Search Results - "Niven, M."

Nebulised 7% hypertonic saline improves lung function and quality of life in bronchiectasis by Kellett, Fiona, Robert, Niven M

“…Summary Sputum retention is a distressing feature of non-cystic fibrosis bronchiectasis and has been shown to contribute to the vicious cycle of infection seen…”
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Comorbidity in severe asthma requiring systemic corticosteroid therapy: cross-sectional data from the Optimum Patient Care Research Database and the British Thoracic Difficult Asthma Registry by Sweeney, Joan, Patterson, Chris C, Menzies-Gow, Andrew, Niven, Rob M, Mansur, Adel H, Bucknall, Christine, Chaudhuri, Rekha, Price, David, Brightling, Chris E, Heaney, Liam G

“…To determine the prevalence of systemic corticosteroid-induced morbidity in severe asthma. Cross-sectional observational study. The primary care Optimum…”
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Fungi and allergic lower respiratory tract diseases by Knutsen, Alan P., MD, Bush, Robert K., MD, Demain, Jeffrey G., MD, Denning, David W., FRCP, FMedSci, Dixit, Anupma, PhD, MPH, Fairs, Abbie, MD, Greenberger, Paul A., MD, Kariuki, Barbara, BS, MPH, Kita, Hirohito, MD, Kurup, Viswanath P., PhD, Moss, Richard B., MD, Niven, Robert M., MD, Pashley, Catherine H., MD, Slavin, Raymond G., MD, Vijay, Hari M., PhD, MPH, Wardlaw, Andrew J., MD

“…Asthma is a common disorder that in 2009 afflicted 8.2% of adults and children, 24.6 million persons, in the United States. In patients with moderate and…”
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Statistical cluster analysis of the British Thoracic Society Severe refractory Asthma Registry: clinical outcomes and phenotype stability by Newby, Chris, Heaney, Liam G, Menzies-Gow, Andrew, Niven, Rob M, Mansur, Adel, Bucknall, Christine, Chaudhuri, Rekha, Thompson, John, Burton, Paul, Brightling, Chris

“…Severe refractory asthma is a heterogeneous disease. We sought to determine statistical clusters from the British Thoracic Society Severe refractory Asthma…”
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The link between fungi and severe asthma: a summary of the evidence by Denning, D. W, O'Driscoll, B. R, Hogaboam, C. M, Bowyer, P, Niven, R. M

“…There is current evidence to demonstrate a close association between fungal sensitisation and asthma severity. Whether such an association is causal remains to…”
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Refractory asthma in the UK: cross-sectional findings from a UK multicentre registry by Heaney, Liam G, Brightling, Chris E, Menzies-Gow, Andrew, Stevenson, Michael, Niven, Rob M

“…Refractory asthma represents a significant unmet clinical need where the evidence base for the assessment and therapeutic management is limited. The British…”
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Asthma Control during the Year after Bronchial Thermoplasty by Cox, Gerard, Thomson, Neil C, Rubin, Adalberto S, Niven, Robert M, Corris, Paul A, Siersted, Hans Christian, Olivenstein, Ronald, Pavord, Ian D, McCormack, David, Chaudhuri, Rekha, Miller, John D, Laviolette, Michel

“…Asthmatic exacerbations result in part from constriction of airway smooth muscle. In this controlled trial, the use of bronchoscopically delivered thermoplasty…”
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Safety and Efficacy of Bronchial Thermoplasty in Symptomatic, Severe Asthma by Pavord, Ian D, Cox, Gerard, Thomson, Neil C, Rubin, Adalberto S, Corris, Paul A, Niven, Robert M, Chung, Kian F, Laviolette, Michel, RISA Trial Study Group

“…Bronchial thermoplasty (BT) is designed to reduce airway smooth muscle and improve asthma control. This study was conducted to determine the safety and…”
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Does BCG vaccination protect against childhood asthma? Final results from the Manchester Community Asthma Study retrospective cohort study and updated systematic review and meta-analysis by Linehan, Mary F., PhD, Nurmatov, Ulugbek, PhD, Frank, Timothy L., MD, Niven, Robert M., MD, Baxter, David N., PhD, Sheikh, Aziz, MD

“…Background The Manchester Community Asthma Study (MANCAS) found a protective effect against the risk of wheeze at age 6 to 11 years for children given neonatal…”
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Clinical outcomes and inflammatory biomarkers in current smokers and exsmokers with severe asthma by Thomson, Neil C., MD, Chaudhuri, Rekha, MD, Heaney, Liam G., MD, Bucknall, Christine, FRCP, Niven, Robert M., MD, Brightling, Christopher E., PhD, Menzies-Gow, Andrew N., MRCP, Mansur, Adel H., FRCP, McSharry, Charles, PhD

