Search Results - "Nji, Akindeh"

Parasite clearance and protection from Plasmodium falciparum infection (PCPI): a three-arm, parallel, double-blinded, placebo-controlled, randomised trial of presumptive sulfadoxine-pyrimethamine versus sulfadoxine-pyrimethamine plus amodiaquine versus artesunate monotherapy among asymptomatic children 3-5 years of age in Cameroon by Martinez-Vega, Rosario, Mbacham, Wilfred Fon, Ali, Innocent, Nji, Akindeh, Mousa, Andria, Beshir, Khalid B, Chopo-Pizarro, Ana, Kaur, Harparkash, Okell, Lucy, Hansson, Helle, Hocke, Emma Filtenborg, Alifrangis, Michael, Gosling, Roland, Roper, Cally, Sutherland, Colin, Chico, R Matthew

“…The World Health Organization 2022 malaria chemoprevention guidelines recommend providing a full course of antimalarial treatment at pre-defined intervals,…”
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Effectiveness of malaria chemoprevention in the first two years of life in Cameroon and Côte d'Ivoire compared to standard of care: study protocol for a population-based prospective cohort impact evaluation study by Stresman, Gillian, Lal, Sham, Bruce, Jane, Nji, Akindeh, Serge-Brice, Assi, Mosoff, Jonna, McGirr, Alba, Gore-Langton, Georgia, McGuire, Michaela, Sinsai, James, Lele, Albertine, Tah-Monunde, Mercy, Kouadio, Zah-Bi, Anatole, Mian, Konate-Toure, Abibatou, Clarke, Sian Elisabeth, Gosling, Roland, Mbacham, Wilfred Fon, Yavo, William, Chico, R Matthew

“…Perennial malaria chemoprevention (PMC) is a chemoprevention strategy endorsed by the World Health Organization (WHO) and is increasingly being adopted by…”
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Drug resistance markers within an evolving efficacy of anti-malarial drugs in Cameroon: a systematic review and meta-analysis (1998-2020) by Niba, Peter Thelma Ngwa, Nji, Akindeh M, Evehe, Marie-Solange, Ali, Innocent M, Netongo, Palmer Masumbe, Ngwafor, Randolph, Moyeh, Marcel N, Ngum, Lesley Ngum, Ndum, Oliva Ebie, Acho, Fon Abongwa, Mbu'u, Cyrille Mbanwi, Fosah, Dorothy A, Atogho-Tiedeu, Barbara, Achonduh-Atijegbe, Olivia, Djokam-Dadjeu, Rosine, Chedjou, Jean Paul Kengne, Bigoga, Jude D, Moukoko, Carole Else Eboumbou, Ajua, Anthony, Achidi, Eric, Tallah, Esther, Leke, Rose G F, Tourgordi, Alexis, Ringwald, Pascal, Alifrangis, Michael, Mbacham, Wilfred F

“…Malaria remains highly endemic in Cameroon. The rapid emergence and spread of drug resistance was responsible for the change from monotherapies to…”
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Basic or enhanced clinician training to improve adherence to malaria treatment guidelines: a cluster-randomised trial in two areas of Cameroon by Mbacham, Wilfred F, ScD, Mangham-Jefferies, Lindsay, MBA, Cundill, Bonnie, MSc, Achonduh, Olivia A, MPhil, Chandler, Clare I R, PhD, Ambebila, Joel N, MPH, Nkwescheu, Armand, MPH, Forsah-Achu, Dorothy, MD, Ndiforchu, Victor, MPH, Tchekountouo, Odile, MD, Akindeh-Nji, Mbuh, MSc, Ongolo-Zogo, Pierre, MPH, Wiseman, Virginia, Dr

“…Summary Background The scale-up of malaria rapid diagnostic tests (RDTs) is intended to improve case management of fever and targeting of artemisinin-based…”
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Discrete Survival Model Analysis of Plasmodium falciparum Response to Artemisinin-Based Combination Therapies among Children in Regions of Varying Malaria Transmission in Cameroon by Nji, Akindeh M., Ali, Innocent M., Niba, Peter Thelma Ngwa, Marie-Solange, Evehe, Heumann, Christian, Froeschl, Guenter, Mbacham, Wilfred F.

“…The need to monitor changes in parasite clearance following treatment with artemisinin-based combination therapies (ACTs) is important in the containment of…”
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Randomized non-inferiority and safety trial of dihydroartemisin-piperaquine and artesunate-amodiaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Cameroonian children by Nji, Akindeh M, Ali, Innocent M, Moyeh, Marcel N, Ngongang, Eric-Oliver, Ekollo, Aristide M, Chedjou, Jean-Paul, Ndikum, Valentine N, Evehe, Marie S, Froeschl, Guenter, Heumann, Christian, Mansmann, Ulrich, Ogundahunsi, Olumide, Mbacham, Wilfred F

