Search Results - "Niu, Junqi"
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Incidence and Etiology of Drug-Induced Liver Injury in Mainland China
Published in Gastroenterology (New York, N.Y. 1943) (01-06-2019)“…We performed a nationwide, retrospective study to determine the incidence and causes of drug-induced liver injury (DILI) in mainland China. We collected data…”
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2
Platelets mediate inflammatory monocyte activation by SARS-CoV-2 spike protein
Published in The Journal of clinical investigation (15-02-2022)“…Infection with SARS-CoV-2, the causative agent of COVID-19, causes mild to moderate disease in most patients but carries a risk of morbidity and mortality…”
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3
The assessment of mesenchymal stem cells therapy in acute on chronic liver failure and chronic liver disease: a systematic review and meta-analysis of randomized controlled clinical trials
Published in Stem cell research & therapy (16-05-2022)“…Mesenchymal stem cells (MSCs) therapy is showing potential therapeutic effects on liver function improvement in patients with chronic liver disease; however,…”
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4
ALDH2 deficiency promotes alcohol-associated liver cancer by activating oncogenic pathways via oxidized DNA-enriched extracellular vesicles
Published in Journal of hepatology (01-11-2019)“…[Display omitted] •ALDH2 deficiency is associated with an increased risk of HCC from cirrhosis in those who drink alcohol.•Chronic CCl4+EtOH treatment induces…”
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5
Serum metabolome and targeted bile acid profiling reveals potential novel biomarkers for drug-induced liver injury
Published in Medicine (Baltimore) (01-08-2019)“…This study aims to determine the non-invasive, reliable and sensitive biochemical parameters for the diagnosis of drug-induced liver injury (DILI).Ultra-high…”
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6
Identification of Immune Microenvironment Changes and the Expression of Immune-Related Genes in Liver Cirrhosis
Published in Frontiers in immunology (12-07-2022)“…Liver inflammation and the immune response have been recognized as critical contributors to cirrhosis pathogenesis. Immunity-related genes (IRGs) play an…”
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7
Exosomes target HBV-host interactions to remodel the hepatic immune microenvironment
Published in Journal of nanobiotechnology (05-06-2024)“…Chronic hepatitis B poses a significant global burden, modulating immune cells, leading to chronic inflammation and long-term damage. Due to its hepatotropism,…”
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8
Liver sinusoidal endothelial cells are implicated in multiple fibrotic mechanisms
Published in Molecular biology reports (01-03-2021)“…Chronic liver diseases are attributed to liver injury. Development of fibrosis from chronic liver diseases is a dynamic process that involves multiple…”
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9
Hepatitis B virus infection and immunopathogenesis in a humanized mouse model: induction of human-specific liver fibrosis and M2-like macrophages
Published in PLoS pathogens (01-03-2014)“…The mechanisms of chronic HBV infection and immunopathogenesis are poorly understood due to a lack of a robust small animal model. Here we report the…”
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No evidence for a causal link between Helicobacter pylori infection and nonalcoholic fatty liver disease: A bidirectional Mendelian randomization study
Published in Frontiers in microbiology (03-11-2022)“…Although clinical studies have shown the possible relationship between ( ) infection and the development of nonalcoholic fatty liver disease (NAFLD), their…”
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MDA5 plays a critical role in interferon response during hepatitis C virus infection
Published in Journal of hepatology (01-04-2015)“…Graphical abstract…”
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12
ELISA genotyping of hepatitis B virus in China with antibodies specific for genotypes B and C
Published in Scientific reports (12-10-2024)“…Hepatitis B virus (HBV) causes hepatitis B (HB) and distinct HBV genotypes can lead to different prognoses. However, HBV genotyping is rarely done in clinics,…”
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13
MicroRNA‐206 prevents the pathogenesis of hepatocellular carcinoma by modulating expression of met proto‐oncogene and cyclin‐dependent kinase 6 in mice
Published in Hepatology (Baltimore, Md.) (01-12-2017)“…Hepatocellular carcinoma (HCC) is one of the most lethal cancers worldwide, and therapeutic agents for this malignancy are lacking. MicroRNAs play critical…”
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14
Human umbilical cord mesenchymal stromal cell-derived exosomes protect against MCD-induced NASH in a mouse model
Published in Stem cell research & therapy (12-11-2022)“…Abstract Background and aims Human umbilical cord mesenchymal stem cells (hUC-MSCs) are increasingly being studied in clinical trials of end-stage liver…”
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15
Surgical treatment of acromioclavicular joint dislocation of Rockwood III/IV: a retrospective study on clavicular hook plate versus arthroscopic TightRope loop titanium button
Published in BMC musculoskeletal disorders (26-02-2024)“…To compare the clinical efficacy of arthroscopic TightRope loop titanium button and clavicular hook plate in the treatment of acromioclavicular joint (ACJ)…”
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The association between Fc gamma RIIb expression levels and chronic hepatitis B virus infection progression
Published in BMC infectious diseases (08-12-2021)“…Fc gamma receptor IIb (FcγRIIb) is an important inhibitory receptor that plays vital roles in regulating various immune response processes and the pathogenesis…”
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The HIF1α-PDGFD-PDGFRα axis controls glioblastoma growth at normoxia/mild-hypoxia and confers sensitivity to targeted therapy by echinomycin
Published in Journal of experimental & clinical cancer research (01-09-2021)“…Glioblastoma multiforme (GBM), a lethal brain tumor, remains the most daunting challenge in cancer therapy. Overexpression and constitutive activation of PDGFs…”
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Peroxisome Proliferator-Activated Receptors Regulate Hepatic Immunity and Assist in the Treatment of Primary Biliary Cholangitis
Published in Frontiers in immunology (08-07-2022)“…Fibrates, which are agonists of peroxisome proliferator-activated receptor alpha, have received increasing attention in the treatment of primary biliary…”
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Association of serum level of growth differentiation factor 15 with liver cirrhosis and hepatocellular carcinoma
Published in PloS one (21-05-2015)“…Hepatocellular carcinoma (HCC) and liver cirrhosis are associated with high mortality worldwide. Currently, alpha-fetoprotein (AFP) is used as a standard serum…”
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PHD-finger family genes in wheat ( Triticum aestivum L.): Evolutionary conservatism, functional diversification, and active expression in abiotic stress
Published in Frontiers in plant science (12-12-2022)“…Plant homeodomain (PHD) transcription factors (TFs) are a class of proteins with conserved Cys4-His-Cys3 domains that play important roles in plant growth and…”
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