Search Results - "Noël, Gaëtane"

Identification of TP53-induced glycolysis and apoptosis regulator (TIGAR) as the phosphoglycolate-independent 2,3-bisphosphoglycerate phosphatase by Gerin, Isabelle, Noël, Gaëtane, Bolsée, Jennifer, Haumont, Olivier, Van Schaftingen, Emile, Bommer, Guido T

“…The p53-induced protein TIGAR [TP53 (tumour protein 53)-induced glycolysis and apoptosis regulator] is considered to be a F26BPase…”
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2-Keto-4-methylthiobutyrate, an intermediate in the methionine salvage pathway, is a good substrate for CtBP1 by Achouri, Younes, Noël, Gaëtane, Van Schaftingen, Emile

“…In the present work, we have studied the kinetic properties of the catalytic domain of CtBP1, a co-repressor belonging to the d-2-hydroxyacid dehydrogenase…”
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Extremely Conserved ATP- or ADP-dependent Enzymatic System for Nicotinamide Nucleotide Repair by Marbaix, Alexandre Y., Noël, Gaëtane, Detroux, Aline M., Vertommen, Didier, Van Schaftingen, Emile, Linster, Carole L.

“…The reduced forms of NAD and NADP, two major nucleotides playing a central role in metabolism, are continuously damaged by enzymatic or heat-dependent…”
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Identification of a dehydrogenase acting on D-2-hydroxyglutarate by Achouri, Younes, Noël, Gaëtane, Vertommen, Didier, Rider, Mark H, Veiga-Da-Cunha, Maria, Van Schaftingen, Emile

“…Extracts of frozen rat liver were found to catalyse the formation of 3H2O from DL-2-hydroxy[2-3H]glutarate. Three peaks of enzyme activities were observed on…”
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Identification of the gene encoding hydroxyacid-oxoacid transhydrogenase, an enzyme that metabolizes 4-hydroxybutyrate by Kardon, Tamas, Noël, Gaëtane, Vertommen, Didier, Van Schaftingen, Emile

“…To identify the sequence of hydroxyacid-oxoacid transhydrogenase (HOT), responsible for the oxidation of 4-hydroxybutyrate in mammalian tissues, we have…”
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Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia by Wiame, Elsa, Tyteca, Donatienne, Pierrot, Nathalie, Collard, François, Amyere, Mustapha, Noel, Gaëtane, Desmedt, Jonathan, Nassogne, Marie-Cécile, Vikkula, Miikka, Octave, Jean-Noël, Vincent, Marie-Françoise, Courtoy, Pierre J, Boltshauser, Eugen, van Schaftingen, Emile

“…The brain-specific compound NAA (N-acetylaspartate) occurs almost exclusively in neurons, where its concentration reaches approx. 20 mM. Its abundance is…”
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Structure of the gene mutated in glycogen storage disease type Ib by Gerin, Isabelle, Veiga-da-Cunha, Maria, Noël, Gaëtane, Van Schaftingen, Emile

“…We report the structure of the human gene encoding the putative glucose 6-phosphate translocase that is mutated in glycogen storage disease type Ib. Northern…”
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A conserved phosphatase destroys toxic glycolytic side products in mammals and yeast by Collard, François, Baldin, Francesca, Gerin, Isabelle, Bolsée, Jennifer, Noël, Gaëtane, Graff, Julie, Veiga-da-Cunha, Maria, Stroobant, Vincent, Vertommen, Didier, Houddane, Amina, Rider, Mark H, Linster, Carole L, Van Schaftingen, Emile, Bommer, Guido T

“…The glycolytic enzymes GAPDH and pyruvate kinase produce 4-phosphoerythronate and 2-phospho- L -lactate, which block metabolic flux. A newly identified…”
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A Gene Encoding a Putative FAD-Dependent L-2-Hydroxyglutarate Dehydrogenase Is Mutated in L-2-Hydroxyglutaric Aciduria by Rzem, Rim, Maria Veiga-da-Cunha, Noël, Gaëtane, Goffette, Sophie, Nassogne, Marie-Cécile, Tabarki, Brahim, Schöller, Christina, Marquardt, Thorsten, Vikkula, Miikka, van Schaftingen, Emile, Beavo, Joseph A.

“…The purpose of this study was to identify the biochemical and genetic defect in L-2-hydroxyglutaric aciduria, a neurometabolic disorder characterized by the…”
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Ethylmalonyl-CoA Decarboxylase, a New Enzyme Involved in Metabolite Proofreading by Linster, Carole L., Noël, Gaëtane, Stroobant, Vincent, Vertommen, Didier, Vincent, Marie-Françoise, Bommer, Guido T., Veiga-da-Cunha, Maria, Van Schaftingen, Emile

“…A limited number of enzymes are known that play a role analogous to DNA proofreading by eliminating non-classical metabolites formed by side activities of…”
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Characterization of the role of gamma2 R531G mutation in AMP-activated protein kinase in cardiac hypertrophy and Wolff-Parkinson-White syndrome by Davies, Joanna K, Wells, Dominic J, Liu, Ke, Whitrow, Helen R, Daniel, Tyrone D, Grignani, Robert, Lygate, Craig A, Schneider, Jürgen E, Noël, Gaëtane, Watkins, Hugh, Carling, David

“…AMP-activated protein kinase (AMPK) is the downstream component of a protein kinase cascade that plays a key role in the regulation of energy metabolism. In…”
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Novel Arguments in Favor of the Substrate-Transport Model of Glucose-6-Phosphatase by GERIN, Isabelle, NOËL, Gaëtane, VAN SCHAFTINGEN, Emile

“…Novel Arguments in Favor of the Substrate-Transport Model of Glucose-6-Phosphatase Isabelle Gerin , Gaëtane Noël and Emile Van Schaftingen Laboratory of…”
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