Search Results - "Noack, Julia"
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Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
Published in Nature (London) (24-02-2022)“…The recently emerged SARS-CoV-2 Omicron variant encodes 37 amino acid substitutions in the spike protein, 15 of which are in the receptor-binding domain (RBD),…”
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Broad betacoronavirus neutralization by a stem helix-specific human antibody
Published in Science (American Association for the Advancement of Science) (03-09-2021)“…The spillovers of betacoronaviruses in humans and the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants highlight the need for…”
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Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies
Published in Nature (London) (14-10-2021)“…SARS-CoV-2 infection—which involves both cell attachment and membrane fusion—relies on the angiotensin-converting enzyme 2 (ACE2) receptor, which is…”
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Imprinted antibody responses against SARS-CoV-2 Omicron sublineages
Published in Science (American Association for the Advancement of Science) (11-11-2022)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages carry distinct spike mutations resulting in escape from antibodies induced by…”
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Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery
Published in Nature cell biology (01-11-2016)“…The endoplasmic reticulum (ER) is a site of protein biogenesis in eukaryotic cells. Perturbing ER homeostasis activates stress programs collectively called the…”
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ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies
Published in Science (American Association for the Advancement of Science) (12-08-2022)“…The coronavirus spike glycoprotein attaches to host receptors and mediates viral fusion. Using a broad screening approach, we isolated seven monoclonal…”
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How viruses hijack the ERAD tuning machinery
Published in Journal of virology (01-09-2014)“…An essential step during the intracellular life cycle of many positive-strand RNA viruses is the rearrangement of host cell membranes to generate…”
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Testing declarative memory in laboratory rats and mice using the nonconditioned social discrimination procedure
Published in Nature protocols (01-08-2011)“…Testing declarative memory in laboratory rodents can provide insights into the fundamental mechanisms underlying this type of learning and memory processing,…”
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Unconventional roles of nonlipidated LC3 in ERAD tuning and coronavirus infection
Published in Autophagy (01-10-2012)“…Secretory and membrane proteins attain their native structure in the endoplasmic reticulum (ER). Folding-defective polypeptides are selected for degradation by…”
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Different importance of the volatile and non-volatile fractions of an olfactory signature for individual social recognition in rats versus mice and short-term versus long-term memory
Published in Neurobiology of learning and memory (01-11-2010)“…► Mice and rats differ in their social memory performance. ► Mice recognize conspecifics by their volatile and non-volatile odours. ► This results in long-term…”
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Proteostasis: bad news and good news from the endoplasmic reticulum
Published in Swiss medical weekly (21-08-2014)“…The endoplasmic reticulum (ER) is an intracellular compartment dedicated to the synthesis and maturation of secretory and membrane proteins, totalling about…”
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RETRACTED: Role of the SEL1L:LC3-I Complex as an ERAD Tuning Receptor in the Mammalian ER
Published in Molecular cell (01-06-2012)“…This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been…”
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“Make way”: Pathogen exploitation of membrane traffic
Published in Current opinion in cell biology (01-08-2020)“…Intracellular pathogens have evolved numerous strategies to manipulate their host cells to survive and replicate in a hostile environment. They often exploit…”
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Erratum: Corrigendum: Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery
Published in Nature cell biology (01-01-2017)Get full text
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Special Focus Issue on Emerging Scientists and Science Communication
Published in DNA and cell biology (01-01-2022)Get more information
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Protein trafficking: RESETting proteostasis
Published in Nature chemical biology (01-11-2014)“…A recent study reveals a new cellular pathway that clears the endoplasmic reticulum of misfolded, GPI-anchored proteins at the onset of endoplasmic reticulum…”
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RESETting proteostasis
Published in Nature chemical biology (01-11-2014)“…A recent study reveals a new cellular pathway that clears the endoplasmic reticulum of misfolded, GPI-anchored proteins at the onset of endoplasmic reticulum…”
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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
Published in Nature (London) (16-07-2020)“…A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of coronavirus disease 2019…”
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Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry
Published in Science (American Association for the Advancement of Science) (28-01-2022)“…Understanding broadly neutralizing sarbecovirus antibody responses is key to developing countermeasures against SARS-CoV-2 variants and future zoonotic…”
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Neutralization, effector function and immune imprinting of Omicron variants
Published in Nature (London) (21-09-2023)“…Currently circulating SARS-CoV-2 variants have acquired convergent mutations at hot spots in the receptor-binding domain 1 (RBD) of the spike protein. The…”
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