Search Results - "Nissinen, Markku J"

Parenteral Plant Sterols and Intestinal Failure–associated Liver Disease in Neonates by Kurvinen, Annika, Nissinen, Markku J., Andersson, Sture, Korhonen, Päivi, Ruuska, Tarja, Taimisto, Mari, Kalliomäki, Marko, Lehtonen, Liisa, Sankilampi, Ulla, Arikoski, Pekka, Saarela, Timo, Miettinen, Tatu A., Gylling, Helena, Pakarinen, Mikko P.

“…ABSTRACT Objectives: We prospectively evaluated incidence of prolonged (>28 days) parenteral nutrition (PN), associated complications, and significance of…”
Get full text

Responses of surrogate markers of cholesterol absorption and synthesis to changes in cholesterol metabolism during various amounts of fat and cholesterol feeding among healthy men by Nissinen, Markku J., Gylling, Helena, Miettinen, Tatu A.

“…Serum ratios to cholesterol of lathosterol, and of cholestanol, campesterol and sitosterol measure respective relative cholesterol synthesis and absorption,…”
Get full text

Coexistence of metabolic-associated fatty liver disease and autoimmune or toxic liver disease by Danielsson, Oscar, Vesterinen, Tiina, Arola, Johanna, Åberg, Fredrik, Nissinen, Markku J

“…Fatty liver disease (FLD) affects approximately 25% of global adult population. Metabolic-associated fatty liver disease (MAFLD) is a term used to emphasize…”
Get full text

Waist and hip circumference are independently associated with the risk of liver disease in population‐based studies by Danielsson, Oscar, Nissinen, Markku J., Jula, Antti, Salomaa, Veikko, Männistö, Satu, Lundqvist, Annamari, Perola, Markus, Åberg, Fredrik

“…Background & Aims While several anthropometric measures predict liver disease, the waist‐hip ratio (WHR) has shown superiority in previous studies. We analysed…”
Get full text

Serum non-cholesterol sterols and cholesterol metabolism in childhood and adolescence by Gylling, Helena, Korhonen, Matilda, Mutanen, Annika, Nissinen, Markku J., Pakarinen, Mikko, Simonen, Piia

“…The profile of cholesterol metabolism, i.e., high absorption vs. high synthesis, may have a role in the development of atherosclerosis, the early lesions of…”
Get full text

Serum plant sterols, cholestanol, and cholesterol precursors associate with histological liver injury in pediatric onset intestinal failure by Mutanen, Annika, Nissinen, Markku J, Lohi, Jouko, Heikkilä, Päivi, Gylling, Helena, Pakarinen, Mikko P

“…Background: Increased serum concentrations of plant sterols, including stigmasterol, during parenteral nutrition (PN) have been linked with serum biochemical…”
Get full text

Validity of fatty liver disease indices in the presence of alcohol consumption by Danielsson, Oscar, Nano, Jana, Pahkala, Katja, Rospleszcz, Susanne, Lehtimäki, Terho, Schlett, Christopher L., Kähönen, Mika, Bamberg, Fabian, Raitakari, Olli, Peters, Annette, Nissinen, Markku J., Åberg, Fredrik O.

“…Non-alcoholic fatty liver disease (NAFLD) and alcohol-related liver disease frequently coexist. While several blood-based indices exist for the detection of…”
Get full text

Serum noncholesterol sterols in Alzheimer's disease: the Helsinki Businessmen Study by Sittiwet, Chaiyasit, Simonen, Piia, Nissinen, Markku J., Gylling, Helena, Strandberg, Timo E.

“…Cerebral cholesterol metabolism is perturbed in late-onset Alzheimer's disease (AD), but whether also the extracerebral cholesterol metabolism is perturbed is…”
Get full text

The effect of a very high daily plant stanol ester intake on serum lipids, carotenoids, and fat-soluble vitamins by Gylling, Helena, Hallikainen, Maarit, Nissinen, Markku J, Miettinen, Tatu A

“…Summary Background & aims Intake of 2–3 g/d of plant stanols as esters lowers LDL cholesterol level, but there is no information about the efficacy and safety…”
Get full text

Genetic polymorphism of sterol transporters in children with future gallstones by Nissinen, Markku J., Pitkänen, Niina, Simonen, Piia, Gylling, Helena, Viikari, Jorma, Raitakari, Olli, Lehtimäki, Terho, Juonala, Markus, Pakarinen, Mikko P.

