Antiplasmodial Effect of Commelina benghalensis/Steganotaenia araliacea Plants Extract on the Human Population in Ngaoundere (Cameroon)
The study was conducted in the laboratories of the Provincial hospital and the University of Ngaoundere. The study was to assess the frequencies and the parasites densities of Plasmodium spp. and the effects of leaves and bark extract of Commelina benghalensis/Steganotaenia araliacea on the malaria...
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| Published in: | Journal of medical sciences (Faisalābād, Pakistan) Vol. 14; no. 2; pp. 68 - 74 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
2014
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| Subjects: | |
| Online Access: | Get full text |
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| Summary: | The study was conducted in the laboratories of the Provincial hospital and the University of Ngaoundere. The study was to assess the frequencies and the parasites densities of Plasmodium spp. and the effects of leaves and bark extract of Commelina benghalensis/Steganotaenia araliacea on the malaria parasite. Blood was sampled from patients coming to the hospital for examination. They were submitted for treatment with the plants extract for ten days and with amodiaquine for three days. Sampling on 109 patients revealed that the infestation due to Plasmodium falciparum and Plasmodium malariae was 73.4%. The results indicated that malaria is endemic in Ngaoundere where the average infestation is 74.3% and where Plasmodium falciparum is the main causative agent. The infestation varied from one quarter to another with elevated values in Haoussa quarter. The parasite density had the same tendency as that of the infestation. Treatment of patients with a mixture of Commelina benghalensis/Steganotaenia araliacea extract revealed a progressive reduction of infestation up to a total dispiriting of the parasites after 10 days. Five days after the beginning of treatment of patients with plants extract, the average parasite density was significantly reduced (p<0.05), whatever were the resident quarter, the sex and age of patient. When patients were treated with amodiaquine, all the parasites were eliminated 3 days after the beginning of treatment. |
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| Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 1682-4474 1812-5727 |
| DOI: | 10.3923/jms.2014.68.74 |