Search Results - "Nocentini, G."
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Metabolic pathways in immune senescence and inflammaging: Novel therapeutic strategy for chronic inflammatory lung diseases. An EAACI position paper from the Task Force for Immunopharmacology
Published in Allergy (Copenhagen) (01-05-2024)“…The accumulation of senescent cells drives inflammaging and increases morbidity of chronic inflammatory lung diseases. Immune responses are built upon dynamic…”
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L-GILZ binds p53 and MDM2 and suppresses tumor growth through p53 activation in human cancer cells
Published in Cell death and differentiation (01-01-2015)“…The transcription factor p53 regulates the expression of genes crucial for biological processes such as cell proliferation, metabolism, cell repair, senescence…”
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The first‐generation phosphodiesterase 5 inhibitors and their pharmacokinetic issue
Published in Andrology (Oxford) (01-11-2019)“…Background Erectile dysfunction (ED) is a relatively frequent disease that negatively impacts the overall quality of life, well‐being, and relationships…”
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L-GILZ binds p53 and MDM2 and suppresses tumor growth through p53 activation in human cancer cells
Published in Cell death and differentiation (29-08-2014)Get full text
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The glucocorticoid‐induced TNF receptor family‐related protein (GITR) is critical to the development of acute pancreatitis in mice
Published in British journal of pharmacology (01-03-2011)“…BACKGROUND AND PURPOSE Pancreatitis represents a life‐threatening inflammatory condition where leucocytes, cytokines and vascular endothelium contribute to the…”
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Dietary α-linolenic acid reduces COX-2 expression and induces apoptosis of hepatoma cells
Published in Journal of lipid research (01-02-2004)“…Fatty acid synthetase (FAS) is overexpressed in various tumor tissues, and its inhibition and/or malonyl-CoA accumulation have been correlated to apoptosis of…”
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GITR interacts with the pro-apoptotic protein Siva and induces apoptosis
Published in Cell death and differentiation (01-12-2002)“…CELL DEATH AND DIFFERENTIATION: (2002) 9, 1382-1384. doi:10.1038/sj.cdd.4401140…”
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Expansion of CD4+CD25-GITR+ regulatory T-cell subset in the peripheral blood of patients with primary Sjögren's syndrome: correlation with disease activity
Published in Reumatismo (11-12-2012)“…CD4+CD25high regulatory T cells (TREG) represent a suppressive T cell subset deeply involved in the modulation of immune responses and eventually in the…”
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Glucocorticoid induced TNFR-related protein (GITR) as marker of human regulatory T cells: expansion of the GITR(+)CD25⁻ cell subset in patients with systemic lupus erythematosus
Published in Reumatismo (01-07-2010)“…Regulatory T cells (T(REG)) represent a T cell subset able to modulate immune response by suppressing autoreactive T-lymphocytes. The evidence of a reduced…”
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Enhanced expression of hepatic lipogenic enzymes in an animal model of sedentariness
Published in Journal of lipid research (01-04-2003)“…The hindlimb-suspended rat was used as animal model to investigate the effects induced by immobilization of the skeletal muscle in the expression of the genes…”
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P10-12 Investigation of the effects of endocrine disruptors on T cells differentiation
Published in Toxicology letters (01-09-2022)Get full text
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P13-06: Impact of endocrine disruptors on peripheral blood mononuclear cells in vitro : sex-related effects
Published in Toxicology letters (01-09-2023)Get full text
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Identification of three novel mRNA splice variants of GITR
Published in Cell death and differentiation (01-04-2000)Get full text
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Mechanisms of the anti‐inflammatory effects of glucocorticoids: genomic and nongenomic interference with MAPK signaling pathways
Published in The FASEB journal (01-12-2012)“…Glucocorticoids (GCs) are steroid hormones produced by the adrenal gland and regulated by the hypothalamus‐pituitary‐adrenal axis. GCs mediate effects that…”
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Aberrant telomeric structures and serum markers of telomere dysfunction in healthy aging: a preliminary study
Published in Biogerontology (Dordrecht) (01-11-2024)“…Telomeres undergo a progressive shortening process as individuals age, and it has been proposed that severely shortened and dysfunctional telomeres play a role…”
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Apolipoprotein-E genotype in normal aging, age-associated memory impairment, Alzheimer's disease and vascular dementia patients
Published in Neuroscience letters (01-08-1997)“…Apolipoprotein-E (Apo-E) genotype and allele frequencies were evaluated in patients with late-onset probable Alzheimer's disease (LOAD; n=64), early-onset…”
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GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily
Published in European journal of immunology (01-04-2005)“…Glucocorticoid‐induced TNFR‐related gene (GITR; TNFRSF18), a receptor belonging to the TNFR superfamily (TNFRSF), is activated by GITRL. GITR is expressed at…”
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GITR: a modulator of immune response and inflammation
Published in Advances in experimental medicine and biology (2009)“…Glucocorticoid-Induced TNFR-Related (GITR) protein belongs to Tumor Necrosis Factor Receptor Superfamily (TNFRSF) and stimulates both the acquired and innate…”
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Frontline: GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations
Published in European journal of immunology (01-03-2004)“…GITR (glucocorticoid‐induced TNFR family related gene) is a member of the TNFR superfamily (TNFRSF) that is expressed in different cell types, including T…”
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GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations
Published in European journal of immunology (01-03-2004)“…GITR (glucocorticoid-induced TNFR family related gene) is a member of the TNFR superfamily (TNFRSF) that is expressed in different cell types, including T…”
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