Search Results - "Nizou, Angélique"

Amlexanox: Readthrough Induction and Nonsense-Mediated mRNA Decay Inhibition in a Charcot-Marie-Tooth Model of hiPSCs-Derived Neuronal Cells Harboring a Nonsense Mutation in GDAP1 Gene by Benslimane, Nesrine, Miressi, Federica, Loret, Camille, Richard, Laurence, Nizou, Angélique, Pyromali, Ioanna, Faye, Pierre-Antoine, Favreau, Frédéric, Lejeune, Fabrice, Lia, Anne-Sophie

“…Nonsense mutations are involved in multiple peripheral neuropathies. These mutations induce the presence of a premature termination codon (PTC) at the mRNA…”
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Neuroprotective Effect of Polyvalent Immunoglobulins on Mouse Models of Chemotherapy-Induced Peripheral Neuropathy by Mroué, Mohamad, Bessaguet, Flavien, Nizou, Angélique, Richard, Laurence, Sturtz, Franck, Magy, Laurent, Bourthoumieu, Sylvie, Danigo, Aurore, Demiot, Claire

“…The occurrence of neuropathic pain in chemotherapy-induced peripheral neuropathy (CIPN) is a major dose-limiting effect of many commonly-used anticancer…”
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Blockade of Cholecystokinin Type 2 Receptors Prevents the Onset of Vincristine-Induced Neuropathy in Mice by Bernard, Amandine, Danigo, Aurore, Mroué, Mohamad, Rovini, Amandine, Richard, Laurence, Nizou, Angélique, Desmoulière, Alexis, Sturtz, Franck, Demiot, Claire, Bourthoumieu, Sylvie

“…Vincristine (VCR) is responsible for the onset of the VCR-induced peripheral neuropathy (VIPN), associated with neuropathic pain. Several reports have strongly…”
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CRISPR Base Editing to Create Potential Charcot-Marie-Tooth Disease Models with High Editing Efficiency: Human Induced Pluripotent Stem Cell Harboring SH3TC2 Variants by Loret, Camille, Pauset, Amandine, Faye, Pierre-Antoine, Prouzet-Mauleon, Valérie, Pyromali, Ioanna, Nizou, Angélique, Miressi, Federica, Sturtz, Franck, Favreau, Frédéric, Turcq, Béatrice, Lia, Anne-Sophie

“…Human induced pluripotent stem cells (hiPSCs) represent a powerful tool to investigate neuropathological disorders in which the cells of interest are…”
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New structural variations responsible for Charcot-Marie-Tooth disease: The first two large KIF5A deletions detected by CovCopCan software by Pyromali, Ioanna, Perani, Alexandre, Nizou, Angélique, Benslimane, Nesrine, Derouault, Paco, Bourthoumieu, Sylvie, Fradin, Mélanie, Sole, Guilhem, Duval, Fanny, Gomes, Constantin, Favreau, Frédéric, Sturtz, Franck, Magdelaine, Corinne, Lia, Anne-Sophie

“…[Display omitted] Next-generation sequencing (NGS) allows the detection of mutations in inherited genetic diseases, like the Charcot-Marie-Tooth disease (CMT)…”
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In vitro 3D angiogenesis assay in egg white matrix: comparison to Matrigel, compatibility to various species, and suitability for drug testing by Mousseau, Yoanne, Mollard, Séverine, Qiu, Hao, Richard, Laurence, Cazal, Raphael, Nizou, Angélique, Vedrenne, Nicolas, Rémi, Séverine, Baaj, Yasser, Fourcade, Laurent, Funalot, Benoit, Sturtz, Franck G

“…In vitro angiogenesis assays are commonly used to assess pro- or anti-angiogenic drug properties. Extracellular matrix (ECM) substitutes such as Matrigel and…”
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One Multilocus Genomic Variation Is Responsible for a Severe Charcot-Marie-Tooth Axonal Form by Miressi, Federica, Magdelaine, Corinne, Cintas, Pascal, Bourthoumieux, Sylvie, Nizou, Angélique, Derouault, Paco, Favreau, Frédéric, Sturtz, Franck, Faye, Pierre-Antoine, Lia, Anne-Sophie

“…Charcot-Marie-Tooth (CMT) disease is a heterogeneous group of inherited disorders affecting the peripheral nervous system, with a prevalence of 1/2500. So far,…”
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Fingolimod potentiates the effects of sunitinib malate in a rat breast cancer model by Mousseau, Yoanne, Mollard, Séverine, Faucher-Durand, Karine, Richard, Laurence, Nizou, Angélique, Cook-Moreau, Jeanne, Baaj, Yasser, Qiu, Hao, Plainard, Xavier, Fourcade, Laurent, Funalot, Benoit, Sturtz, Franck G.

