Search Results - "Nissley, D. V"
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Sensitive Drug-Resistance Assays Reveal Long-Term Persistence of HIV-1 Variants with the K103N Nevirapine (NVP) Resistance Mutation in Some Women and Infants after the Administration of Single-Dose NVP: HIVNET 012
Published in The Journal of infectious diseases (01-07-2005)“…BackgroundThe HIV Network for Prevention Trials (HIVNET) 012 trial showed that NVP resistance (NVPR) emerged in some women and children after the…”
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HIV reverse transcription in yeast
Published in Nature (London) (07-03-1996)“…The study of human immunodeficiency virus (HIV) reverse transcriptase/ribonuclease H (RT/RH) and other medically important reverse transcriptases would be…”
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Mutations in the inverted repeats of Tn3 affect binding of transposase and transposition immunity
Published in Journal of molecular biology (20-03-1991)“…In order to better understand the interaction between the inverted repeats (IRs) of the transposon Tn3 and Tn3 transposase, we have looked at the effects of…”
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Mutational analysis of the inverted repeats of Tn3
Published in Journal of molecular biology (20-06-1990)“…The transposase protein and the terminal inverted repeat sequences of the prokaryotic transposon Tn3 are essential for transposition. In order to determine the…”
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Hybrid Ty1/HIV-1 Elements Used to Detect Inhibitors and Monitor the Activity of HIV-1 Reverse Transcriptase
Published in Proceedings of the National Academy of Sciences - PNAS (10-11-1998)“…We previously demonstrated that hybrid retotransposons composed of the yeast Ty1 element and the reverse transcriptase (RT) of HIV-1 are active in the yeast…”
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APOBEC3G hypermutates genomic DNA and inhibits Ty1 retrotransposition in yeast
Published in Proceedings of the National Academy of Sciences - PNAS (12-07-2005)“…Human cells harbor a variety of factors that function to block the proliferation of foreign nucleic acid. The APOBEC3G enzyme inhibits the replication of…”
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Sensitive Phenotypic Detection of Minor Drug-Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase Variants
Published in Journal of Clinical Microbiology (01-11-2005)“…Detection of drug-resistant variants is important for the clinical management of human immunodeficiency virus type 1 (HIV-1) infection and for studies on the…”
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