Search Results - "Njayou, Nico Frederic"
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Inhibitory activity of limonoids from Khaya grandifoliola C.DC (Meliaceae) against hepatitis C virus infection in vitro
Published in Avicenna journal of phytomedicine (01-07-2021)“…OBJECTIVEA fraction from Khaya grandifoliola has recently been shown to inhibit hepatitis C virus (HCV) infection and three limonoids…”
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Inhibition of CYP2E1 and activation of Nrf2 signaling pathways by a fraction from Entada africana alleviate carbon tetrachloride-induced hepatotoxicity
Published in Heliyon (01-08-2020)“…Entada africana is used in non-conventional medicine for the management of liver ailments. A fraction, designated EaF10 (methylene chloride/methanol 90:10,…”
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Liver injury in malaria infected patients in Douala-Cameroon and its association with poor medical practice
Published in Egyptian Liver Journal (22-11-2023)“…BackgroundMalaria is an endemic mosquito-borne disease in sub-Saharan regions, including Cameroon. Due to the obligatory hepatic stage of its pathogenic…”
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Hydro-ethanolic extract of Khaya grandifoliola attenuates heavy metals-induced hepato-renal injury in rats by reducing oxidative stress and metals-bioaccumulation
Published in Heliyon (01-11-2022)“…People living in developing countries are exposed to hepato-renal injuries induced by heavy metals like lead (Pb), cadmium (Cd), and mercury (Hg) since…”
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Rubescins A, B and C: New Havanensin Type Limonoids from Root Bark of Trichilia rubescens (Meliaceae)
Published in Chemical & pharmaceutical bulletin (2013)“…Three new limonoids, rubescins A–C (1–3), and three known compounds including, havanensin type limonoid TS3 (4), β-sitosterol, and stigmasterol were isolated…”
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Antioxidant fractions of Khaya grandifoliola C.DC. and Entada africana Guill. et Perr. induce nuclear translocation of Nrf2 in HC-04 cells
Published in Cell stress & chaperones (01-11-2015)“…The in vitro antioxidant properties, cytoprotective activity, and ability to induce nuclear translocation of nuclear factor E2-related factor-2 (Nrf-2) of five…”
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Khaya grandifoliola C.DC: a potential source of active ingredients against hepatitis C virus in vitro
Published in Archives of virology (01-05-2016)“…In this study, we examined the antiviral properties of Khaya grandifoliola C.DC (Meliaceae) on the hepatitis C virus (HCV) life cycle in vitro and identified…”
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Active chemical fractions of stem bark extract of Khaya grandifoliola C.DC and Entada africana Guill. et Perr. synergistically protect primary rat hepatocytes against paracetamol-induced damage
Published in BMC complementary and alternative medicine (07-07-2016)“…Khaya grandifoliola (Meliaceae) and Entada africana (Fabaceae) are traditionally used in Bamun (a western tribe of Cameroon) traditional medicine for the…”
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Antidiarrheal Activity of Dissotis multiflora (Sm) Triana (Melastomataceae) Leaf Extract in Wistar Rats and Subacute Toxicity Evaluation
Published in Evidence-based complementary and alternative medicine (01-01-2017)“…The present work was undertaken to evaluate antidiarrheal activity of ethanolic leaf extract of Dissotis multiflora (Sm) Triana (D. multiflora) on Shigella…”
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New Insights into Bioactive Compounds from the Medicinal Plant Spathodea campanulata P. Beauv. and Their Activity against Helicobacter pylori
Published in Antibiotics (Basel) (15-05-2020)“…The medicinal plant P. Beauv. (Bignoniaceae) has been traditionally applied for the prevention and treatment of diseases of the kidney and urinary system, the…”
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Ochratoxin A in black pepper, white pepper and clove sold in Yaoundé (Cameroon) markets: contamination levels and consumers’ practices increasing health risk
Published in International journal of food contamination (2018)“…Background Spices are widely consumed in Cameroon, but there is no data available concerning their mycotoxin contamination. A cross-sectional study was…”
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Plants extracts from Cameroon pharmacopeia strongly inhibit the Chikungunya virus infection by targeting entry and replication steps
Published in Journal of ethnopharmacology (05-10-2022)“…Cameroon is one of the sub-Saharan African countries affected by Chikungunya virus (CHIKV). With the absence of approved treatment, this disease represents…”
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A fraction of stem bark extract of Entada africana suppresses lipopolysaccharide-induced inflammation in RAW 264.7 cells
Published in Journal of ethnopharmacology (26-08-2013)“…Entada africana is a plant used in African traditional medicine for the treatment of stomachache, fever, liver related diseases, wound healing, cataract and…”
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Inhibitory effect of medicinal plants from Cameroon on the growth and adhesion of Helicobacter pylori
Published in European journal of integrative medicine (01-09-2019)“…Plants in the Cameroon Pharmacopoeia are used by the population as decoctions, infusions and are macerated to relieve digestive and gastric disorders. The aim…”
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Anti-hepatitis C virus activity of crude extract and fractions of Entada africana in genotype 1b replicon systems
Published in The American journal of Chinese medicine (1979) (2014)“…Entada africana (Ea) is a medicinal plant from the family of Fabaceae, used in Western and Central Africa regions to treat liver diseases. Antiviral properties…”
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Antidiarrheal Activity of Dissotis multiflora Leaf Extract in Wistar Rats and Subacute Toxicity Evaluation
Published in Evidence-based complementary and alternative medicine (01-01-2017)Get full text
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Delayed treatment with hydro-ethanolic extract of Khaya grandifoliola protects mice from acetaminophen-hepatotoxicity through inhibition of c-Jun N-terminal kinase phosphorylation and mitochondrial dysfunction
Published in Pharmaceutical Science Advances (01-12-2024)“…The use of N-acetylcysteine against acetaminophen(APAP)-induced hepatotoxicity, a leading cause of liver injury, has several drawbacks, including short…”
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Entada africana fraction CH₂Cl₂/MEOH 5% inhibits inducible nitric oxide synthase and pro-inflammatory cytokines gene expression induced by lipopolysaccharide in microglia
Published in BMC complementary and alternative medicine (03-10-2013)“…Inflammatory response in the CNS mediated by microglia cells play an important role in host defense and is implicated in the pathology of neurodegenerative…”
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Entada africana fraction CH sub(2)Cl sub(2)/MEOH 5% inhibits inducible nitric oxide synthase and pro-inflammatory cytokines gene expression induced by lipopolysaccharide in microglia
Published in BMC complementary and alternative medicine (01-01-2013)“…Background: Inflammatory response in the CNS mediated by microglia cells play an important role in host defense and is implicated in the pathology of…”
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