Search Results - "Nizet, Yannick"

Differential regulation of C-terminal splice variants of the glutamate transporter GLT-1 by tumor necrosis factor-alpha in primary cultures of astrocytes by Focant, Marylène C., Goursaud, Stéphanie, Nizet, Yannick, Hermans, Emmanuel

“…► A newly developed monoclonal antibody against GLT-1b was validated. ► Expression of C-terminus splice variants of GLT-1 was examined in primary astrocytes. ►…”
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An anti-CD2 mAb induces immunosuppression and hyporesponsiveness of CD2+ human T cells in vitro by Latinne, Dominique, De La Parra, Bernardo, Nizet, Yannick, Cornet, Anne, Giovino-Barry, Valerie, Monroy, Rodney L., White-Scharf, Mary E., Bazin, Hervé

“…We describe here the potent specific immunosuppression obtained in vitro by LO-CD2a, a rat mAb directed against the human CD2 molecule. Addition of low dose…”
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Different subcellular localization and glycosylation for a functional antibody expressed in Nicotiana tabacum plants and suspension cells by De Muynck, Benoit, Navarre, Catherine, Nizet, Yannick, Stadlmann, Johannes, Boutry, Marc

“…Genes encoding the heavy and light chains of LO-BM2, a therapeutic IgG antibody, were assembled in the tandem or inverted convergent orientation and expressed…”
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A new interdigitated array microelectrode-oxide-silicon sensor with label-free, high sensitivity and specificity for fast bacteria detection by Tang, Xiaohui, Flandre, Denis, Raskin, Jean-Pierre, Nizet, Yannick, Moreno-Hagelsieb, Luis, Pampin, Rémi, Francis, Laurent A.

“…We introduce a new interdigitated array microelectrode-oxide-silicon (IDAMOS) sensor with label-free, high sensitivity and specificity for fast bacteria…”
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Two widely expressed plasma membrane H⁺-ATPase isoforms of Nicotiana tabacum are differentially regulated by phosphorylation of their penultimate threonine by Bobik, Krzysztof, Duby, Geoffrey, Nizet, Yannick, Vandermeeren, Caroline, Stiernet, Patrick, Kanczewska, Justyna, Boutry, Marc

“…The plasma membrane H⁺-ATPases PMA2 and PMA4 are the most widely expressed in Nicotiana plumbaginifolia, and belong to two different subfamilies. Both are…”
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The VPAC 2 agonist peptide histidine isoleucine (PHI) up‐regulates glutamate transport in the corpus callosum of a rat model of amyotrophic lateral sclerosis (hSOD1 G93A ) by inhibiting caspase‐3 mediated inactivation of GLT‐1a by Goursaud, Stéphanie, Focant, Marylène C., Berger, Julie V., Nizet, Yannick, Maloteaux, Jean‐Marie, Hermans, Emmanuel

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Induction of autoantibodies against mouse soluble proteins after immunization with living cells presenting the autoantigen at the cell surface in fusion with a human type 2 transmembrane protein by Lemaire, Muriel M., Vanhaudenarde, Aurélie, Nizet, Yannick, Dumoutier, Laure, Renauld, Jean-Christophe

“…Induction of autoantibodies towards immune regulatory proteins, such as cytokines or their receptors, is a powerful strategy for functional studies on the role…”
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Two widely expressed plasma membrane H+-ATPase isoforms of Nicotiana tabacum are differentially regulated by phosphorylation of their penultimate threonine: Differential regulation of H+-ATPases by Bobik, Krzysztof, Duby, Geoffrey, Nizet, Yannick, Vandermeeren, Caroline, Stiernet, Patrick, Kanczewska, Justyna, Boutry, Marc

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Inhibition of Humoral Response to Allogeneic Porcine Mesenchymal Stem Cell With 12 Days of Tacrolimus by PONCELET, Alain J, NIZET, Yannick, VERCRUYSSE, Jonathan, HIEL, Anne Lise, SALIEZ, Alain, GIANELLO, Pierre

“…In vivo studies have highlighted allogeneic mesenchymal stem-cell (MSC) immunogenicity. We investigated in vitro MSC-immunosuppressive drugs interaction and…”
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The VPAC2 agonist peptide histidine isoleucine (PHI) up‐regulates glutamate transport in the corpus callosum of a rat model of amyotrophic lateral sclerosis (hSOD1G93A) by inhibiting caspase‐3 mediated inactivation of GLT‐1a by Goursaud, Stéphanie, Focant, Marylène C., Berger, Julie V., Nizet, Yannick, Maloteaux, Jean‐Marie, Hermans, Emmanuel

