Search Results - "Niu, Yimin"

Editorial: Pathogenic mechanisms, injury biomarkers, prophylaxis and treatment strategy of drug-induced nephrotoxicity by Jiao, Guozheng, Niu, Yimin, Wang, Bin

“…Graphical Abstract…”
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Kampo Formulations, Chotosan, and Yokukansan, for Dementia Therapy: Existing Clinical and Preclinical Evidence by Matsumoto, Kinzo, Zhao, Qi, Niu, Yimin, Fujiwara, Hironori, Tanaka, Ken, Sasaki-Hamada, Sachie, Oka, Jun-Ichiro

“…Cognitive deficits and behavioral and psychological symptoms of dementia (BPSD) are typical features of patients with dementia such as Alzheimer’s disease…”
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Chotosan, a Kampo Formula, Ameliorates Hippocampal LTD and Cognitive Deficits in Juvenile-Onset Diabetes Rats by Sasaki-Hamada, Sachie, Tamaki, Keita, Otsuka, Hayuma, Ueno, Tatsuto, Sacai, Hiroaki, Niu, Yimin, Matsumoto, Kinzo, Oka, Jun-Ichiro

“…Childhood-onset type 1 diabetes is associated with modest impairments in cognition and has an elevated risk of cognitive decline. Our previous study showed…”
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Size shrinkable drug delivery nanosystems and priming the tumor microenvironment for deep intratumoral penetration of nanoparticles by Niu, Yimin, Zhu, Jianhua, Li, Yang, Shi, Huihui, Gong, Yaxiang, Li, Rui, Huo, Qiang, Ma, Tao, Liu, Yang

“…The penetration of nanomedicine into solid tumor still constitutes a great challenge for cancer therapy, which lead to the failure of thorough clearance of…”
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Chotosan ameliorates cognitive and emotional deficits in an animal model of type 2 diabetes: possible involvement of cholinergic and VEGF/PDGF mechanisms in the brain by Zhao, Qi, Niu, Yimin, Matsumoto, Kinzo, Tsuneyama, Koichi, Tanaka, Ken, Miyata, Takeshi, Yokozawa, Takako

“…Diabetes is one of the risk factors for cognitive deficits such as Alzheimer's disease. To obtain a better understanding of the anti-dementia effect of…”
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Regulation of Synovial Macrophages Polarization by Mimicking Efferocytosis for Therapy of Osteoarthritis by Yang, Hongbin, Yu, Zhenyan, Ji, Shuaishuai, Yan, Jie, kong, Yan, Huo, Qiang, Zhang, Zhijun, Niu, Yimin, Liu, Yang

“…The progression of osteoarthritis is associated with chronic synovitis caused by synovial macrophage infiltration and proinflammatory M1 polarization…”
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Intervention with the Bone-Associated Tumor Vicious Cycle through Dual-Protein Therapeutics for Treatment of Skeletal-Related Events and Bone Metastases by Niu, Yimin, Yang, Hongbin, Yu, Zhenyan, Gao, Cuicui, Ji, Shuaishuai, Yan, Jie, Han, Lei, Huo, Qiang, Xu, Ming, Liu, Yang

“…Bone metastasis is a common metastasis site such as lung cancer, prostate cancer, and other malignant tumors. The occurrence of bone metastases of lung cancer…”
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Targeting bone microenvironments for treatment and early detection of cancer bone metastatic niches by Yang, Hongbin, Yu, Zhenyan, Ji, Shuaishuai, Huo, Qiang, Yan, Juanzhu, Gao, Yue, Niu, Yimin, Xu, Ming, Liu, Yang

“…Bone tissues are the main metastatic sites of many cancers, and bone metastasis is an important cause of death. When bone metastasis occurs, dynamic…”
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Tailor-made legumain/pH dual-responsive doxorubicin prodrug-embedded nanoparticles for efficient anticancer drug delivery and in situ monitoring of drug release by Li, Yang, Niu, Yimin, Zhu, Jianhua, Gao, Cuicui, Xu, Qunwei, He, Zhiyu, Chen, Dawei, Xu, Ming, Liu, Yang

