Search Results - "Niyongere, Sandrine"

Check(point) or checkmate for acute myeloid leukemia? by Niyongere, Sandrine, Rapoport, Aaron P

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Biology and prognostic impact of clonal plasmacytoid dendritic cells in chronic myelomonocytic leukemia by Lucas, Nolwenn, Duchmann, Matthieu, Rameau, Philippe, Noël, Floriane, Michea, Paula, Saada, Véronique, Kosmider, Olivier, Pierron, Gérard, Fernandez-Zapico, Martin E, Howard, Matthew T., King, Rebecca L., Niyongere, Sandrine, Diop, M’boyba Khadija, Fenaux, Pierre, Itzykson, Raphael, Willekens, Christophe, Ribrag, Vincent, Fontenay, Michaela, Padron, Eric, Soumelis, Vassili, Droin, Nathalie, Patnaik, Mrinal M, Solary, Eric

“…Islands of CD123 high cells have been commonly described in the bone marrow of patients with chronic myelomonocytic leukemia (CMML). Using a multiparameter…”
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Olanzapine within steroid-sparing antiemetic regimen to prevent chemotherapy-induced nausea and vomiting in patients with acute leukemia receiving multi-day intensive chemotherapy by Hsu, Grace, Bernhardi, Ciera, Lawson, Justin, Duong, Vu H., Emadi, Ashkan, Niyongere, Sandrine, Duffy, Alison

“…Introduction Olanzapine use for chemotherapy-induced nausea and vomiting (CINV) in hematological malignancies, for multi-day chemotherapy, and with a…”
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Venetoclax and pegcrisantaspase for complex karyotype acute myeloid leukemia by Emadi, Ashkan, Kapadia, Bandish, Bollino, Dominique, Bhandary, Binny, Baer, Maria R., Niyongere, Sandrine, Strovel, Erin T., Kaizer, Hannah, Chang, Elizabeth, Choi, Eun Yong, Ma, Xinrong, Tighe, Kayla M., Carter-Cooper, Brandon, Moses, Blake S., Civin, Curt I., Mahurkar, Anup, Shetty, Amol C., Gartenhaus, Ronald B., Kamangar, Farin, Lapidus, Rena G.

“…Complex karyotype acute myeloid leukemia (CK-AML) has a dismal outcome with current treatments, underscoring the need for new therapies. Here, we report…”
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Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML by Yoshimi, Akihide, Balasis, Maria E., Vedder, Alexis, Feldman, Kira, Ma, Yan, Zhang, Hailing, Lee, Stanley Chun-Wei, Letson, Christopher, Niyongere, Sandrine, Lu, Sydney X., Ball, Markus, Taylor, Justin, Zhang, Qing, Zhao, Yulong, Youssef, Salma, Chung, Young Rock, Zhang, Xiao Jing, Durham, Benjamin H., Yang, Wendy, List, Alan F., Loh, Mignon L., Klimek, Virginia, Berger, Michael F., Stieglitz, Elliot, Padron, Eric, Abdel-Wahab, Omar

“…Chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML) are myelodysplastic syndrome (MDS)/myeloproliferative neoplasm (MPN) overlap…”
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TGF-beta promotes Th17 cell development through inhibition of SOCS3 by Qin, Hongwei, Wang, Lanfang, Feng, Ting, Elson, Charles O, Niyongere, Sandrine A, Lee, Sun Jung, Reynolds, Stephanie L, Weaver, Casey T, Roarty, Kevin, Serra, Rosa, Benveniste, Etty N, Cong, Yingzi

“…TGF-beta, together with IL-6 and IL-21, promotes Th17 cell development. IL-6 and IL-21 induce activation of STAT3, which is crucial for Th17 cell…”
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Expression and Functional Significance of SOCS-1 and SOCS-3 in Astrocytes by Qin, Hongwei, Niyongere, Sandrine A, Lee, Sun Jung, Baker, Brandi J, Benveniste, Etty N

“…Astrocytes play a number of important physiological roles in CNS homeostasis. Inflammation stimulates astrocytes to secrete cytokines and chemokines that guide…”
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Molecular Mechanism of Lipopolysaccharide-Induced SOCS-3 Gene Expression in Macrophages and Microglia by Qin, Hongwei, Roberts, Kevin L, Niyongere, Sandrine A, Cong, Yingzi, Elson, Charles O, Benveniste, Etty N

“…Immunological activation of macrophages/microglia within the CNS leads to the production of cytokines and chemokines that ultimately impact on glial and…”
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Venous thromboembolism incidence and risk factors in adults with acute lymphoblastic leukemia treated with and without pegylated E. coli asparaginase-containing regimens by Kashanian, Sarah M., Holtzman, Noa G., Patzke, Ciera L., Cornu, Jonathan, Duffy, Alison, Koka, Madhurima, Niyongere, Sandrine, Duong, Vu H., Baer, Maria R., Apata, Jummai, Kamangar, Farin, Emadi, Ashkan

“…Purpose Asparaginases, key agents in treatment of acute lymphoblastic leukemia (ALL), are associated with venous thromboembolism (VTE). While risks of…”
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Outcomes of Newly Diagnosed Acute Myeloid Leukemia Patients Treated With Hypomethylating Agents With or Without Venetoclax: A Propensity Score-Adjusted Cohort Study by Mustafa Ali, Moaath K, Corley, Elizabeth M, Alharthy, Hanan, Kline, Kathryn A F, Law, Jennie Y, Lee, Seung Tae, Niyongere, Sandrine, Duong, Vu H, Emadi, Ashkan, Baer, Maria R

