Search Results - "Njume, Ferdinand Ngale"
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The Functional Parasitic Worm Secretome: Mapping the Place of Onchocerca volvulus Excretory Secretory Products
Published in Pathogens (Basel) (23-11-2020)“…Nematodes constitute a very successful phylum, especially in terms of parasitism. Inside their mammalian hosts, parasitic nematodes mainly dwell in the…”
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The GPI sidechain of Toxoplasma gondii inhibits parasite pathogenesis
Published in mBio (20-09-2024)“…Glycosylphosphatidylinositols (GPIs) are highly conserved anchors for eukaryotic cell surface proteins. The apicomplexan parasite, , is a widespread…”
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Prediction and validation of the structural features of Ov58GPCR, an immunogenic determinant of Onchocerca volvulus
Published in PloS one (26-09-2018)“…Onchocerciasis is a severely debilitating yet neglected tropical disease (NTD) that creates social stigma, generates and perpetuates poverty, and leads…”
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Identification and characterization of the Onchocerca volvulus Excretory Secretory Product Ov28CRP, a putative GM2 activator protein
Published in PLoS neglected tropical diseases (01-07-2019)“…Onchocerca volvulus is the nematode pathogen responsible for human onchocerciasis also known as "River blindness", a neglected tropical disease that affects up…”
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A lipid transfer protein ensures nematode cuticular impermeability
Published in iScience (18-11-2022)“…The cuticle of C. elegans is impermeable to chemicals, toxins, and pathogens. However, increased permeability is a desirable phenotype because it facilitates…”
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Computational Design and Preliminary Serological Analysis of a Novel Multi-Epitope Vaccine Candidate against Onchocerciasis and Related Filarial Diseases
Published in Pathogens (Basel) (21-01-2021)“…Onchocerciasis is a skin and eye disease that exerts a heavy socio-economic burden, particularly in sub-Saharan Africa, a region which harbours greater than…”
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In-silico design of a multi-epitope vaccine candidate against onchocerciasis and related filarial diseases
Published in Scientific reports (13-03-2019)“…Onchocerciasis is a parasitic disease with high socio-economic burden particularly in sub-Saharan Africa. The elimination plan for this disease has faced…”
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A lipid transfer protein ensures nematode cuticular impermeability
Published in iScience (01-10-2022)“…The cuticle of C. elegans is impermeable to chemicals, toxins, and pathogens. However, increased permeability is a desirable phenotype because it facilitates…”
Get full text
Journal Article