Search Results - "Noer, Julie B"
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ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins
Published in Biochemical journal (15-05-2013)“…ADAM (a disintegrin and metalloproteinase) 12 is a metalloprotease implicated in cancer progression. ADAM12 can activate membrane-anchored proteins, such as…”
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Elucidation of Altered Pathways in Tumor‐Initiating Cells of Triple‐Negative Breast Cancer: A Useful Cell Model System for Drug Screening
Published in Stem cells (Dayton, Ohio) (01-08-2017)“…A limited number of cancer cells within a tumor are thought to have self‐renewing and tumor‐initiating capabilities that produce the remaining cancer cells in…”
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Extrachromosomal circular DNA in cancer: history, current knowledge, and methods
Published in Trends in genetics (01-07-2022)“…Extrachromosomal circular DNA (eccDNA) is a closed-circle, nuclear, nonplasmid DNA molecule found in all tested eukaryotes. eccDNA plays important roles in…”
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HLA Class II Histocompatibility Antigen γ Chain (CD74) Expression Is Associated with Immune Cell Infiltration and Favorable Outcome in Breast Cancer
Published in Cancers (08-12-2021)“…The triple-negative breast cancer (TNBC) subtype, defined as negative for ER, PgR, and HER2, is biologically more aggressive and with a poorer prognosis than…”
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ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis and increased tumor growth
Published in Journal of cell science (15-10-2013)“…Matrix metalloproteinases (MMPs), in particular MMP-2, MMP-9 and MMP-14, play a key role in various aspects of cancer pathology. Likewise, ADAMs (a disintegrin…”
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A distinct circular DNA profile intersects with proteome changes in the genotoxic stress-related hSOD1G93A model of ALS
Published in Cell & bioscience (13-09-2023)“…Abstract Background Numerous genes, including SOD1 , mutated in familial and sporadic amyotrophic lateral sclerosis (f/sALS) share a role in DNA damage and…”
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Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines
Published in BMC cancer (22-01-2016)“…Studies in taxane and/or anthracycline refractory metastatic breast cancer (mBC) patients have shown approximately 30% response rates to irinotecan. Hence, a…”
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A distinct circular DNA profile intersects with proteome changes in the genotoxic stress-related hSOD1 G93A model of ALS
Published in Cell & bioscience (01-09-2023)“…Abstract Background Numerous genes, including SOD1, mutated in familial and sporadic amyotrophic lateral sclerosis (f/sALS) share a role in DNA damage and…”
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