“…Artemether-lumefantrine and artesunate-amodiaquine are first-line treatment for uncomplicated malaria in Cameroon. No study has yet compared the efficacy of…”
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Comparison of the Accuracy of Four Malaria Diagnostic Methods in a High Transmission Setting in Coastal Cameroon by Mbacham, Wilfred F., Ghogomu, Stephen M., Evehe, Marie S., Netongo, Palmer M., Nji, Akindeh M., Njimoh, Dieudonné Lemuh, Ali, Innocent M., Moyeh, Marcel N., Atogho-Tiedeu, Barbara

“…Background. Despite recommendation from the World Health Organization that all malaria suspected patients undergo a parasitological confirmation using rapid…”
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Depression management and antiretroviral treatment outcome among people living with HIV in Northwest and East regions of Cameroon by Ndenkeh, Jackson Jr Nforbewing, Nji, Akindeh Mbuh, Yumo, Habakkuk Azinyui, Rothe, Camilla, Kroidl, Arne

“…Abstract Background Several interventions have shown benefits in improving mental health problems such as depression which is common in people living with HIV…”
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Malaria prevalence and treatment of febrile patients at health facilities and medicine retailers in Cameroon by Mangham, Lindsay J., Cundill, Bonnie, Achonduh, Olivia A., Ambebila, Joel N., Lele, Albertine K., Metoh, Theresia N., Ndive, Sarah N., Ndong, Ignatius C., Nguela, Rachel L., Nji, Akindeh M., Orang‐Ojong, Barnabas, Wiseman, Virginia, Pamen‐Ngako, Joelle, Mbacham, Wilfred F.

“…Objective  To investigate the quality of malaria case management in Cameroon 5 years after the adoption of artemisinin‐based combination therapy (ACT)…”
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Efficacy of amodiaquine, sulphadoxine-pyrimethamine and their combination for the treatment of uncomplicated Plasmodium falciparum malaria in children in Cameroon at the time of policy change to artemisinin-based combination therapy by Mbacham, Wilfred F, Evehe, Marie-Solange B, Netongo, Palmer M, Ateh, Isabel A, Mimche, Patrice N, Ajua, Anthony, Nji, Akindeh M, Irenee, Domkam, Echouffo-Tcheugui, Justin B, Tawe, Bantar, Hallett, Rachel, Roper, Cally, Targett, Geoffrey, Greenwood, Brian

“…The efficacy of amodiaquine (AQ), sulphadoxine-pyrimethamine (SP) and the combination of SP+AQ in the treatment of Cameroonian children with clinical malaria…”
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A cost-effectiveness analysis of provider interventions to improve health worker practice in providing treatment for uncomplicated malaria in Cameroon: a study protocol for a randomized controlled trial by Wiseman, Virginia, Mangham, Lindsay J, Cundill, Bonnie, Achonduh, Olivia A, Nji, Akindeh Mbuh, Njei, Abanda Ngu, Chandler, Clare, Mbacham, Wilfred F

“…Governments and donors all over Africa are searching for sustainable, affordable and cost-effective ways to improve the quality of malaria case management…”
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Evolution of Plasmodium falciparum antimalarial drug resistance markers post-adoption of artemisinin-based combination therapies in Yaounde, Cameroon by Niba, Peter Thelma Ngwa, Nji, Akindeh Mbuh, Chedjou, Jean Paul Kengne, Hansson, Helle, Hocke, Emma Filtenborg, Ali, Innocent Mbulli, Achonduh-Atijegbe, Olivia, Evehe, Marie-Solange B., Jørgensen, Marie Helene Munck, Fomboh, Calvino Tah, Cui, Liwang, Stresman, Gillian, Bigoga, Jude D., Alifrangis, Michael, Mbacham, Wilfred F.

“…•Drug resistance markers data were compared before and after the adaption of artemisinin-based combination therapies.•The Pfcrt K76T and Pfmdr1 N86Y mutations…”
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Effects of Drug Policy Changes on Evolution of Molecular Markers of Plasmodium falciparum Resistance to Chloroquine, Amodiaquine, and Sulphadoxine-Pyrimethamine in the South West Region of Cameroon by Moyeh, Marcel N., Njimoh, Dieudonne L., Evehe, Marie Solange, Ali, Innocent M., Nji, Akindeh M., Nkafu, Dominique N., Masumbe, Palmer N., Barbara, Atogho-Tiedeu, Ndikum, Valentine N., Mbacham, Wilfred F.

