Search Results - "Nizhnikov, Michael E"

Restraint stress enhances alcohol intake in adolescent female rats but reduces alcohol intake in adolescent male and adult female rats by Wille-Bille, Aranza, Ferreyra, Ana, Sciangula, Martina, Chiner, Florencia, Nizhnikov, Michael E., Pautassi, Ricardo Marcos

“…•Restraint stress increased alcohol intake in female adolescent Wistar rats.•Restraint stress decreased alcohol intake in male adolescents and female…”
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Prenatal ethanol increases ethanol intake throughout adolescence, alters ethanol-mediated aversive learning, and affects μ but not δ or κ opioid receptor mRNA expression by Fabio, María Carolina, Macchione, Ana Fabiola, Nizhnikov, Michael E., Pautassi, Ricardo Marcos

“…Animal models of prenatal ethanol exposure (PEE) have indicated a facilitatory effect of PEE on adolescent ethanol intake, but few studies have assessed the…”
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Offspring of male rats exposed to binge alcohol exhibit heightened ethanol intake at infancy and alterations in T-maze performance by Hollander, Jessica, McNivens, Megan, Pautassi, Ricardo M., Nizhnikov, Michael E.

“…Alcohol use is associated with a variety of negative consequences, including heightened likelihood of cognitive impairment, proclivity to alcohol use disorders…”
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Transgenerational Transmission of the Effect of Gestational Ethanol Exposure on Ethanol Use-Related Behavior by Nizhnikov, Michael E., Popoola, Daniel O., Cameron, Nicole M.

“…Background Prenatal alcohol exposure (PAE) enhances the risk for alcoholism by increasing the propensity to consume alcohol and altering neurophysiological…”
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Relationship between ethanol-induced activity and anxiolysis in the open field, elevated plus maze, light-dark box, and ethanol intake in adolescent rats by Acevedo, María Belén, Nizhnikov, Michael E., Molina, Juan C., Pautassi, Ricardo Marcos

“…•Ethanol-induced motor activation in the open-field at 1.25, 2.5 and 3.25g/kg dose.•Ethanol-induced anxiolysis in elevated plus maze at 0.5, 1.25 and 2.5g/kg…”
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Restraint stress exacerbates cell degeneration induced by acute binge ethanol in the adolescent, but not in the adult or middle-aged, brain by Fernández, Macarena Soledad, de Olmos, Soledad, Nizhnikov, Michael E., Pautassi, Ricardo Marcos

“…•Stress caused neurotoxicity in dorsal CA1 of adolescent, but not adult or aged, rats.•Ethanol caused neurotoxicity in dorsal CA2, and ventral CA3 and DG of…”
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Strain-specific programming of prenatal ethanol exposure across generations by Popoola, Daniel O, Nizhnikov, Michael E, Cameron, Nicole M

“…Abstract Behavioral consequences of prenatal alcohol exposure (PAE) can be transmitted from in utero -exposed F1 generation to their F2 offspring. This type of…”
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Prenatal ethanol exposure increases ethanol intake and reduces C-fos expression in infralimbic cortex of adolescent rats by Fabio, Maria Carolina, March, Samanta M., Molina, Juan Carlos, Nizhnikov, Michael E., Spear, Norman E., Pautassi, Ricardo Marcos

“…Prenatal ethanol exposure significantly increases later predisposition for alcohol intake, but the mechanisms associated with this phenomenon remain…”
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Influence of prenatal pre-exposure to an odor on intake behavior of an aversive solution in newborn rats by Kamenetzky, Giselle V., Suárez, Andrea B., Ifran, María Celeste, Nizhnikov, Michael E., Pautassi, Ricardo M.

“…•An odor pre-exposed in uterus can be learned by rat fetus.•This odor learning can influence the consumption of an unpalatable solution in neonate…”
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Assessing appetitive, aversive, and negative ethanol-mediated reinforcement through an immature rat model by Pautassi, Ricardo M., Nizhnikov, Michael E., Spear, Norman E.

