatase inhibitors, compared with tamoxifen treatment: an outpatient-register-based retrospective cohort study by Pineda-Moncusí, Marta, Garcia-Giralt, Natalia, Diez-Perez, Adolfo, Tusquets, Ignasi, Servitja, Sonia, Albanell, Joan, Prieto-Alhambra, Daniel, Nogués, Xavier

“…Background: Tamoxifen (TAM) and aromatase inhibitor (AI) therapies have been associated with increased risk of thromboembolic and cardiovascular events,…”
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Fracture risk in type 2 diabetic patients: A clinical prediction tool based on a large population-based cohort by Martínez-Laguna, Daniel, Tebé, Cristian, Nogués, Xavier, Kassim Javaid, M, Cooper, Cyrus, Moreno, Victor, Diez-Perez, Adolfo, Collins, Gary S, Prieto-Alhambra, Daniel

“…An increased fracture risk has been described as a complication of Type 2 diabetes mellitus (T2DM). Clinical prediction models for general population have a…”
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Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density by Alonso, Nerea, Estrada, Karol, Albagha, Omar M E, Herrera, Lizbeth, Reppe, Sjur, Olstad, Ole K, Gautvik, Kaare M, Ryan, Niamh M, Evans, Kathryn L, Nielson, Carrie M, Hsu, Yi-Hsiang, Kiel, Douglas P, Markozannes, George, Ntzani, Evangelia E, Evangelou, Evangelos, Feenstra, Bjarke, Liu, Xueping, Melbye, Mads, Masi, Laura, Brandi, Maria Luisa, Riches, Philip, Daroszewska, Anna, Olmos, José Manuel, Valero, Carmen, Castillo, Jesús, Riancho, José A, Husted, Lise B, Langdahl, Bente L, Brown, Matthew A, Duncan, Emma L, Kaptoge, Stephen, Khaw, Kay-Tee, Usategui-Martín, Ricardo, Del Pino-Montes, Javier, González-Sarmiento, Rogelio, Lewis, Joshua R, Prince, Richard L, D'Amelio, Patrizia, García-Giralt, Natalia, Nogués, Xavier, Mencej-Bedrac, Simona, Marc, Janja, Wolstein, Orit, Eisman, John A, Oei, Ling, Medina-Gómez, Carolina, Schraut, Katharina E, Navarro, Pau, Wilson, James F, Davies, Gail, Starr, John, Deary, Ian, Tanaka, Toshiko, Ferrucci, Luigi, Gianfrancesco, Fernando, Gennari, Luigi, Lucas, Gavin, Elosua, Roberto, Uitterlinden, André G, Rivadeneira, Fernando, Ralston, Stuart H

“…To identify genetic determinants of susceptibility to clinical vertebral fractures, which is an important complication of osteoporosis. Here we conduct a…”
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Current situation of shared decision making in osteoporosis: A comprehensive literature review of patient decision aids and decision drivers by Nogués, Xavier, Carbonell, María Cristina, Canals, Laura, Lizán, Luis, Palacios, Santiago

“…Background and Aims Osteoporosis is a systemic skeletal disease characterized by low bone mass and microstructural deterioration of bone tissues, resulting in…”
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The FRAILMar Study Protocol: Frailty in Patients With Advanced Chronic Kidney Disease Awaiting Kidney Transplantation. A Randomized Clinical Trial of Multimodal Prehabilitation by Pérez-Sáez, María José, Morgado-Pérez, Andrea, Faura, Anna, Muñoz-Redondo, Elena, Gárriz, Miguel, Muns, Maria Dolors, Nogués, Xavier, Marco, Ester, Pascual, Julio

“…Introduction: Frailty is very frequent among patients with chronic kidney disease (CKD) who are awaiting deceased donor kidney transplantation (KT), and…”
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Comparison of Hospitalized Coronavirus Disease 2019 and Influenza Patients Requiring Supplemental Oxygen in a Cohort Study: Clinical Impact and Resource Consumption by López Montesinos, Inmaculada, Arrieta-Aldea, Itziar, Dicastillo, Aitor, Zuccarino, Flavio, Sorli, Luisa, Guerri-Fernández, Roberto, Arnau-Barrés, Isabel, Montero, Maria Milagro, Siverio-Parès, Ana, Durán, Xavier, del Mar Arenas, Maria, Arnau, Ariadna Brasé, Cañas-Ruano, Esperanza, Castañeda, Silvia, Kamber, Ignacio Domingo, Gómez-Junyent, Joan, Pelegrín, Iván, Martínez, Francisca Sánchez, Sendra, Elena, Leiro, Lucía Suaya, Villar-García, Judit, Nogués, Xavier, Grau, Santiago, Knobel, Hernando, Gomez-Zorrilla, Silvia, Horcajada, Juan Pablo

