Search Results - "Nobs, Samuel P."
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The development and function of lung-resident macrophages and dendritic cells
Published in Nature immunology (01-01-2015)“…The lungs hosts their own unique populations of macrophages and dendritic cells. In this Focus Review, Kopf, Schneider and Nobs discuss the development and…”
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Alveolar macrophages are essential for protection from respiratory failure and associated morbidity following influenza virus infection
Published in PLoS pathogens (01-04-2014)“…Alveolar macrophages (AM) are critical for defense against bacterial and fungal infections. However, a definitive role of AM in viral infections remains…”
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Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages
Published in Nature immunology (01-11-2014)“…Details of the ontogeny of alveolar macrophages remain unclear. Kopf and colleagues show that fetal monocytes give rise to alveolar macrophages in a manner…”
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A microbial iron fist to fight tumors
Published in Nature immunology (01-05-2024)“…The microbiome is known to affect antitumor immune responses, but how this occurs is unclear. Rhamnose-rich polysaccharides (RHP) from a commensal strain of…”
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Phages and their potential to modulate the microbiome and immunity
Published in Cellular & molecular immunology (01-04-2021)“…Bacteriophages (hence termed phages) are viruses that target bacteria and have long been considered as potential future treatments against antibiotic-resistant…”
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Complement(ing) the microbiome in infants through breastmilk
Published in Cell research (01-07-2024)Get full text
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NFIL-trating the Host Circadian Rhythm—Microbes Fine-Tune the Epithelial Clock
Published in Cell metabolism (07-11-2017)“…The diurnal activities of the intestinal microbiota and its host are closely connected, but the nature of their circadian communication pathways remains…”
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Frontline Science: Coincidental null mutation of Csf2rα in a colony of PI3Kγ−/− mice causes alveolar macrophage deficiency and fatal respiratory viral infection
Published in Journal of leukocyte biology (01-02-2017)“…PI3Ks have been identified as key signaling proteins involved in many basic biologic processes in health and disease. Transgenic animals have been essential…”
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What makes people with diabetes more susceptible to serious lung infections?
Published in Nature (London) (13-12-2023)Get full text
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Coincidental null mutation of Csf2rα in a colony of PI3Kγ-/- mice causes alveolar macrophage deficiency and fatal respiratory viral infection
Published in Journal of leukocyte biology (28-07-2016)“…PI-3-kinases have been identified as key signaling proteins involved in many basic biological processes in health and disease. Transgenic animals have been…”
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Induction of the nuclear receptor PPAR-[gamma] by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages
Published in Nature immunology (01-11-2014)“…Tissue-resident macrophages constitute heterogeneous populations with unique functions and distinct gene-expression signatures. While it has been established…”
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Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus Infection: e1004053
Published in PLoS pathogens (01-04-2014)“…Alveolar macrophages (AM) are critical for defense against bacterial and fungal infections. However, a definitive role of AM in viral infections remains…”
Get full text
Journal Article