“…The motivational effects of drugs play a key role during the transition from casual use to abuse and dependence. Ethanol reinforcement has been successfully…”
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Binge ethanol intoxication heightens subsequent ethanol intake in adolescent, but not adult, rats by Fabio, María Carolina, Nizhnikov, Michael E., Spear, Norman E., Pautassi, Ricardo Marcos

“…A question still to be answered is whether ethanol initiation has a greater effect on ethanol consumption if it occurs during adolescence than in adulthood…”
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Can low-level ethanol exposure during pregnancy influence maternal care? An investigation using two strains of rat across two generations by Popoola, Daniel O, Borrow, Amanda P, Sanders, Julia E, Nizhnikov, Michael E, Cameron, Nicole M

“…Abstract Gestational alcohol use is well documented as detrimental to both maternal and fetal health, producing an increase in offspring's tendency for…”
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Brief Prenatal Ethanol Exposure Alters Behavioral Sensitivity to the Kappa Opioid Receptor Agonist (U62,066E) and Antagonist (Nor-BNI) and Reduces Kappa Opioid Receptor Expression by Nizhnikov, Michael E., Pautassi, Ricardo M., Carter, Jenna M., Landin, Justine D., Varlinskaya, Elena I., Bordner, Kelly A., Werner, David F., Spear, Norman E.

“…Background Approximately 10 to 15% of women consume alcohol (ethanol [EtOH]) during pregnancy in the United States. Even low amounts of EtOH consumption during…”
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Age-related effects of chronic restraint stress on ethanol drinking, ethanol-induced sedation, and on basal and stress-induced anxiety response by Fernández, Macarena Soledad, Fabio, María Carolina, Miranda-Morales, Roberto Sebastián, Virgolini, Miriam B, De Giovanni, Laura N, Hansen, Cristian, Wille-Bille, Aranza, Nizhnikov, Michael E, Spear, Linda P, Pautassi, Ricardo Marcos

“…Abstract Adolescents are sensitive to the anxiolytic effect of ethanol, and evidence suggests that they may be more sensitive to stress than adults. Relatively…”
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Change in the hedonic value of an aversive stimulus in the presence of a pre-exposed odor by Kamenetzky, Giselle V, Suárez, Andrea B, Pautassi, Ricardo M, Mustaca, Alba E, Nizhnikov, Michael E

“…Abstract Rats exhibit a sensitive period from the time of birth until postnatal day 10 during which they develop preferences for odors even if those odors are…”
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Role of mu, delta and kappa opioid receptors in ethanol-reinforced operant responding in infant rats by Miranda-Morales, Roberto Sebastián, Spear, Norman E., Nizhnikov, Michael E., Molina, Juan Carlos, Abate, Paula

“…► Infant rats rapidly learn an operant task when receiving ethanol as reinforcer. ► Opioid system is involved in ethanol reinforcement during infancy. ► Mu,…”
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Prenatal ethanol exposure leads to greater ethanol-induced appetitive reinforcement by Pautassi, Ricardo M, Nizhnikov, Michael E, Spear, Norman E, Molina, Juan C

“…Abstract Prenatal ethanol significantly heightens later alcohol consumption, but the mechanisms that underlie this phenomenon are poorly understood. Little is…”
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Early maternal separation affects ethanol-induced conditioning in a nor-BNI insensitive manner, but does not alter ethanol-induced locomotor activity by Pautassi, Ricardo Marcos, Nizhnikov, Michael E., Fabio, Ma. Carolina, Spear, Norman E.

“…Early environmental stress significantly affects the development of offspring. This stress has been modeled in rats through the maternal separation (MS)…”
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Prenatal exposure to ethanol during late gestation facilitates operant self-administration of the drug in 5-day-old rats by Miranda-Morales, Roberto Sebastián, Nizhnikov, Michael E, Spear, Norman E

“…Abstract Prenatal ethanol exposure modifies postnatal affinity to the drug, increasing the probability of ethanol use and abuse. The present study tested…”
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Early role of the κ opioid receptor in ethanol-induced reinforcement by Pautassi, Ricardo Marcos, Nizhnikov, Michael E, Acevedo, Ma. Belén, Spear, Norman E

“…Abstract Effects of early ethanol exposure on later ethanol intake emphasize the importance of understanding the neurobiology of ethanol-induced reinforcement…”
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