“…Abstract Background To compare clinical characteristics, outcomes, and resource consumption of patients with coronavirus disease 2019 (COVID-19) and seasonal…”
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Genetic determinants of aromatase inhibitor-related arthralgia: the B-ABLE cohort study by Garcia-Giralt, Natalia, Rodríguez-Sanz, María, Prieto-Alhambra, Daniel, Servitja, Sonia, Torres-del Pliego, Elisa, Balcells, Susana, Albanell, Joan, Grinberg, Daniel, Diez-Perez, Adolfo, Tusquets, Ignasi, Nogués, Xavier

“…A major side effect of aromatase inhibitor (AI) therapy is AI-related arthralgia (AIA), which often leads to therapy discontinuation. We aimed to identify…”
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Functional Characterization of a GGPPS Variant Identified in Atypical Femoral Fracture Patients and Delineation of the Role of GGPPS in Bone‐Relevant Cell Types by Roca‐Ayats, Neus, Ng, Pei Ying, Garcia‐Giralt, Natàlia, Falcó‐Mascaró, Maite, Cozar, Mónica, Abril, Josep Francesc, Quesada Gómez, José Manuel, Prieto‐Alhambra, Daniel, Nogués, Xavier, Dunford, James E, Russell, R Graham, Baron, Roland, Grinberg, Daniel, Balcells, Susana, Díez‐Pérez, Adolfo

“…ABSTRACT Atypical femoral fractures (AFFs) are a rare but potentially devastating event, often but not always linked to bisphosphonate (BP) therapy. The…”
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TBS and BMD at the end of AI-therapy: A prospective study of the B-ABLE cohort by María, Rodríguez-Sanz, Marta, Pineda-Moncusí, Sonia, Servitja, Natalia, Garcia-Giralt, Tamara, Martos, Ignasi, Tusquets, Maria, Martínez-García, Jaime, Rodriguez-Morera, Adolfo, Diez-Perez, Joan, Albanell, Xavier, Nogués

“…Abstract Introduction Patients with breast cancer under aromatase inhibitor (AI) treatment often develop osteoporosis and their average bone loss rate is twice…”
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Mortality in Hemodialysis Patients with COVID-19, the Effect of Paricalcitol or Calcimimetics by Arenas Jimenez, María Dolores, González-Parra, Emilio, Riera, Marta, Rincón Bello, Abraham, López-Herradón, Ana, Cao, Higini, Hurtado, Sara, Collado, Silvia, Ribera, Laura, Barbosa, Francesc, Dapena, Fabiola, Torregrosa, Vicent, Broseta, José-Jesús, Soto Montañez, Carlos, Navarro-González, Juan F, Ramos, Rosa, Bover, Jordi, Nogués-Solan, Xavier, Crespo, Marta, Dusso, Adriana S, Pascual, Julio

“…In COVID-19 patients, low serum vitamin D (VD) levels have been associated with severe acute respiratory failure and poor prognosis. In regular hemodialysis…”
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Genetic analysis of high bone mass cases from the BARCOS cohort of Spanish postmenopausal women by Sarrión, Patricia, Mellibovsky, Leonardo, Urreizti, Roser, Civit, Sergi, Cols, Neus, García-Giralt, Natàlia, Yoskovitz, Guy, Aranguren, Alvaro, Malouf, Jorge, Di Gregorio, Silvana, Río, Luís Del, Güerri, Roberto, Nogués, Xavier, Díez-Pérez, Adolfo, Grinberg, Daniel, Balcells, Susana

“…The aims of the study were to establish the prevalence of high bone mass (HBM) in a cohort of Spanish postmenopausal women (BARCOS) and to assess the…”
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Risk factors for prediction of inadequate response to antiresorptives by Díez-Pérez, Adolfo, Olmos, Jose M, Nogués, Xavier, Sosa, Manuel, Díaz-Curiel, Manuel, Pérez-Castrillón, Jose Luis, Pérez-Cano, Ramon, Muñoz-Torres, Manuel, Torrijos, Antonio, Jodar, Esteban, Del Rio, Luis, Caeiro-Rey, Jose R, Farrerons, Jordi, Vila, Joan, Arnaud, Claude, González-Macías, Jesus

“…Some patients sustain fractures while on antiresorptives. Whether this represents an inadequate response (IR) to treatment or a chance event has not been…”
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