Search Results - "Niu, Xiaomin"

FGFR1-ERK1/2-SOX2 axis promotes cell proliferation, epithelial–mesenchymal transition, and metastasis in FGFR1-amplified lung cancer by Wang, Kaixuan, Ji, Wenxiang, Yu, Yongfeng, Li, Ziming, Niu, Xiaomin, Xia, Weiliang, Lu, Shun

“…Epithelial–mesenchymal transition (EMT) is an important process for cancer metastasis, drug resistance, and cancer stem cells. Activation of fibroblast growth…”
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Desuccinylation of pyruvate kinase M2 by SIRT5 contributes to antioxidant response and tumor growth by Xiangyun, Ye, Xiaomin, Niu, Linping, Gu, Yunhua, Xu, Ziming, Li, Yongfeng, Yu, Zhiwei, Chen, Shun, Lu

“…Tumor cells trends to express high level of pyruvate kinase M2 (PKM2). The inhibition of PKM2 activity is needed for antioxidant response by diverting glucose…”
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Systematic comparison of exosomal proteomes from human saliva and serum for the detection of lung cancer by Sun, Yan, Liu, Sha, Qiao, Zhi, Shang, Zhi, Xia, Zhijun, Niu, Xiaomin, Qian, Liqiang, Zhang, Yan, Fan, Liuyin, Cao, Cheng-Xi, Xiao, Hua

“…Circulating tumor exosomes harbor plenty of cancer biological information, which have emerged as promising targets for cancer early detection and diagnosis…”
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RPS6KA1 is a histone acetylation-related oncoprotein in acute myeloid leukemia which is targeted by afzelin by Guo, Xiaojuan, Huang, Guinian, Qiu, Dafa, He, Huiqing, Niu, Xiaomin, Guo, Ziwen, Ye, Yongbin

“…Histone acetylation plays a critical role in the progression of acute myeloid leukemia (AML). This study aimed to explore the prognostic significance and…”
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Comparative Efficacy and Safety of Immunotherapy Alone and in Combination With Chemotherapy for Advanced Non-small Cell Lung Cancer by Wang, Xue, Niu, Xiaomin, An, Na, Sun, Yile, Chen, Zhiwei

“…There is a lack of direct cross-comparison studies in clinical trials between immunotherapy alone and combination treatment, especially in Non-Small Cell Lung…”
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Evaluation of the therapeutic effects of rehabilitation therapy on patients with amyotrophic lateral sclerosis-a meta-analysis by Cheng, Jianghua, Niu, Xiaomin, Li, Hui, Yang, Qiuwei, Du, Ketao

“…To investigate the effect of rehabilitation therapy on the global function, respiratory function, and quality of life in patients with amyotrophic lateral…”
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Harnessing immunotherapy for brain metastases: insights into tumor-brain microenvironment interactions and emerging treatment modalities by Zhou, Dairan, Gong, Zhenyu, Wu, Dejun, Ma, Chao, Hou, Lijun, Niu, Xiaomin, Xu, Tao

“…Brain metastases signify a deleterious milestone in the progression of several advanced cancers, predominantly originating from lung, breast and melanoma…”
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SMO mutation predicts the effect of immune checkpoint inhibitor: From NSCLC to multiple cancers by Ji, Wenxiang, Niu, Xiaomin, Yu, Yongfeng, Li, Ziming, Gu, LinPing, Lu, Shun

“…Background The emergence of immune checkpoint inhibitors (ICIs) is one of the most promising breakthroughs for the treatment of multiple cancer types, but…”
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The polycomb group protein EZH2 inhibits lung cancer cell growth by repressing the transcription factor Nrf2 by Li, Ziming, Xu, Ling, Tang, Naiwang, Xu, Yunhua, Ye, Xiangyun, Shen, Shengping, Niu, Xiaomin, Lu, Shun, Chen, Zhiwei

“…•EZH2 is down-regulated in human NSCLC and low EZH2 predicts poor survival.•EZH2 regulates lung cancer cell growth in vitro and in vivo.•EZH2 inhibits the…”
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Facile preparation of salivary extracellular vesicles for cancer proteomics by Sun, Yan, Xia, Zhijun, Shang, Zhi, Sun, Kaibo, Niu, Xiaomin, Qian, Liqiang, Fan, Liu-Yin, Cao, Cheng-Xi, Xiao, Hua

“…Extracellular vesicles (EVs) are membrane surrounded structures released by cells, which have been increasingly recognized as mediators of intercellular…”
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Homologous recombination deficiency (HRD) can predict the therapeutic outcomes of immuno-neoadjuvant therapy in NSCLC patients by Zhou, Zhen, Ding, Zhengping, Yuan, Jie, Shen, Shengping, Jian, Hong, Tan, Qiang, Yang, Yunhai, Chen, Zhiwei, Luo, Qingquan, Cheng, Xinghua, Yu, Yongfeng, Niu, Xiaomin, Qian, Liqiang, Chen, Xiaoke, Gu, Linping, Liu, Ruijun, Ma, Shenglin, Huang, Jia, Chen, Tianxiang, Li, Ziming, Ji, Wenxiang, Song, Liwei, Shen, Lan, Jiang, Long, Yu, Zicheng, Zhang, Chao, Tai, Zaixian, Wang, Changxi, Chen, Rongrong, Carbone, David P, Xia, Xuefeng, Lu, Shun

