Search Results - "Nliwasa, Marriott"
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Spatial distribution and characteristics of women reporting cervical cancer screening in Malawi: An analysis of the 2020 to 2021 Malawi Population-based HIV Impact Assessment survey data
Published in PloS one (10-10-2024)“…Malawi has one of the highest incidence and mortality rates of cervical cancer in the world. Despite a national strategic plan and the roll-out of VIA and…”
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Specific human gene expression in response to infection is an effective marker for diagnosis of latent and active tuberculosis
Published in Scientific reports (06-11-2024)“…RNA sequencing and microarray analysis revealed transcriptional markers expressed in whole blood can differentiate active pulmonary TB (ATB) from other…”
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Effects of Coronavirus Disease Pandemic on Tuberculosis Notifications, Malawi
Published in Emerging infectious diseases (01-07-2021)“…The coronavirus disease (COVID-19) pandemic might affect tuberculosis (TB) diagnosis and patient care. We analyzed a citywide electronic TB register in…”
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Tuberculosis case notifications in Malawi have strong seasonal and weather-related trends
Published in Scientific reports (25-02-2021)“…Seasonal trends in tuberculosis (TB) notifications have been observed in several countries but are poorly understood. Explanatory factors may include weather,…”
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Effect of patient-delivered household contact tracing and prevention for tuberculosis: A household cluster-randomised trial in Malawi
Published in PloS one (08-09-2022)“…Household contact tracing provides TB screening and TB preventive therapy (TPT) to contacts at high risk of TB disease. However, it is resource intensive,…”
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Utility of broad-spectrum antibiotics for diagnosing pulmonary tuberculosis in adults: a systematic review and meta-analysis
Published in The Lancet infectious diseases (01-09-2020)“…Suboptimal diagnostics for pulmonary tuberculosis drive the use of the so-called trial of antibiotics, a course of broad-spectrum antibiotics without activity…”
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The Effect of Real-Time Medication Monitoring-Based Digital Adherence Tools on Adherence to Antiretroviral Therapy and Viral Suppression in People Living With HIV: A Systematic Literature Review and Meta-Analysis
Published in Journal of acquired immune deficiency syndromes (1999) (15-08-2024)“…Universal antiretroviral therapy (ART) has led to improved treatment outcomes in persons living with HIV. Adherence to ART is required to achieve viral…”
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Suppression of host gene expression is associated with latent TB infection: a possible diagnostic biomarker
Published in Scientific reports (07-07-2024)“…The World Health Organization End TB strategy aims for a 90% reduction of tuberculosis (TB) incidence by 2035. Systematic testing and treatment of latent TB…”
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Community-based active case-finding interventions for tuberculosis: a systematic review
Published in The Lancet. Public health (01-05-2021)“…Community-based active case-finding interventions might identify and treat more people with tuberculosis disease than standard case detection. We aimed to…”
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Diagnostic accuracy of a three-gene Mycobacterium tuberculosis host response cartridge using fingerstick blood for childhood tuberculosis: a multicentre prospective study in low-income and middle-income countries
Published in The Lancet infectious diseases (01-02-2024)“…Childhood tuberculosis remains a major cause of morbidity and mortality in part due to missed diagnosis. Diagnostic methods with enhanced sensitivity using…”
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Pattern of abnormalities amongst chest X‐rays of adults undergoing computer‐assisted digital chest X‐ray screening for tuberculosis in Peri‐Urban Blantyre, Malawi: A cross‐sectional study
Published in Tropical medicine & international health (01-11-2021)“…Background The prevalence of diseases other than tuberculosis (TB) detected during chest X‐ray screening is poorly described in sub‐Saharan Africa…”
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Computer-aided X-ray screening for tuberculosis and HIV testing among adults with cough in Malawi (the PROSPECT study): A randomised trial and cost-effectiveness analysis
Published in PLoS medicine (01-09-2021)“…Suboptimal tuberculosis (TB) diagnostics and HIV contribute to the high global burden of TB. We investigated costs and yield from systematic HIV-TB screening,…”
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Durations of asymptomatic, symptomatic, and care-seeking phases of tuberculosis disease with a Bayesian analysis of prevalence survey and notification data
Published in BMC medicine (10-11-2021)“…Ratios of bacteriologically positive tuberculosis (TB) prevalence to notification rates are used to characterise typical durations of TB disease. However, this…”
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Effectiveness of spatially targeted interventions for control of HIV, tuberculosis, leprosy and malaria: a systematic review
Published in BMJ open (13-07-2021)“…BackgroundAs infectious diseases approach global elimination targets, spatial targeting is increasingly important to identify community hotspots of…”
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Clinical, health systems and neighbourhood determinants of tuberculosis case fatality in urban Blantyre, Malawi: a multilevel epidemiological analysis of enhanced surveillance data
Published in Epidemiology and infection (02-09-2021)“…Abstract We investigated whether household to clinic distance was a risk factor for death on tuberculosis (TB) treatment in Malawi. Using enhanced TB…”
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Disparities in access to diagnosis and care in Blantyre, Malawi, identified through enhanced tuberculosis surveillance and spatial analysis
Published in BMC medicine (29-01-2019)“…A sizeable fraction of tuberculosis (TB) cases go undiagnosed. By analysing data from enhanced demographic, microbiological and geospatial surveillance of TB…”
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Neighbourhood prevalence-to-notification ratios for adult bacteriologically-confirmed tuberculosis reveals hotspots of underdiagnosis in Blantyre, Malawi
Published in PloS one (23-05-2022)“…Local information is needed to guide targeted interventions for respiratory infections such as tuberculosis (TB). Case notification rates (CNRs) are readily…”
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The Sensitivity and Specificity of Loop-Mediated Isothermal Amplification (LAMP) Assay for Tuberculosis Diagnosis in Adults with Chronic Cough in Malawi
Published in PloS one (12-05-2016)“…Current tuberculosis diagnostics lack sensitivity, and are expensive. Highly accurate, rapid and cheaper diagnostic tests are required for point of care use in…”
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Tuberculosis Immunoreactivity Surveillance in Malawi (Timasamala)-A protocol for a cross-sectional Mycobacterium tuberculosis immunoreactivity survey in Blantyre, Malawi
Published in PloS one (24-05-2024)“…Tuberculosis (TB) transmission and prevalence are dynamic over time, and heterogeneous within populations. Public health programmes therefore require…”
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Design and protocol for a cluster randomised trial of enhanced diagnostics for tuberculosis screening among people living with HIV in hospital in Malawi (CASTLE study)
Published in PloS one (10-01-2022)“…People living with HIV (PLHIV) have a high risk of death if hospitalised in low-income countries. Tuberculosis has long been the leading cause of admission and…”
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