Search Results - "Noarbe, Brenda"

Cortical cerebrovascular and metabolic perturbations in the 5xFAD mouse model of Alzheimer's disease by Jullienne, Amandine, Szu, Jenny I, Quan, Ryan, Trinh, Michelle V, Norouzi, Tannoz, Noarbe, Brenda P, Bedwell, Amanda A, Eldridge, Kierra, Persohn, Scott C, Territo, Paul R, Obenaus, Andre

“…The 5xFAD mouse is a popular model of familial Alzheimer's disease (AD) that is characterized by early beta-amyloid (Aβ) deposition and cognitive decrements…”
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Early life adversity in male mice sculpts reward circuits by Wendel, Kara M., Short, Annabel K., Noarbe, Brenda P., Haddad, Elizabeth, Palma, Anton M., Yassa, Michael A., Baram, Tallie Z., Obenaus, Andre

“…Early life adversity (ELA) comprises a wide variety of negative experiences during early life and has been linked to cognitive impairments, reduced experiences…”
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Traumatic brain injury alters the effects of class II invariant peptide (CLIP) antagonism on chronic meningeal CLIP + B cells, neuropathology, and neurobehavioral impairment in 5xFAD mice by Iannucci, Jaclyn, Dominy, Reagan, Bandopadhyay, Shreya, Arthur, E Madison, Noarbe, Brenda, Jullienne, Amandine, Krkasharyan, Margret, Tobin, Richard P, Pereverzev, Aleksandr, Beevers, Samantha, Venkatasamy, Lavanya, Souza, Karienn A, Jupiter, Daniel C, Dabney, Alan, Obenaus, Andre, Newell-Rogers, M Karen, Shapiro, Lee A

“…Traumatic brain injury (TBI) is a significant risk factor for Alzheimer's disease (AD), and accumulating evidence supports a role for adaptive immune B and T…”
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Sex-specific alterations in emotion and homeostatic neurocircuits underlying stress-induced binge eating-like behaviors by Simon, Timothy, Ontiveros-Ángel, Perla, Noarbe, Brenda, Collins, James, Obenaus, Andre, Figueroa, Johnny

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Abstract WP323: Late-Stage Degeneration Due to Middle-Cerebral Artery Occlusion Observed in White Matter Tracts and Specific Forebrain Regions in Middle-Aged Female Rats is Attenuated by mir20a-3p Treatment: A Magnetic Resonance-Diffusion Tensor Imaging and Conventional Morphometry Study by Sampath, Dayalan, Singer, Jacob, Gopalakrishnan, Balaji, Hurst, David A, Malone, Robert, Noarbe, Brenda P, Obenaus, Andre, Sohrabji, Farida

“…Abstract only Introduction: Our earlier studies show that the small non-coding RNA, mir20a-3p, is neuroprotective after stroke, and reduces sensory-motor…”
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Lifespan diffusion MRI reveals structural abnormalities in the 5xFAD model of Alzheimer’s Disease by Noarbe, Brenda P, Jullienne, Amandine, Silvola, Rebecca, Bedwell, Amanda A, Eldridge, Kierra, Speedy, Rachael, Persohn, Scott C, Territo, Paul R, Obenaus, Andre, AD, MODEL

“…Background The Model Organism Development and Evaluation for Late‐Onset Alzheimer’s Disease (MODEL‐AD) Consortium has been established to develop the next…”
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Diffusion MRI alterations coincide with memory deficits in a novel hAβKI mouse model of Alzheimer’s Disease by Jullienne, Amandine, Noarbe, Brenda P, Keiser, Ashley, Trinh, Michelle V, Pad, Rojina, Kramár, Enikö, Dong, Tri, Beardwood, Joy, Al‐Shammari, Ameer, Wood, Marcelo A, Obenaus, Andre

“…Background The Model Organism Development and Evaluation for Late‐Onset Alzheimer’s Disease (MODEL‐AD) Consortium is developing the next generation of…”
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Characterization of brain metabolism, volume, and vasculature of the 5xFAD mouse model of Alzheimer’s Disease across lifespan by Jullienne, Amandine, Szu, Jenny, Quan, Ryan, Trinh, Michelle V, Norouzi, Tannoz, Noarbe, Brenda P, Silvola, Rebecca, Bedwell, Amanda A, Eldridge, Kierra, Speedy, Rachael, Persohn, Scott C, Territo, Paul R, Obenaus, Andre

“…Background The MODEL‐AD Consortium seeks to develop the next generation of Alzheimer’s Disease models based on human data. A popular model of familial AD is…”
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Characterization of brain metabolism, volume, and vasculature of the 5xFAD mouse model of Alzheimer’s Disease across lifespan by Jullienne, Amandine, Szu, Jenny, Quan, Ryan, Trinh, Michelle V, Norouzi, Tannoz, Noarbe, Brenda P, Silvola, Rebecca, Bedwell, Amanda A, Eldridge, Kierra, Speedy, Rachael, Persohn, Scott C, Territo, Paul R, Obenaus, Andre

“…Background The MODEL‐AD Consortium seeks to develop the next generation of Alzheimer’s Disease models based on human data. A popular model of familial AD is…”
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Prophylactic evaluation of verubecestat on disease‐ and symptom‐modifying effects in 5XFAD mice by Oblak, Adrian L., Cope, Zackary A., Quinney, Sara K., Pandey, Ravi S., Biesdorf, Carla, Masters, Andi R., Onos, Kristen D., Haynes, Leslie, Keezer, Kelly J., Meyer, Jill A., Peters, Jonathan S., Persohn, Scott A., Bedwell, Amanda A., Eldridge, Kierra, Speedy, Rachael, Little, Gabriela, Williams, Sean‐Paul, Noarbe, Brenda, Obenaus, Andre, Sasner, Michael, Howell, Gareth R., Carter, Gregory W., Williams, Harriet, Lamb, Bruce T., Territo, Paul R., Sukoff Rizzo, Stacey J.

“…Introduction Alzheimer's disease (AD) is the most common form of dementia. Beta‐secretase (BACE) inhibitors have been proposed as potential therapeutic…”
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