Search Results - "Nivarthi, H"

Autocrine WNT2 signaling in fibroblasts promotes colorectal cancer progression by Kramer, N, Schmöllerl, J, Unger, C, Nivarthi, H, Rudisch, A, Unterleuthner, D, Scherzer, M, Riedl, A, Artaker, M, Crncec, I, Lenhardt, D, Schwarz, T, Prieler, B, Han, X, Hengstschläger, M, Schüler, J, Eferl, R, Moriggl, R, Sommergruber, W, Dolznig, H

“…The canonical WNT signaling pathway is crucial for intestinal stem cell renewal and aberrant WNT signaling is an early event in colorectal cancer (CRC)…”
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Thrombopoietin receptor is required for the oncogenic function of CALR mutants by Nivarthi, H, Chen, D, Cleary, C, Kubesova, B, Jäger, R, Bogner, E, Marty, C, Pecquet, C, Vainchenker, W, Constantinescu, S N, Kralovics, R

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Pathologic activation of thrombopoietin receptor and JAK2-STAT5 pathway by frameshift mutants of mouse calreticulin by Balligand, T, Achouri, Y, Pecquet, C, Chachoua, I, Nivarthi, H, Marty, C, Vainchenker, W, Plo, I, Kralovics, R, Constantinescu, S N

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IGFBP7, a novel tumor stroma marker, with growth-promoting effects in colon cancer through a paracrine tumor–stroma interaction by Rupp, C, Scherzer, M, Rudisch, A, Unger, C, Haslinger, C, Schweifer, N, Artaker, M, Nivarthi, H, Moriggl, R, Hengstschläger, M, Kerjaschki, D, Sommergruber, W, Dolznig, H, Garin-Chesa, P

“…The activated tumor stroma participates in many processes that control tumorigenesis, including tumor cell growth, invasion and metastasis. Cancer-associated…”
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Stat5 gene dosage in T cells modulates CD8+ T‐cell homeostasis and attenuates contact hypersensitivity response in mice by Nivarthi, H., Prchal‐Murphy, M., Swoboda, A., Hager, M., Schlederer, M., Kenner, L., Tuckermann, J., Sexl, V., Moriggl, R., Ermakova, O.

“…Background Contact hypersensitivity assay (CHS) faithfully models human allergies. The Stat5 transcription factors are essential for both lymphocyte…”
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Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants by Pecquet, Christian, Chachoua, Ilyas, Roy, Anita, Balligand, Thomas, Vertenoeil, Gaëlle, Leroy, Emilie, Albu, Roxana-Irina, Defour, Jean-Philippe, Nivarthi, Harini, Hug, Eva, Xu, Erica, Ould-Amer, Yasmine, Mouton, Céline, Colau, Didier, Vertommen, Didier, Shwe, Myat Marlar, Marty, Caroline, Plo, Isabelle, Vainchenker, William, Kralovics, Robert, Constantinescu, Stefan N.

“…Calreticulin (CALR) +1 frameshift mutations in exon 9 are prevalent in myeloproliferative neoplasms. Mutant CALRs possess a new C-terminal sequence rich in…”
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Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis by Grabner, Beatrice, Schramek, Daniel, Mueller, Kristina M., Moll, Herwig P., Svinka, Jasmin, Hoffmann, Thomas, Bauer, Eva, Blaas, Leander, Hruschka, Natascha, Zboray, Katalin, Stiedl, Patricia, Nivarthi, Harini, Bogner, Edith, Gruber, Wolfgang, Mohr, Thomas, Zwick, Ralf Harun, Kenner, Lukas, Poli, Valeria, Aberger, Fritz, Stoiber, Dagmar, Egger, Gerda, Esterbauer, Harald, Zuber, Johannes, Moriggl, Richard, Eferl, Robert, Győrffy, Balázs, Penninger, Josef M., Popper, Helmut, Casanova, Emilio

“…STAT3 is considered to play an oncogenic role in several malignancies including lung cancer; consequently, targeting STAT3 is currently proposed as therapeutic…”
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PS1436 IFN‐Α TREATMENT NORMALIZES THE PLATELET COUNTS AND REDUCES QUIESCENT STEM CELLS IN A CALR‐DEL52 TRANSGENIC MOUSE MODEL, IN VIVO by Nivarthi, H., Majoros, A., Hug, E., Jia, R., Jäger, R., Achyutuni, S., Milosavljevic, N., Stuecklschwaiger, D., Holly, R., Grabner, B., Rosebrock, F., Xu, E., Weinzierl, J., Fuchs, E., Lee, S.‐J., Lee, C.W., Kralovics, R.

“…Background: Treatment options for Myeloproliferative Neoplasms (MPN) have mainly been limited to disease managing risk of thromboembolic events and long‐term…”
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