Search Results - "Noa, M"

Treatment with the mitochondrial‐targeted antioxidant peptide SS‐31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice by Tarantini, Stefano, Valcarcel‐Ares, Noa M., Yabluchanskiy, Andriy, Fulop, Gabor A., Hertelendy, Peter, Gautam, Tripti, Farkas, Eszter, Perz, Aleksandra, Rabinovitch, Peter S., Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan

“…Summary Moment‐to‐moment adjustment of cerebral blood flow (CBF) via neurovascular coupling has an essential role in maintenance of healthy cognitive function…”
Get full text

IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging by Toth, Peter, Tarantini, Stefano, Ashpole, Nicole M., Tucsek, Zsuzsanna, Milne, Ginger L., Valcarcel‐Ares, Noa M., Menyhart, Akos, Farkas, Eszter, Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan

“…Summary Aging is associated with marked deficiency in circulating IGF‐1, which has been shown to contribute to age‐related cognitive decline. Impairment of…”
Get full text

Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype by Tarantini, Stefano, Valcarcel-Ares, M Noa, Yabluchanskiy, Andriy, Tucsek, Zsuzsanna, Hertelendy, Peter, Kiss, Tamas, Gautam, Tripti, Zhang, Xin A, Sonntag, William E, de Cabo, Rafael, Farkas, Eszter, Elliott, Michael H, Kinter, Michael T, Deak, Ferenc, Ungvari, Zoltan, Csiszar, Anna

“…Obesity has deleterious effects on cognitive function in the elderly adults. In mice, aging exacerbates obesity-induced oxidative stress, microvascular…”
Get full text

Preclinical and clinical evidence of IGF-1 as a prognostic marker and acute intervention with ischemic stroke by Hayes, Cellas A, Valcarcel-Ares, M Noa, Ashpole, Nicole M

“…Ischemic strokes are highly prevalent in the elderly population and are a leading cause of mortality and morbidity worldwide. The risk of ischemic stroke…”
Get full text

Insulin‐like growth factor 1 deficiency exacerbates hypertension‐induced cerebral microhemorrhages in mice, mimicking the aging phenotype by Tarantini, Stefano, Valcarcel‐Ares, Noa M., Yabluchanskiy, Andriy, Springo, Zsolt, Fulop, Gabor A., Ashpole, Nicole, Gautam, Tripti, Giles, Cory B., Wren, Jonathan D., Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan

“…Summary Clinical and experimental studies show that aging exacerbates hypertension‐induced cerebral microhemorrhages (CMHs), which progressively impair…”
Get full text

Genome erosion and evidence for an intracellular niche – exploring the biology of mycoplasmas in Atlantic salmon by Cheaib, B., Yang, P., Kazlauskaite, R., Lindsay, E., Heys, C., Dwyer, T., De Noia, M., Schaal, Patrick, Sloan, W., Ijaz, U.Z., Llewellyn, M.S.

“…Mycoplasmas are the smallest autonomously self-replicating life form on the planet. Members of this bacterial genus are known to parasitise a wide array of…”
Get full text

An improved water-harvesting cycle by Öhrström, Lars, Amombo Noa, Francoise M

“…Tuning metal-organic frameworks at the atomic level helps release trapped water molecules…”
Get full text

Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex by Toth, Peter, Tarantini, Stefano, Davila, Antonio, Valcarcel-Ares, M Noa, Tucsek, Zsuzsanna, Varamini, Behzad, Ballabh, Praveen, Sonntag, William E, Baur, Joseph A, Csiszar, Anna, Ungvari, Zoltan

“…Impairment of moment-to-moment adjustment of cerebral blood flow (CBF) via neurovascular coupling is thought to play a critical role in the genesis of…”
Get more information

Clarifying the complex chemistry of cobalt(II) thiocyanate‐based tests for cocaine using single‐crystal X‐ray diffraction and spectroscopic techniques by Burks, Raychelle, Öhrström, Lars, Amombo Noa, Francoise M.

“…Cobalt(II) thiocyanate‐based tests are routinely used to screen cocaine products, with the formation of a blue species interpreted as a positive response. An…”
Get full text

Photochemical Access to Substituted β‑Lactams and β‑Lactones via the Zimmerman–O’Connell–Griffin Rearrangement by Runemark, August, Martos, Mario, Nigríni, Martin, Amombo Noa, Francoise M., Öhrström, Lars, Sundén, Henrik

“…A photomediated protocol giving facile access to substituted β-lactam and β-lactones is presented. The method realizes, for the first time, the use of the…”
Get full text

Regioselective ortho halogenation of N -aryl amides and ureas via oxidative halodeboronation: harnessing boron reactivity for efficient C–halogen bond installation by Shinde, Ganesh H., Ghotekar, Ganesh S., Amombo Noa, Francoise M., Öhrström, Lars, Norrby, Per-Ola, Sundén, Henrik

“…The installation of the C–halogen bond at the ortho position of N -aryl amides and ureas represents a tool to prepare motifs that are ubiquitous in…”
Get full text