“…Neoadjuvant immunotherapy is emerging as novel effective intervention in lung cancer, but study to unearth effective surrogates indicating its therapeutic…”
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Toxic effects of maternal cadmium exposure on the metabolism and transport system of amino acids in the maternal livers by Xu, Peng, Guo, Jing, Jin, Yaling, Lee, Shao Chin, Li, Zhilang, Kong, Lingyu, Liu, Ming, Niu, Xiaomin, Liu, Yun, Bai, Guoqiang, Ren, Lu, Ren, Bei, Fan, Linxiao, Zhao, Meirong, Wang, Lan

“…Fetal growth restriction (FGR) is one of the most common obstetric diseases, and affects approximately 10 % of all pregnancies worldwide. Maternal cadmium (Cd)…”
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Durable Response to the Combination of Atezolizumab With Platinum-Based Chemotherapy in an Untreated Non-Smoking Lung Adenocarcinoma Patient With BRAF V600E Mutation: A Case Report by Niu, Xiaomin, Sun, Yingjia, Planchard, David, Chiu, Luting, Bai, Jian, Ai, Xinghao, Lu, Shun

“…Immune checkpoint inhibitor (ICPi) has become a major treatment in advanced non-small cell lung cancer (NSCLC) and demonstrated a clinical benefit for NSCLC…”
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Polymorphisms of microRNA sequences or binding sites and lung cancer: a meta-analysis and systematic review by Chen, Zhiwei, Xu, Ling, Ye, Xiangyun, Shen, Shengping, Li, Ziming, Niu, Xiaomin, Lu, Shun

“…Functional single nucleotide polymorphisms (SNPs) of microRNA (miRNA) sequences or binding sites (miRNA-SNPs) are associated with lung cancer risk and…”
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An open, observational, three-arm clinical study of 2–3 cycles of treatment as neoadjuvant therapy in operable locally advanced non-small cell lung cancer: An interim analysis by Gu, Linping, Wang, Xue, Sun, Yile, Xu, Yunhua, Niu, Xiaomin, Zhao, Ruiying, Yao, Yaxian, Jian, Hong, Han, Yuchen, Wei, Jinwang, Chen, Zhiwei, Lu, Shun

“…Background An open, observational, three-arm clinical study aimed at investigating the efficacy of different neoadjuvant therapies (neoadjuvant immunotherapy…”
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Current status and continuing medical education need for general practitioners in Tibet, China: a cross-sectional study by Yang, Sen, Zhao, Huaxin, Zhang, Hanzhi, Wang, Junpeng, Jin, Hua, Stirling, Kyle, Ge, Xuhua, Ma, Le, Pu, Zhen, Niu, Xiaomin, Yu, Dehua

“…The Tibetan area is one of China's minority regions with a shortage of general practice personnel, which requires further training and staffing. This research…”
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Genome-wide DNA Methylation Analysis Reveals GABBR2 as a Novel Epigenetic Target for EGFR 19 Deletion Lung Adenocarcinoma with Induction Erlotinib Treatment by Niu, Xiaomin, Liu, Fatao, Zhou, Yi, Zhou, Zhen, Zhou, Daizhan, Wang, Ting, Li, Ziming, Ye, Xiangyun, Yu, Yongfeng, Weng, Xiaoling, Zhang, Hong, Ye, Junyi, Liao, Meilin, Liu, Yun, Chen, Zhiwei, Lu, Shun

“…The past decade has witnessed the rapid development of personalized targeted therapies in lung cancer. It is still unclear whether epigenetic changes are…”
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Docetaxel prodrug and hematoporphyrin co-assembled nanoparticles for anti-tumor combination of chemotherapy and photodynamic therapy by Ren, Guolian, Li, Yujie, Ping, Canqi, Duan, Danyu, Li, Ning, Tang, Jiaqi, Wang, Rongrong, Guo, Wenju, Niu, Xiaomin, Ji, Qiuyue, Zhang, Guoshun, Wang, Ruili, Zhang, Shuqiu

“…To realize the synergistic anti-tumor effect of chemotherapy and photodynamic therapy, the mono sulfide-modified docetaxel (DTX) prodrugs (DSD) provided by our…”
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Complex renal cysts combined with hemorrhage during crizotinib treatment for ALK-rearranged lung adenocarcinoma by Yang, Ling, Gu, Jianing, Niu, Xiaomin

“…The oral small-molecule tyrosine kinase inhibitor (TKI), crizotinib has been approved as a first-generation anaplastic lymphoma kinase (ALK) inhibitor in…”
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Comparison of clinical outcomes and risk factors for COVID-19 infection in cancer patients without anticancer treatment and noncancer patients by Yang, Sen, Zhao, Huaxin, Cui, Ran, Ma, Le, Ge, Xuhua, Fu, Qiangqiang, Yu, Dehua, Niu, Xiaomin

“…Previous studies have shown that cancer patients have higher rates of coronavirus disease 2019 (COVID-19) infection and mortality than noncancer patients…”
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