“…ABSTRACT Degeneration of corpus callosum appears in patients with amyotrophic lateral sclerosis (ALS) before clinical signs of upper motor neuron death…”
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Anti-cytokine vaccines using living cells presenting endogenous cytokines in fusion with a human transmembrane protein by Lemaire, Muriel M., Vanhaudenarde, Aurélie, Nizet, Yannick, Dumoutier, Laure, Renauld, Jean-Christophe

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Antibody production by injection of living cells expressing non self antigens as cell surface type II transmembrane fusion protein by Nizet, Yannick, Gillet, Laurent, Schroeder, Hélène, Lecuivre, Corinne, Louahed, J., Renauld, J.-C., Gianello, Pierre, Vanderplasschen, Alain

“…Antigen expression and purification are laborious, time consuming and frequently difficult steps in the process of antibody production. In the present study,…”
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Natural antibody–complement dependent neutralization of bovine herpesvirus 4 by human serum by Machiels, Bénédicte, Gillet, Laurent, Nascimento Brito, Sieberth Do, Drion, Pierre, Delforge, Cédric, Nizet, Yannick, Gianello, Pierre, Bona, Christophe, Costes, Bérénice, Markine-Goriaynoff, Nicolas, Vanderplasschen, Alain

“…In contrast to most gammaherpesviruses, Bovine herpesvirus 4 (BoHV-4) has a broad range of host species both in vitro and in vivo. Several in vitro studies…”
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Cell-mediated cytotoxicity to porcine aortic endothelial cells is not dependent on galactosyl residues when baboon peripheral blood lymphocytes are previously primed with pig xenoantigens by DEHOUX, Jean-Paul, NIZET, Yannick, DE LA PARRA, Bernardo, LECUIVRE, Corinne, VERGAUWEN, Martial, BAZIN, Hervé, LATINNE, Dominique, GIANELLO, Pierre

“…In the pig-to-baboon model, acute vascular rejection remains the main hurdle for successful long-term xenograft survival. The production of galactosyl knockout…”
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The experimental (in vitro) and clinical (in vivo) immunosuppressive effects of a rat IgG2b anti-human CD2 mAb, LO-CD2a/BTI-322 by NIZET, Y, AZIZ ALAMI CHENTOUFI, BAZIN, H, LATINNE, D, DE LA PARRA, B, LEWALLE, P, ROUAS, R, CORNET, A, BESSE, T, MOURAD, M, MALAISE, J, SQUIFFLET, J.-P

“…CD2 is a cell surface glycoprotein expressed on most human T cells and natural killer (NK) cells, working as a cell adhesion and costimulatory molecule. The…”
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DIFFERENTIAL EFFECTS OF INJECTIONS OF ANTI-?? AND ANTI-?? MONOCLONAL ANTIBODIES ON B-CELL POPULATIONS IN ADULT MICE: Regulation of Xenoreactive Natural Antibody-Producing Cells1 by Chentoufi, Aziz Alami, Nizet, Yannick, Havaux, Xavier, De La Parra, Bernardo, Cormont, Fran??oise, Hermans, Dominique, Bazin, Herv??, Latinne, Dominique

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THE EXPERIMENTAL (IN VITRO) AND CLINICAL (IN VIVO) IMMUNOSUPPRESSIVE EFFECTS OF A RAT IgG2b ANTI-HUMAN CD2 mAb, LO-CD2a/BTI-3221 by Nizet, Yannick, Chentoufi, Aziz Alami, de la Parra, Bernardo, Lewalle, Philippe, Rouas, Redouane, Cornet, Anne, Besse, Tatianna, Mourad, Michel, Malaise, Jacques, Squifflet, Jean-Paul, Bazin, Herv??, Latinne, Dominique

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An anti-CD2 mAb induces immunosuppression and hyporesponsiveness of CD2positive human T cells in vitro by Latinne, Dominique, De La Parra, Bernardo, Nizet, Yannick, Cornet, Anne

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Differential effects of injections of anti-μ and anti-δ monoclonal antibodies on B-cell populations in adult mice: Regulation of xenoreactive natural antibody-producing cells by AZIZ ALAMI CHENTOUFI, NIZET, Y, HAVAUX, X, DE LA PARRA, B, CORMONT, F, HERMANS, D, BAZIN, H, LATINNE, D

“…The depletion of differential B cell and xenoreactive natural antibodies (XNA) by anti-delta and anti-mu injections was analyzed in adult mice. Sequential…”
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B-Cell Suppression in Adult Mice Injected with Anti-δ Followed by Anti-μ mAb by Alami Chentoufi, Aziz, Nizet, Yannick, Havaux, Xavier, Nisol, Françoise, Bazin, Hervé, Latinne, Dominique

“…Cross-linking of surface IgM or IgD B-cell receptors (BCR) with appropriate anti-Ig antibodies induces IgMhigh or IgDhigh B-cell depletion, respectively. The…”
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