Search Results - "Njau, Florence"

Calcium Dobesilate Modulates PKCδ-NADPH Oxidase- MAPK-NF-κB Signaling Pathway to Reduce CD14, TLR4, and MMP9 Expression during Monocyte-to-Macrophage Differentiation: Potential Therapeutic Implications for Atherosclerosis by Njau, Florence, Haller, Hermann

“…Monocyte-to-macrophage differentiation results in the secretion of various inflammatory mediators and oxidative stress molecules necessary for atherosclerosis…”
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Calcium dobesilate reduces VEGF signaling by interfering with heparan sulfate binding site and protects from vascular complications in diabetic mice by Njau, Florence, Shushakova, Nelli, Schenk, Heiko, Wulfmeyer, Vera Christine, Bollin, Robin, Menne, Jan, Haller, Hermann

“…Inhibiting vascular endothelial growth factor (VEGF) is a therapeutic option in diabetic microangiopathy. However, VEGF is needed at physiological…”
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Correction: Calcium dobesilate reduces VEGF signaling by interfering with heparan sulfate binding site and protects from vascular complications in diabetic mice by Njau, Florence, Shushakova, Nelli, Schenk, Heiko, Wulfmeyer, Vera Christine, Bollin, Robin, Menne, Jan, Haller, Hermann

“…[This corrects the article DOI: 10.1371/journal.pone.0218494.]…”
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DataLawCompanion: Enhancing Data Protection Law Compliance in the Digital Age by Nderu, Lawrence, Oginga, Ruth, Butichi, Bonface, Rono, John, Njau, Florence, Mogire, Felista, Matindo, Derrick, Muiruri, Daniel, Kiragga, Agnes

“…The rapid expansion and use of digital data in the era of generative Artificial Intelligence raises significant challenges in legal compliance and ethical data…”
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No Correlation between Giant Cell Arteritis and Chlamydia pneumoniae Infection: Investigation of 189 Patients by Standard and Improved PCR Methods by Njau, Florence, Ness, Thomas, Wittkop, Ulrike, Pancratz, Thorsten, Eickhoff, Meike, Hudson, Alan P, Haller, Hermann, Wagner, Annette D

“…A total of 189 temporal artery biopsy samples from giant cell arteritis (GCA) patients were investigated using sensitive PCR targeting Chlamydia pneumoniae…”
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Differential infection outcome of Chlamydia trachomatis in human blood monocytes and monocyte-derived dendritic cells by Datta, Baishakhi, Njau, Florence, Thalmann, Jessica, Haller, Hermann, Wagner, Annette D

“…Chlamydia trachomatis is an intracellular bacteria which consist of three biovariants; trachoma (serovars A-C), urogenital (serovars D-K) and lymphogranuloma…”
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Restriction of Chlamydia pneumoniae replication in human dendritic cell by activation of indoleamine 2,3-dioxygenase by Njau, Florence, Geffers, Robert, Thalmann, Jessica, Haller, Hermann, Wagner, Annette Doris

“…Infection with Chlamydia pneumoniae, a human respiratory pathogen, has been associated with various chronic diseases such as asthma and atherosclerosis,…”
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Pharmacological Tie2 activation in kidney transplantation by Thamm, Kristina, Njau, Florence, Van Slyke, Paul, Dumont, Daniel J, Park, Joon-Keun, Haller, Hermann, David, Sascha

“…To investigate the therapeutic potential of vasculotide (VT) - a Tie2 activating therapeutic - in kidney transplantation. We performed a murine MHC-mismatched…”
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Identification of high- and low-virulent strains of Chlamydia pneumoniae by their characterization in a mouse pneumonia model by Sommer, Kirsten, Njau, Florence, Wittkop, Ulrike, Thalmann, Jessica, Bartling, Gerda, Wagner, Annette, Klos, Andreas

“…Contradicting reports exist about the pathogenicity of Chlamydia pneumoniae and the severity of the respiratory disease they cause. This study aimed to…”
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In vitro neutralization of tumor necrosis factor-α during Chlamydia pneumoniae infection impairs dendritic cells maturation/function and increases chlamydial progeny by Njau, Florence, Wittkop, Ulrike, Rohde, Manfred, Haller, Hermann, Klos, Andreas, Wagner, Annette Doris

“…Dendritic cells (DCs) produce tumor necrosis factor (TNF)-α upon infection and contribute in various ways to defense against pathogenic agents. Several…”
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Staining of Chlamydia trachomatis elementary bodies: A suitable method for identifying infected human monocytes by flow cytometry by Schnitger, Karen, Njau, Florence, Wittkop, Ulrike, Liese, Andrea, Kuipers, Jens G., Thiel, Andreas, Morgan, Michael A., Zeidler, Henning, Wagner, Annette D.

“…Persistence of Chlamydia trachomatis ( C. trachomatis) in the joint is the most frequent cause of reactive arthritis following urogenital tract infection. The…”
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Transmission of Chlamydophila pneumoniae from dendritic cells to macrophages does not require cell-to-cell contact in vitro by Wittkop, Ulrike, Peppmueller, Matthias, Njau, Florence, Leibold, Wolfgang, Klos, Andreas, Krausse-Opatz, Birgit, Hudson, Alan P., Zeidler, Henning, Haller, Hermann, Wagner, Annette D.

“…Chlamydophila pneumoniae (C. pneumoniae) has been detected in macrophages (Mø) and dendritic cells (DC) in vascular diseases. To understand the importance of…”
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In vitro neutralization of tumor necrosis factor-α during Chlamydia pneumoniae infection impairs dendritic cells maturation/function and increases chlamydial progeny by Njau, Florence, Wittkop, Ulrike, Rohde, Manfred, Haller, Hermann, Klos, Andreas, Wagner, Annette Doris

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In vitro neutralization of tumor necrosis factor-a during Chlamydia pneumoniae infection impairs dendritic cells maturation/function and increases chlamydial progeny by Njau, Florence, Wittkop, Ulrike, Rohde, Manfred, Haller, Hermann, Klos, Andreas, Wagner, Annette Doris

“…AbstractDendritic cells (DCs) produce tumor necrosis factor (TNF)-a upon infection and contribute in various ways to defense against pathogenic agents. Several…”
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In vitro neutralization of tumor necrosis factor-α during Chlamydia pneumoniae infection impairs dendritic cells maturation/function and increases chlamydial progeny: Chlamydia by NJAU, Florence, WITTKOP, Ulrike, ROHDE, Manfred, HALLER, Hermann, KLOS, Andreas, WAGNER, Annette Doris

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Identification of high-and low-virulent strains of Chlamydia pneumoniae by their characterization in a mouse pneumonia model: Chlamydia by SOMMER, Kirsten, NJAU, Florence, WITTKOP, Ulrike, THALMANN, Jessica, BARTLING, Gerda, WAGNER, Annette, KLOS, Andreas

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