Pharmacologically-Induced Neurovascular Uncoupling is Associated with Cognitive Impairment in Mice by Tarantini, Stefano, Hertelendy, Peter, Tucsek, Zsuzsanna, Valcarcel-Ares, M Noa, Smith, Nataliya, Menyhart, Akos, Farkas, Eszter, Hodges, Erik L, Towner, Rheal, Deak, Ferenc, Sonntag, William E, Csiszar, Anna, Ungvari, Zoltan, Toth, Peter

“…There is increasing evidence that vascular risk factors, including aging, hypertension, diabetes mellitus, and obesity, promote cognitive impairment; however,…”
Get full text

The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi by Weyer, Yannick, Schwabl, Sinead I., Tang, Xuechen, Purwar, Astha, Siegmann, Konstantin, Ruepp, Angela, Dunzendorfer-Matt, Theresia, Widerin, Michael A., Niedrist, Veronika, Mutsters, Noa J. M., Tettamanti, Maria G., Weys, Sabine, Sarg, Bettina, Kremser, Leopold, Liedl, Klaus R., Schmidt, Oliver, Teis, David

“…The Golgi apparatus is essential for protein sorting, yet its quality control mechanisms are poorly understood. Here we show that the Dsc ubiquitin ligase…”
Get full text

Pyrene Functionalized Norbornadiene‐Quadricyclane Fluorescent Photoswitches: Characterization of their Spectral Properties and Application in Imaging of Amyloid Beta Plaques by Ghasemi, Shima, Shamsabadi, Monika, Olesund, Axel, Najera, Francisco, Erbs Hillers‐Bendtsen, Andreas, Edhborg, Fredrik, Aslam, Adil S., Larsson, Wera, Wang, Zhihang, Amombo Noa, Francoise M., Salthouse, Rebecca Jane, Öhrström, Lars, Hölzel, Helen, Perez‐Inestrosa, E., Mikkelsen, Kurt V., Hanrieder, Jörg, Albinsson, Bo, Dreos, Ambra, Moth‐Poulsen, Kasper

“…This study presents the synthesis and characterization of two fluorescent norbornadiene (NBD) photoswitches, each incorporating two conjugated pyrene units…”
Get full text

Caregiver strain among North American parents of children from the Autism Treatment Network Registry Call-Back Study by Lindly, Olivia J, Shui, Amy M, Stotts, Noa M, Kuhlthau, Karen A

“…Elevated caregiver strain is common and linked to poor health in parents of children with autism. Yet, little research has examined caregiver strain…”
Get full text

Chiral Lanthanum Metal–Organic Framework with Gated CO2 Sorption and Concerted Framework Flexibility by Amombo Noa, Francoise M., Grape, Erik Svensson, Åhlén, Michelle, Reinholdsson, William E., Göb, Christian R., Coudert, François-Xavier, Cheung, Ocean, Inge, A. Ken, Öhrström, Lars

“…A metal–organic framework (MOF) CTH-17 based on lanthanum­(III) and the conformationally chiral linker 1,2,3,4,5,6-hexakis­(4-carboxyphenyl)­benzene, cpb6–:…”
Get full text

Hypertension-induced synapse loss and impairment in synaptic plasticity in the mouse hippocampus mimics the aging phenotype: implications for the pathogenesis of vascular cognitive impairment by Tucsek, Zsuzsanna, Noa Valcarcel-Ares, M., Tarantini, Stefano, Yabluchanskiy, Andriy, Fülöp, Gábor, Gautam, Tripti, Orock, Albert, Csiszar, Anna, Deak, Ferenc, Ungvari, Zoltan

“…Strong epidemiological and experimental evidence indicates that hypertension has detrimental effects on the cerebral microcirculation and thereby promotes…”
Get full text

Metal–Organic Frameworks with Hexakis(4-carboxyphenyl)benzene: Extensions to Reticular Chemistry and Introducing Foldable Nets by Amombo Noa, Francoise M, Svensson Grape, Erik, Brülls, Steffen M, Cheung, Ocean, Malmberg, Per, Inge, A. Ken, McKenzie, Christine J, Mårtensson, Jerker, Öhrström, Lars

“…Nine metal–organic frameworks have been prepared with the hexagon-shaped linker 1,2,3,4,5,6-hexakis­(4-carboxyphenyl)­benzene (H6cpb) by solvothermal reactions…”
Get full text

Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells by Ungvari, Zoltan, Tucsek, Zsuzsanna, Sosnowska, Danuta, Toth, Peter, Gautam, Tripti, Podlutsky, Andrej, Csiszar, Agnes, Losonczy, Gyorgy, Valcarcel-Ares, M Noa, Sonntag, William E, Csiszar, Anna

“…Age-related impairment of angiogenesis is likely to play a central role in cerebromicrovascular rarefaction and development of vascular cognitive impairment,…”
Get full text

Hydrogenation of Carbon Dioxide to Formate by Noble Metal Catalysts Supported on a Chemically Stable Lanthanum Rod-Metal–Organic Framework by Gumbo, Maureen, Makhubela, Banothile C. E., Amombo Noa, Francoise M., Öhrström, Lars, Al-Maythalony, Bassem, Mehlana, Gift

“…The conversion of carbon dioxide to formate is of great importance for hydrogen storage as well as being a step to access an array of olefins. Herein, we have…”
Get full text