Search Results - "Niu, Xuyan"
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Traditional Chinese Medicine-Based Network Pharmacology Could Lead to New Multicompound Drug Discovery
Published in Evidence-based complementary and alternative medicine (01-01-2012)“…Current strategies for drug discovery have reached a bottleneck where the paradigm is generally “one gene, one drug, one disease.” However, using holistic and…”
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2
Serum Metabolic Signatures of Four Types of Human Arthritis
Published in Journal of proteome research (02-08-2013)“…Similar symptoms of the different types of arthritis have continued to confound the clinical diagnosis and represent a clinical dilemma making treatment…”
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3
Cytokine Imbalance as a Common Mechanism in Both Psoriasis and Rheumatoid Arthritis
Published in Mediators of Inflammation (01-01-2017)“…Psoriasis (PS) and rheumatoid arthritis (RA) are immune-mediated inflammatory diseases. Previous studies showed that these two diseases had a common…”
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4
The Potential Biomarkers to Identify the Development of Steatosis in Hyperuricemia
Published in PloS one (18-02-2016)“…Hyperuricemia (HU) often progresses to combine with non-alcoholic fatty liver disease (NAFLD) in the clinical scenario, which further exacerbates metabolic…”
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Anti-oxidative and TNF-α suppressive activities of puerarin derivative (4AC) in RAW264.7 cells and collagen-induced arthritic rats
Published in European journal of pharmacology (01-09-2011)“…Puerarin is a major active ingredient extracted from the root of P. lobata, a traditional Chinese herb, and possesses anti-oxidative and anti-inflammatory…”
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6
Differential Amino Acid, Carbohydrate and Lipid Metabolism Perpetuations Involved in a Subtype of Rheumatoid Arthritis with Chinese Medicine Cold Pattern
Published in International journal of molecular sciences (01-10-2016)“…Pattern classification is a key approach in Traditional Chinese Medicine (TCM), and it is used to classify the patients for intervention selection accordingly…”
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The Crosstalk of Pathways Involved in Immune Response Maybe the Shared Molecular Basis of Rheumatoid Arthritis and Type 2 Diabetes
Published in PloS one (07-08-2015)“…Rheumatoid arthritis (RA) and Type 2 diabetes (T2D) are both systemic diseases linked with altered immune response, moderate mortality when present together…”
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The shared crosstalk of multiple pathways involved in the inflammation between rheumatoid arthritis and coronary artery disease based on a digital gene expression profile
Published in PloS one (16-12-2014)“…Rheumatoid arthritis (RA) and coronary artery disease (CAD) are both complex inflammatory diseases, and an increased prevalence of CAD and a high rate of…”
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Comparison of toxic reaction of Tripterygium wilfordii multiglycoside in normal and adjuvant arthritic rats
Published in Journal of ethnopharmacology (17-05-2011)“…Multiglycoside of Tripterygium wilfordii F. (GTW) offered a different toxic reactions in normal and adjuvant induced arthritic rats with two dosages (Fig. (A)…”
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10
The effect of curcumin on human bronchial epithelial cells exposed to fine particulate matter: a predictive analysis
Published in Molecules (Basel, Switzerland) (22-10-2012)“…Fine particulate matter (PM₂.₅) has been associated in humans with inflammation, oxidative stress and cancer. Studies had shown that curcumin could potentially…”
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Molecular network and chemical fragment-based characteristics of medicinal herbs with cold and hot properties from Chinese medicine
Published in Journal of ethnopharmacology (30-07-2013)“…Chinese herbal medicines (HMs) is one of the great herbal systems of the world, which play an important role in current health care system in many countries…”
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12
Lipidomic-based investigation into the regulatory effect of Schisandrin B on palmitic acid level in non-alcoholic steatotic livers
Published in Scientific reports (13-03-2015)“…Schisandrin B (SchB) is one of the most abundant bioactive dibenzocyclooctadiene derivatives found in the fruit of Schisandra chinensis . Here, we investigated…”
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13
Maturation of murine bone marrow-derived dendritic cells induced by Radix Glycyrrhizae polysaccharide
Published in Molecules (Basel, Switzerland) (30-05-2012)“…Radix Glycyrrhizae polysaccharide (GP), the most important component of Radix Glycyrrhizae, has been reported to have many immunopharmacological activities…”
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Predicting and verifying outcome of Tripterygium wilfordii Hook F. based therapy in rheumatoid arthritis: from open to double-blinded randomized trial
Published in Scientific reports (15-04-2015)“…Tripterygium wilfordii Hook F. (TwHF) based therapy has been proved as effective in treating rheumatoid arthritis (RA), yet the predictors to its response…”
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15
Molecular mechanism of inhibition of the abnormal proliferation of human umbilical vein endothelial cells by hydroxysafflor-yellow A
Published in Pharmaceutical biology (01-09-2016)“…Context It has been found that hydroxysafflor-yellow A (HSYA) inhibits angiogenesis and the proliferation of abnormal human umbilical vein endothelial cells…”
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Network-Based Gene Expression Biomarkers for Cold and Heat Patterns of Rheumatoid Arthritis in Traditional Chinese Medicine
Published in Evidence-based complementary and alternative medicine (01-01-2012)“…In Traditional Chinese Medicine (TCM), patients with Rheumatoid Arthritis (RA) can be classified into two main patterns: cold-pattern and heat-pattern. This…”
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17
Deciphering the Differential Toxic Responses of Radix aconiti lateralis praeparata in Healthy and Hydrocortisone-Pretreated Rats Based on Serum Metabolic Profiles
Published in Journal of proteome research (04-01-2013)“…Radix aconiti lateralis praeparata (Baifupian) has received great attention because of its excellent therapeutic effects as well as the associated adverse drug…”
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Serum metabolomics reveals betaine and phosphatidylcholine as potential biomarkers for the toxic responses of processed Aconitum carmichaelii Debx
Published in Molecular bioSystems (01-01-2014)“…We recently reported that processed Aconitum carmichaelii Debx (Bai-Fu-Pian in Chinese, BFP) elicits differential toxic responses in rats under various health…”
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Rheumatoid Arthritis with Deficiency Pattern in Traditional Chinese Medicine Shows Correlation with Cold and Hot Patterns in Gene Expression Profiles
Published in Evidence-based complementary and alternative medicine (01-01-2013)“…In our precious study, the correlation between cold and hot patterns in traditional Chinese medicine (TCM) and gene expression profiles in rheumatoid arthritis…”
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Understanding the Molecular Mechanism of Interventions in Treating Rheumatoid Arthritis Patients with Corresponding Traditional Chinese Medicine Patterns Based on Bioinformatics Approach
Published in Evidence-based complementary and alternative medicine (01-01-2012)“…Better effectiveness would be achieved when interventions are used in treating patients with a specific traditional Chinese medicine (TCM) pattern. In this…”
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