“…Background Clinical outcomes are worse in current smokers and exsmokers with mild-to-moderate asthma compared with never smokers, but little is known about the…”
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Efficacy and safety of bronchial thermoplasty in clinical practice: a prospective, longitudinal, cohort study using evidence from the UK Severe Asthma Registry by Burn, Julie, Sims, Andrew J, Patrick, Hannah, Heaney, Liam G, Niven, Robert M

“…ObjectivesUse data from the UK Severe Asthma Registry (UKSAR) to assess the efficacy and safety of bronchial thermoplasty (BT) in routine UK clinical practice…”
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Long-term (5 year) safety of bronchial thermoplasty: Asthma Intervention Research (AIR) trial by Thomson, Neil C, Rubin, Adalberto S, Niven, Robert M, Corris, Paul A, Siersted, Hans Christian, Olivenstein, Ronald, Pavord, Ian D, McCormack, David, Laviolette, Michel, Shargill, Narinder S, Cox, Gerard

“…Bronchial thermoplasty (BT) is a bronchoscopic procedure that improves asthma control by reducing excess airway smooth muscle. Treated patients have been…”
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Impact of omalizumab on treatment of severe allergic asthma in UK clinical practice: a UK multicentre observational study (the APEX II study) by Niven, Robert M, Saralaya, Dinesh, Chaudhuri, Rekha, Masoli, Matthew, Clifton, Ian, Mansur, Adel H, Hacking, Victoria, McLain-Smith, Susan, Menzies-Gow, Andrew

“…ObjectiveTo describe the impact of omalizumab on asthma management in patients treated as part of normal clinical practice in the UK National Health Service…”
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Diminished airway macrophage expression of the Axl receptor tyrosine kinase is associated with defective efferocytosis in asthma by Grabiec, Aleksander M., PhD, Denny, Nicholas, BA, BMBCh, Doherty, John A., BSc, Happonen, Kaisa E., PhD, Hankinson, Jenny, PhD, Connolly, Emma, MSc, Fife, Mark E., BSc, Fujimori, Toshifumi, PhD, Fujino, Naoya, MD, PhD, Goenka, Anu, MD, Holden, Susan, MSc, Tavernier, Gaël, PhD, Shah, Rajesh, FRCS, Cook, Peter C., PhD, MacDonald, Andrew S., PhD, Niven, Robert M., MD, Dahlbäck, Björn, PhD, Fowler, Stephen J., MD, Simpson, Angela, MD, PhD, Hussell, Tracy, PhD

“…The apoptotic cell recognition receptor Axl is highly expressed on human airway/alveolar macrophages, its expression is driven by the lung microenvironment and…”
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Comparison of skin prick tests with specific serum immunoglobulin E in the diagnosis of fungal sensitization in patients with severe asthma by O'Driscoll, B. R., Powell, G., Chew, F., Niven, R. M., Miles, J. F., Vyas, A., Denning, D. W.

“…Summary Background It has been shown that patients with allergic bronchopulmonary aspergillosis (ABPA) and patients with severe asthma with fungal…”
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Reduction in peripheral blood eosinophil counts after bronchial thermoplasty by Ryan, Dorothy M., MD, Fowler, Stephen J., MD, Niven, Robert M., MD

“…Emergency prednisolone courses were significantly reduced after BT, from a median of 3 per year before BT to 0 per year after BT (P = .01, Table I)…”
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Safety of bronchial thermoplasty in patients with severe refractory asthma by Pavord, Ian D., MD, Thomson, Neil C., MD, Niven, Robert M., MD, Corris, Paul A., MD, Chung, Kian Fan, MD, Cox, Gerard, MB, Armstrong, Brian, MS, Shargill, Narinder S., PhD, Laviolette, Michel, MD

“…Abstract Background Patients with severe refractory asthma treated with bronchial thermoplasty (BT), a bronchoscopic procedure that improves asthma control by…”
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Absence of K13 gene mutations among artesunate/sulfadoxine-pyrimethamine treatment failures of Sudanese Plasmodium falciparum isolates from Damazin, southeast Sudan by Abdel Hamid, Muzamil M, Abdallah, Walla M E, Hussien, Maazza, Mohammed, Niven M, Malik, Elfatih M, Ahmed, Mohamed E, Mohamed, Abdelrahim O

“…The emergence of resistant parasites to artemisinin poses a threat to malaria treatment. The study aimed to investigate K13 gene mutations in Plasmodium…”
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A novel potential therapy for vascular diseases: Blood-derived stem/progenitor cells specifically activated by dendritic cells by Porat, Y, Niven, M, Sivak, G, Kafri, E, Moshe, M, Frogel, M, Belkin, M

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Immunoglobulin E in irritable bowel syndrome: another target for treatment? A case report and literature review by Pearson, James S., Niven, Robert M., Meng, Jie, Atarodi, Sima, Whorwell, Peter J.

“…Irritable bowel syndrome (IBS) is notoriously difficult to treat and this situation is unlikely to change until the pathophysiology is better understood. There…”
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