“…Background. As a result of the spread of parasites resistant to antimalarial drugs, Malaria treatment guidelines in Cameroon evolved from nonartemisinin…”
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Active case finding: comparison of the acceptability, feasibility and effectiveness of targeted versus blanket provider-initiated-testing and counseling of HIV among children and adolescents in Cameroon by Yumo, Habakkuk Azinyui, Kuaban, Christopher, Ajeh, Rogers Awoh, Nji, Akindeh Mbuh, Nash, Denis, Kathryn, Anastos, Beissner, Marcus, Loescher, Thomas

“…Children and adolescents still lag behind adults in accessing antiretroviral therapy (ART), which is largely due to their limited access to HIV testing…”
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Adverse Drug Reactions Associated with CYP 2B6 Polymorphisms in HIV/AIDS-Treated Patients in Yaoundé, Cameroon by Nguefeu Nkenfou, Carine, Atogho Tiedeu, Barbara, Nguefeu Nkenfou, Celine, Nji, Akindeh M, Chedjou, Jean Paul, Tah Fomboh, Calvino, Kouanfack, Charles, Mbacham, Wilfred F

“…The metabolism of antiretroviral drugs is subject to individual variations of the CYP 2B6 gene. The objective of this study was to evaluate the prevalence of…”
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Effectiveness and safety of artesunate-amodiaquine versus artemether-lumefantrine for home-based treatment of uncomplicated Plasmodium falciparum malaria among children 6-120 months in Yaoundé, Cameroon: a randomized trial by Niba, Peter Thelma Ngwa, Nji, Akindeh Mbuh, Ali, Innocent Mbulli, Akam, Lawrence Fonyonga, Dongmo, Cedric Hermann, Chedjou, Jean Paul Kengne, Fomboh, Calvino Tah, Nana, William Dorian, Oben, Ornella Laetitia Ayem, Selly-Ngaloumo, Abdel Aziz, Moyeh, Marcel N, Ngu, Jude Achidi, Ludovic, Ambassa Jean, Aboh, Pierre Martiniel, Ambani, Marie Carine Enyegue, Omgba, Pierrette Albertine Mbarga, Kotcholi, Grâce Bissohong, Adzemye, Linus Moye, Nna, Danielle Regine Abenkou, Douanla, Adèle, Ango, Ze, Ewane, Marie Sophie, Ticha, Joel Tewara, Tatah, Fritz Mbuh, Dinza, Golwa, Ndikum, Valentine Nchafor, Fosah, Dorothy A, Bigoga, Jude D, Alifrangis, Michael, Mbacham, Wilfred F

“…Many studies have reported high efficacy and safety of artesunate-amodiaquine (AS-AQ) and artemether-lumefantrine (AL) when administered under direct…”
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Assessing Asymptomatic Malaria Carriage of Plasmodium falciparum and Non-falciparum Species in Children Resident in Nkolbisson, Yaoundé, Cameroon by Akindeh, Nji Mbuh, Ngum, Lesley Ngum, Niba, Peter Thelma Ngwa, Ali, Innocent Mbulli, Ayem, Ornella Laetitia Oben, Chedjou, Jean Paul Kengne, Fomboh, Calvino Tah, Ekollo, Aristid Herve Mbange, Mbu’u, Cyrille Mbanwi, Mbacham, Wilfred Fon

“…Malaria is still a threat to public health as it remains the first endemic disease in the world. It is a pervasive parasitic disease in tropical and…”
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Allelic frequencies of mutants of the Plasmodium falciparum, quinoline and folate metabolizing genes in the west region of Cameroon by Ali, Innocent Mbulli, Tchuenkam, Valery Pacome Kom, Tagomo, Sandra Sob, Mawamba, Hornela, Moyeh, Marcel Nyuylam, Nfor, Emmanuel Nfor, Nji, Akindeh Mbuh, Fomboh, Calvino Tah, Nana, William Dorian, Kengne, Jean-Paul Chedjou, Niba, Peter Thelma Ngwa, Ekoyol, Germaine Ekobo, Achu, Dorothy Fosah, Bigoga, Jude Daiga, Mbacham, Wilfred Fon

“…The emergence and spread of Plasmodium falciparum (P.f) drug resistance is still a major concern in Sub-Saharan Africa and warrants that its evolution be…”
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Diagnostic Accuracy of CareStart™ Malaria HRP2 and SD Bioline Pf/PAN for Malaria in Febrile Outpatients in Varying Malaria Transmission Settings in Cameroon by Ali, Innocent Mbulli, Nji, Akindeh Mbuh, Bonkum, Jacob Chefor, Moyeh, Marcel Nyuylam, Carole, Guenang Kenfack, Efon, Agni, Dabou, Solange, Tchuenkam, Valery Pacome Kom, Tah, Calvino, Kengne, Jean-Paul Chedjou, Achu, Dorothy Fosah, Bigoga, Jude Daiga, Mbacham, Wilfred Fon

“…Background: There was an increase in the number of malaria cases in Cameroon in 2018 that could reflect changes in provider practice, despite effective…”
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Predominance of N-acetyl transferase 2 slow acetylator alleles in children less than ten years experiencing adverse treatment events following artemisinin-based combination therapy in North and South West Regions of Cameroon by Jean, P C Kengne, Akindeh, M Nji, Innocent, M Ali, Olivia, Ekollo, M Aristid, Wilfred, F Mbacham

“…The human N-acetyltransferase II (NAT2) gene may vary between individuals resulting in variability in the incidence of adverse drug reactions. We set out in…”
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