“…Legumain enzyme is a well-conserved lysosomal cysteine protease and is over-expressed in many tumor cells and tumor stromal cells and exhibits higher protease…”
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Abstract 6237: Bone-targeted nanoparticle containing protein therapeutics as an effective delivery system for bone metastasis by Niu, Yimin, Gao, Cuicui, Yang, Hongbin, Huo, Qiang, Wang, Andrew, Xu, Ming, Liu, Yang

“…Abstract Background: Protein drugs are one of the most promising new areas in drug research and development, however, great challenges are still faced in the…”
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Construction and evaluation of detachable bone-targeting MOF carriers for the delivery of proteasome inhibitors by Yang, Hongbing, Yu, Zhenyan, Ji, Shuaishuai, Yan, Jie, Han, Lei, Liu, Yang, Wang, Yanjuan, Niu, Yimin, Huo, Qiang, Xu, Ming

“…Tumor bone metastasis is an important cause of tumor recurrence and death. Although bone-targeting nanoparticles decorated with targeting ligands have shown…”
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pH-triggered surface charge-switchable polymer micelles for the co-delivery of paclitaxel/disulfiram and overcoming multidrug resistance in cancer by Huo, Qiang, Zhu, Jianhua, Niu, Yimin, Shi, Huihui, Gong, Yaxiang, Li, Yang, Song, Huihui, Liu, Yang

“…Multidrug resistance (MDR) remains a major challenge for providing effective chemotherapy for many cancer patients. To address this issue, we report an…”
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Formulation design and characterization of silymarin liposomes for enhanced antitumor activity by Ke, Zhongcheng, Cheng, Xiaoling, Yang, Huimin, Niu, Yimin, Cheng, Xu, Ye, Ting, Sun, Guangying, Cheng, Ziyang, Sun, Yinyu

“…Liposomes, a nanoscale carrier, plays an important role in the delivery of drug, affects the in vivo efficacy of drugs. In this paper, silymarin(SM)-loaded…”
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A PZT micro-actuated suspension for high TPI hard disk servo systems by Yimin Niu, Wei Guo, Guoxiao Guo, Eng Hong Ong, Sivadasan, K.K., Huang, T.

“…A piezoelectrically actuated suspension for high TPI (tracks per inch) hard disk drives is presented. Two reinforced piezoelectric microactuators, placed in…”
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Programmed co-delivery of platinum nanodrugs and gemcitabine by a clustered nanocarrier for precision chemotherapy for NSCLC tumors by Shi, Huihui, Xu, Ming, Zhu, Jianhua, Li, Yang, He, Zhiyu, Zhang, Yuxia, Xu, Qunwei, Niu, Yimin, Liu, Yang

“…Recently, ultra-small platinum nanoparticles (USPtNs) have been found that can kill cancer cells by leaching Pt ions into acidic organelles, such as cell…”
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Possible involvement of VEGF signaling system in rescuing effect of endogenous acetylcholine on NMDA-induced long-lasting hippocampal cell damage in organotypic hippocampal slice cultures by Inada, Chikako, Niu, Yimin, Matsumoto, Kinzo, Le, Xoan Thi, Fujiwara, Hironori

“…•Tacrine (THA) rescued hippocampal cells from NMDA-induced delayed damage in slice cultures.•The effect of THA was blocked by inhibition of PKC and VEGF…”
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Chemical profiling with HPLC-FTMS of exogenous and endogenous chemicals susceptible to the administration of chotosan in an animal model of type 2 diabetes-induced dementia by Niu, Yimin, Li, Feng, Inada, Chikako, Tanaka, Ken, Watanabe, Shiro, Fujiwara, Hironori, Sasaki-Hamada, Sachie, Oka, Jun-Ichiro, Matsumoto, Kinzo

“…•Chotosan (CTS) reportedly has a tacrine-like antidementia effect in a diabetes model.•Plasma and brain samples of the model were analyzed by HPLC-FTMS after…”
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Kampo Formulations, Chotosan, and Yokukansan, for Dementia Therapy: Existing Clinical and Preclinical Evidence by Kinzo Matsumoto, Qi Zhao, Yimin Niu, Hironori Fujiwara, Ken Tanaka, Sachie Sasaki-Hamada, Jun-Ichiro Oka

“…[Abstract.] Cognitive deficits and behavioral and psychological symptoms of dementia (BPSD) are typical features of patients with dementia such as Alzheimer's…”
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