Search Results - "Njavro, Jasenka"

Click Chemistry-mediated Biotinylation Reveals a Function for the Protease BACE1 in Modulating the Neuronal Surface Glycoproteome by Herber, Julia, Njavro, Jasenka, Feederle, Regina, Schepers, Ute, Müller, Ulrike C., Bräse, Stefan, Müller, Stephan A., Lichtenthaler, Stefan F.

“…The cell surface proteome is dynamic and has fundamental roles in cell signaling. Many surface membrane proteins are proteolytically released into a cell's…”
Get full text

The β-Secretase Substrate Seizure 6–Like Protein (SEZ6L) Controls Motor Functions in Mice by Ong-Pålsson, Emma, Njavro, Jasenka Rudan, Wilson, Yvette, Pigoni, Martina, Schmidt, Andree, Müller, Stephan A., Meyer, Michael, Hartmann, Jana, Busche, Marc Aurel, Gunnersen, Jenny M., Munro, Kathryn M., Lichtenthaler, Stefan F.

“…The membrane protein seizure 6–like (SEZ6L) is a neuronal substrate of the Alzheimer’s disease protease BACE1, and little is known about its physiological…”
Get full text

Beneficial Effect of ACI-24 Vaccination on Aβ Plaque Pathology and Microglial Phenotypes in an Amyloidosis Mouse Model by Rudan Njavro, Jasenka, Vukicevic, Marija, Fiorini, Emma, Dinkel, Lina, Müller, Stephan A, Berghofer, Anna, Bordier, Chiara, Kozlov, Stanislav, Halle, Annett, Buschmann, Katrin, Capell, Anja, Giudici, Camilla, Willem, Michael, Feederle, Regina, Lichtenthaler, Stefan F, Babolin, Chiara, Montanari, Paolo, Pfeifer, Andrea, Kosco-Vilbois, Marie, Tahirovic, Sabina

“…Amyloid-β (Aβ) deposition is an initiating factor in Alzheimer's disease (AD). Microglia are the brain immune cells that surround and phagocytose Aβ plaques,…”
Get full text

Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3 by Pigoni, Martina, Hsia, Hung‐En, Hartmann, Jana, Rudan Njavro, Jasenka, Shmueli, Merav D, Müller, Stephan A, Güner, Gökhan, Tüshaus, Johanna, Kuhn, Peer‐Hendrik, Kumar, Rohit, Gao, Pan, Tran, Mai Ly, Ramazanov, Bulat, Blank, Birgit, Hipgrave Ederveen, Agnes L, Von Blume, Julia, Mulle, Christophe, Gunnersen, Jenny M, Wuhrer, Manfred, Rammes, Gerhard, Busche, Marc Aurel, Koeglsperger, Thomas, Lichtenthaler, Stefan F

“…Seizure protein 6 (SEZ6) is required for the development and maintenance of the nervous system, is a major substrate of the protease BACE1 and is linked to…”
Get full text

Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1 by Rudan Njavro, Jasenka, Klotz, Jakob, Dislich, Bastian, Wanngren, Johanna, Shmueli, Merav D., Herber, Julia, Kuhn, Peer‐Hendrik, Kumar, Rohit, Koeglsperger, Thomas, Conrad, Marcus, Wurst, Wolfgang, Feederle, Regina, Vlachos, Andreas, Michalakis, Stylianos, Jedlicka, Peter, Müller, Stephan A., Lichtenthaler, Stefan F.

“…The protease beta‐site APP cleaving enzyme 1 (BACE1) has fundamental functions in the nervous system. Its inhibition is a major therapeutic approach in…”
Get full text

Cholesterol-depletion corrects APP and BACE1 misstrafficking in NPC1-deficient cells by Malnar, Martina, Kosicek, Marko, Lisica, Ana, Posavec, Melanija, Krolo, Ana, Njavro, Jasenka, Omerbasic, Damir, Tahirovic, Sabina, Hecimovic, Silva

“…Cholesterol accumulation in Niemann–Pick type C disease (NPC) causes increased levels of the amyloid-precursor-protein C-terminal fragments (APP-CTFs) and…”
Get full text