“…Gallstone disease is related to hypersecretion of cholesterol in bile, and low serum phytosterol levels. We examined how genetic polymorphisms of sterol…”
Get full text

Relation of cholesterol metabolism to pediatric gallstone disease: a retrospective controlled study by Koivusalo, Antti, Pakarinen, Mikko, Gylling, Helena, Nissinen, Markku J

“…Cholesterol metabolism may be involved in pediatric gallstone disease. We aimed to reveal cholesterol metabolites and phytosterols and their relation to stone…”
Get full text

Low Childhood Cholesterol Absorption Predisposes to Gallstone Disease: The Cardiovascular Risk in Young Finns Study by Nissinen, Markku J, Simonen, Piia, Gylling, Helena, Viikari, Jorma, Hutri-Kähönen, Nina, Jokinen, Eero, Tossavainen, Päivi, Laitinen, Tomi, Raitakari, Olli, Juonala, Markus, Pakarinen, Mikko P

“…OBJECTIVES:Unraveling pathogenesis of gallstones could help to diminish its enormous disease burden. We hypothesized that certain properties of childhood…”
Get full text

Effects of Long‐term Parenteral Nutrition on Serum Lipids, Plant Sterols, Cholesterol Metabolism, and Liver Histology in Pediatric Intestinal Failure by Kurvinen, Annika, Nissinen, Markku J., Gylling, Helena, Miettinen, Tatu A., Lampela, Hanna, Koivusalo, Antti I., Rintala, Risto J., Pakarinen, Mikko P.

“…ABSTRACT Background and Objective: Plant sterols (PS) in parenteral nutrition (PN) may contribute to intestinal failure–associated liver disease. We…”
Get full text

Determining the mechanisms of dietary turnip rapeseed oil on cholesterol metabolism in men with metabolic syndrome by Saarinen, Harri Juhani, Sittiwet, Chaiyasit, Simonen, Piia, Nissinen, Markku J, Stenman, Ulf-Håkan, Gylling, Helena, Palomäki, Ari

“…We have earlier reported the reduction of total cholesterol, low-density lipoprotein (LDL) cholesterol and oxidized LDL caused by short-term modification of…”
Get full text

The effects of plant stanol ester consumption on arterial stiffness and endothelial function in adults: a randomised controlled clinical trial by Gylling, Helena, Halonen, Janne, Lindholm, Harri, Konttinen, Jussi, Simonen, Piia, Nissinen, Markku J, Savolainen, Aslak, Talvi, Airi, Hallikainen, Maarit

“…The hypocholesterolemic effect of plant stanol ester consumption has been studied extensively, but its effect on cardiovascular health has been less frequently…”
Get full text

Cholesterol lowering efficacy of plant stanol ester in a new type of product matrix, a chewable dietary supplement by Laitinen, Kirsi, Gylling, Helena, Kaipiainen, Leena, Nissinen, Markku J., Simonen, Piia

“…•A new type of chewable plant stanol (2g/d) ester food supplement was developed.•LDL cholesterol was reduced by 7.6% vs controls (P=0.001).•No side effects…”
Get full text

Ileal pouch-anal anastomosis, conventional ileostomy and ileorectal anastomosis modify cholesterol metabolism by NISSINEN, Markku J, GYLLING, Helena, JÄRVINEN, Heikki J, MIETTINEN, Tatu A

“…Proctocolectomy modifies the enterohepatic circulation and activity of bacterial enzymes depending on the structure of the stoma and function of the terminal…”
Get full text

Very high plant stanol intake and serum plant stanols and non-cholesterol sterols by Gylling, Helena, Hallikainen, Maarit, Nissinen, Markku J, Simonen, Piia, Miettinen, Tatu A

“…Background Today, consumers meet abundant supply of functional foods with plant stanol increments for serum cholesterol lowering purposes. However, efficacy…”
Get full text

Diet and cardiovascular health in asymptomatic normo- and mildly-to-moderately hypercholesterolemic participants - baseline data from the BLOOD FLOW intervention study by Hallikainen, Maarit, Halonen, Janne, Konttinen, Jussi, Lindholm, Harri, Simonen, Piia, Nissinen, Markku J, Gylling, Helena

“…For decades in Finland, intensive population strategies and preventive activities have been used to lower the risk of atherosclerotic coronary heart disease…”
Get full text

Serum sterols in patients with primary biliary cirrhosis and acute liver failure before and after liver transplantation by Nikkilä, Katriina, Nissinen, Markku J, Gylling, Helena, Isoniemi, Helena, Miettinen, Tatu A

“…Background/Aims Liver diseases modify sterol metabolism. Liver transplantation (LTX) provides a model to evaluate the impact of disease-affected liver on…”
Get full text