“…Most of the antiangiogenic strategies used in oncology principally target endothelial cells through the vascular endothelial growth factor (VEGF) pathway…”
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Two novel mutations of the calcium-sensing receptor gene affecting the same amino acid position lead to opposite phenotypes and reveal the importance of p.N802 on receptor activity by Lia-Baldini, Anne-Sophie, Magdelaine, Corinne, Nizou, Angélique, Airault, Coraline, Salles, Jean-Pierre, Moulin, Pierre, Delemer, Brigitte, Aitouares, Mina, Funalot, Benoît, Sturtz, Franck, Lienhardt-Roussie, Anne

“…ObjectiveGain-of-function mutations of the calcium-sensing receptor (CASR) gene have been identified in patients with sporadic or familial autosomal dominant…”
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Fingolimod inhibits PDGF-B-induced migration of vascular smooth muscle cell by down-regulating the S1PR1/S1PR3 pathway by Mousseau, Yoanne, Mollard, Séverine, Richard, Laurence, Nizou, Angélique, Faucher-Durand, Karine, Cook-Moreau, Jeanne, Qiu, Hao, Baaj, Yasser, Funalot, Benoit, Fourcade, Laurent, Sturtz, Franck G.

“…Platelet Derived Growth Factor (PDGF) and sphingosine-1-phosphate (S1P) pathways play a key role in mural cell recruitment during tumor growth and…”
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Characterization of the bovine PRKAG3 gene: structure, polymorphism, and alternative transcripts by Roux, Matthieu, Nizou, Angélique, Forestier, Lionel, Ouali, Ahmed, Levéziel, Hubert, Amarger, Valérie

“…The bovine PRKAG3 gene encodes the AMPK gamma3 subunit, one isoform of the regulatory gamma subunit of the AMP-activated protein kinase (AMPK). The AMPK plays…”
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Amlexanox: Readthrough Induction and Nonsense-Mediated mRNA Decay Inhibition in a Charcot–Marie–Tooth Model of hiPSCs-Derived Neuronal Cells Harboring a Nonsense Mutation in IGDAP1/I Gene by Benslimane, Nesrine, Miressi, Federica, Loret, Camille, Richard, Laurence, Nizou, Angélique, Pyromali, Ioanna, Faye, Pierre-Antoine, Favreau, Frédéric, Lejeune, Fabrice, Lia, Anne-Sophie

“…Nonsense mutations are involved in multiple peripheral neuropathies. These mutations induce the presence of a premature termination codon (PTC) at the mRNA…”
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Fingolimod potentiates the effects of sunitinib malate in a rat breast cancer model by Mousseau, Yoanne, Mollard, Séverine, Faucher-Durand, Karine, Richard, Laurence, Nizou, Angélique, Cook-Moreau, Jeanne, Baaj, Yasser, Qiu, Hao, Plainard, Xavier, Fourcade, Laurent, Funalot, Benoît, Sturtz, Franck

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Characterization of the bovine PRKAG3 gene: structure, polymorphism, and alternative transcripts by Roux, Matthieu, Nizou, Angélique, Forestier, Lionel, Ouali, Ahmed, Levéziel, Hubert H., Amarger, Valérie

“… The bovine PRKAG3 gene encodes the AMPK gamma3 subunit, one isoform of the regulatory gamma subunit of the AMP-activated protein kinase (AMPK). The AMPK plays…”
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One Multilocus Genomic Variation Is Responsible for a Severe Charcot-Marie-Tooth Axonal Form by Miressi, Federica, Magdelaine, Corinne, Cintas, Pascal, Bourthoumieux, Sylvie, Nizou, Angélique, Derouault, Paco, Favreau, Frédéric, Sturtz, Franck, Faye, Pierre-Antoine, Lia, Anne-Sophie

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