Search Results - "Noe, Robert A"

SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis by Jacobs, Robert T, Nare, Bakela, Wring, Stephen A, Orr, Matthew D, Chen, Daitao, Sligar, Jessica M, Jenks, Matthew X, Noe, Robert A, Bowling, Tana S, Mercer, Luke T, Rewerts, Cindy, Gaukel, Eric, Owens, Jennifer, Parham, Robin, Randolph, Ryan, Beaudet, Beth, Bacchi, Cyrus J, Yarlett, Nigel, Plattner, Jacob J, Freund, Yvonne, Ding, Charles, Akama, Tsutomu, Zhang, Y-K, Brun, Reto, Kaiser, Marcel, Scandale, Ivan, Don, Robert

“…Human African trypanosomiasis (HAT) is an important public health problem in sub-Saharan Africa, affecting hundreds of thousands of individuals. An urgent need…”
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Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis by Jacobs, Robert T, Plattner, Jacob J, Nare, Bakela, Wring, Stephen A, Chen, Daitao, Freund, Yvonne, Gaukel, Eric G, Orr, Matthew D, Perales, Joe B, Jenks, Matthew, Noe, Robert A, Sligar, Jessica M, Zhang, Yong-Kang, Bacchi, Cyrus J, Yarlett, Nigel, Don, Robert

“…Human African trypanosomiasis, caused by the kinetoplastid parasite Trypanosoma brucei, affects thousands of people across sub-Saharan Africa, and is fatal if…”
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SAR of 2-amino and 2,4-diamino pyrimidines with in vivo efficacy against Trypanosoma brucei by Perales, Joe B., Freeman, Jennifer, Bacchi, Cyrus J., Bowling, Tana, Don, Robert, Gaukel, Eric, Mercer, Luke, Moore III, Joseph A., Nare, Bakela, Nguyen, Tien M., Noe, Robert A., Randolph, Ryan, Rewerts, Cindy, Wring, Stephen A., Yarlett, Nigel, Jacobs, Robert T.

“…A series of 2,4-diaminopyrimidines was investigated and compounds were found to have in vivo efficacy against Trypanosoma brucei in an acute mouse model…”
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Novel Thiazole Based Heterocycles as Inhibitors of LFA-1/ICAM-1 Mediated Cell Adhesion by Sanfilippo, Pauline J, Jetter, Michele C, Cordova, Richard, Noe, Robert A, Chourmouzis, Erika, Lau, Catherine Y, Wang, Elizabeth

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Discovery of non-steroidal mifepristone mimetics: Pyrazoline-based PR antagonists by Jones, David G., Liang, Xi, Stewart, Eugene L., Noe, Robert A., Kallander, Lara S., Madauss, Kevin P., Williams, Shawn P., Thompson, Scott K., Gray, David W., Hoekstra, William J.

“…[Display omitted] Mifepristone is a non-selective antagonist of 3-oxosteroid receptors with both abortifacient and anti-endometriotic activities. Non-steroidal…”
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Structure-Activity Relationships for Inhibition of Type 1 and 2 Human 5.alpha.-Reductase and Human Adrenal 3.beta.-Hydroxy-.DELTA.5-steroid Dehydrogenase/3-Keto-.DELTA.5-steroid Isomerase by 6-Azaandrost-4-en-3-ones: Optimization of the C17 Substituent by Frye, Stephen V, Haffner, Curt D, Maloney, Patrick R, Hiner, Roger N, Dorsey, George F, Noe, Robert A, Unwalla, Rayomand J, Batchelor, Kenneth W, Bramson, H. Neal, Stuart, J. Darren, Schweiker, Stephanie L, Van Arnold, John, Bickett, D. Mark, Moss, Marcia L, Tian, Gaochoa, Lee, Frank W, Tippin, Timothy K, James, Michael K, Grizzle, Mary K, Long, James E, Croom, Dallas K

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SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis: e1151 by Jacobs, Robert T, Nare, Bakela, Wring, Stephen A, Orr, Matthew D, Chen, Daitao, Sligar, Jessica M, Jenks, Matthew X, Noe, Robert A, Bowling, Tana S, Mercer, Luke T, Rewerts, Cindy, Gaukel, Eric, Owens, Jennifer, Parham, Robin, Randolph, Ryan, Beaudet, Beth, Bacchi, Cyrus J, Yarlett, Nigel, Plattner, Jacob J, Freund, Yvonne, Ding, Charles, Akama, Tsutomu, Zhang, Y-K, Brun, Reto, Kaiser, Marcel, Scandale, Ivan, Don, Robert

“…Background Human African trypanosomiasis (HAT) is an important public health problem in sub-Saharan Africa, affecting hundreds of thousands of individuals. An…”
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