“…There is a deficiency of real-world data on the impact of combining venetoclax (VEN) with hypomethylating agents (HMAs) in newly diagnosed acute myeloid…”
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Frontline Blinatumomab in Older Adults with Philadelphia Chromosome-Negative B-Cell Acute Lymphoblastic Leukemia by Niyongere, Sandrine, Sanchez-Petitto, Gabriela, Masur, Jack, Baer, Maria R, Duong, Vu H, Emadi, Ashkan

“…Outcomes of acute lymphoblastic leukemia (ALL) in older adults treated with chemotherapy are poor. The CD19/CD3 bispecific T-cell engager (BiTE) antibody…”
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Impact of IDH1 c.315C>T SNP on Outcomes in Acute Myeloid Leukemia: A Propensity Score-Adjusted Cohort Study by Corley, Elizabeth M, Mustafa Ali, Moaath K, Alharthy, Hanan, Kline, Kathryn A F, Sewell, Danielle, Law, Jennie Y, Lee, Seung Tae, Niyongere, Sandrine, Duong, Vu H, Baer, Maria R, Emadi, Ashkan

“…Acute myeloid leukemia (AML) is the common type of acute leukemia in adults. Definitive prognostic significance of variants of unknown significance lacks for…”
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Impact of FLT3 -ITD Insertion Length on Outcomes in Acute Myeloid Leukemia: A Propensity Score-Adjusted Cohort Study by Corley, Elizabeth M, Mustafa Ali, Moaath K, Alharthy, Hanan, Kline, Kathryn A F, Sewell, Danielle, Law, Jennie Y, Lee, Seung Tae, Niyongere, Sandrine, Duong, Vu H, Baer, Maria R, Emadi, Ashkan

“…The prognostic significance of the length of internal tandem duplication (ITD) insertions in mutant FLT3 genes in acute myeloid leukemia (AML) is…”
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Therapy-related B-lymphoblastic leukemia after multiple myeloma by Kallen, Michael E., Koka, Rima, Singh, Zeba N., Ning, Yi, Kocoglu, Mehmet H., Badros, Ashraf Z., Niyongere, Sandrine, Duong, Vu H., Emadi, Ashkan, Baer, Maria R.

“…New therapies for multiple myeloma have improved outcomes, but are associated with therapy-related hematologic malignancies. We report eight patients with…”
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Hypomethylating Agent Therapy for Chronic Myelomonocytic Leukemia Does Not Impact Acute Myeloid Leukemia Transformation or Survival by Niyongere, Sandrine, Kathari, Yamini, Singh, Zeba, Vannorsdall, Emily J., Emadi, Ashkan, Doung, Vu, Baer, Maria R.

“…Background: Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with features of both myeloproliferative neoplasm and…”
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Prognostication of the 2016-Who AML with Myelodysplasia-Related Changes Subclass and Mutations in MDS-Related Genes Using the 2022 European Leukemianet Risk Classification: A Retrospective Study by Alkaabba, Fahad, Williams, Matthew, Corley, Elizabeth, Alharthy, Hanan, Kline, Kathryn A.F., Lee, Seung Tae, Kallen, Michael, Niyongere, Sandrine, Duong, Vu H., Baer, Maria R., Mustafa Ali, Moaath K.

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Impact of KRAS and NRAS mutations on outcomes in acute myeloid leukemia by Mustafa Ali, Moaath K., Williams, Matthew T., Corley, Elizabeth M., AlKaabba, Fahad, Niyongere, Sandrine

“…The prognostic significance of RAS mutations in AML is poorly understood. In this ambispective cohort study of 239 newly-diagnosed AML patients at the…”
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Overcoming Venetoclax (Ven) Resistance through Glutamine (Gln) Depletion: Final Analysis of the Phase 1 Trial of Ven and Pegcrisantaspase (PegC) Combination in Relapsed and Refractory (R/R) Acute Myeloid Leukemia (AML) by Liu, Yuchen, Bollino, Dominique, Bah, Osman M, Strovel, Erin T, Zarrabi, Jinoos, Philip, Sunita, Mostafa, Ezzat, Lapidus, Rena G, Baer, Maria R., Niyongere, Sandrine, Duong, Vu H., Dougherty, Christine C, Caprinolo, Katherine, Emadi, Ashkan

“…Background: Ven-based therapies have been an advancement in the front-line treatment of AML; however development of resistance is common and the efficacy of…”
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Phase I Clinical Trial of DNA Methyltransferase Inhibitor Decitabine and PARP Inhibitor Talazoparib Combination Therapy in Relapsed/Refractory Acute Myeloid Leukemia by Baer, Maria R, Kogan, Aksinija A, Bentzen, Søren M, Mi, Tian, Lapidus, Rena G, Duong, Vu H, Emadi, Ashkan, Niyongere, Sandrine, O'Connell, Casey L, Youngblood, Benjamin A, Baylin, Stephen B, Rassool, Feyruz V

“…Patients with acute myeloid leukemia (AML) unfit for, or resistant to, intensive chemotherapy are often treated with DNA methyltransferase inhibitors (DNMTi)…”
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Immunotherapy combination strategies (non-chemotherapy) in non-small cell lung cancer by Niyongere, Sandrine, Saltos, Andreas, Gray, Jhanelle E

“…Immune checkpoint inhibitors enhance the activation and antitumor activity of the immune system, resulting in durable response rates in a select group of…”
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