Search Results - "Nissen, Mogens H"

Inflammatory cytokines protect retinal pigment epithelial cells from oxidative stress-induced death by Juel, Helene B, Faber, Carsten, Svendsen, Signe G, Vallejo, Abbe N, Nissen, Mogens H

“…To investigate the effects of inflammatory factors and oxidative stress on cell survival of the human retinal pigment epithelial (RPE) cell line, ARPE-19…”
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Early changes in gene expression induced by blue light irradiation of A2E‐laden retinal pigment epithelial cells by van der Burght, Barbro W., Hansen, Morten, Olsen, Jørgen, Zhou, Jilin, Wu, Yalin, Nissen, Mogens H., Sparrow, Janet R.

“… Purpose:  Accumulation of bisretinoids as lipofuscin in retinal pigment epithelial (RPE) cells is implicated in the pathogenesis of some blinding diseases…”
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Unfolding, Aggregation, and Seeded Amyloid Formation of Lysine-58-Cleaved β2-Microglobulin by Heegaard, Niels H. H, Jørgensen, Thomas J. D, Rozlosnik, Noémi, Corlin, Dorthe B, Pedersen, Jesper S, Tempesta, Anna G, Roepstorff, Peter, Bauer, Rogert, Nissen, Mogens H

“…β2-Microglobulin (β2m) is the amyloidogenic protein in dialysis-related amyloidosis, but the mechanisms underlying β2m fibrillogenesis in vivo are largely…”
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The effect of a therapeutic dendritic cell-based cancer vaccination depends on the blockage of CTLA-4 signaling by Met, Özcan, Wang, Mingjun, Pedersen, Anders E., Nissen, Mogens H., Buus, Søren, Claesson, Mogens H.

“…Dendritic cells (DCs) were pulsed with the H-2K b binding OVA 257-264-peptide (SIINFEKL), and used as one single-injection vaccine in combination with…”
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Quantification of cleaved β2-microglobulin in serum from patients undergoing chronic hemodialysis by CORLIN, Dorthe B, SEN, Jette W, LADEFOGED, Søren, BJERREGAARD LUND, Grethe, NISSEN, Mogens H, HEEGAARD, Niels H. H

“…Abstract Background: Patients on chronic hemodialysis are prone to develop amyloid deposits of misfolded β2-microglobulin (β2M) in osteoarticular tissues. β2M…”
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Induction of Chemokine Secretion and Monocyte Migration by Human Choroidal Melanocytes in Response to Proinflammatory Cytokines by Jehs, Tina, Faber, Carsten, Udsen, Maja S, Jager, Martine J, Clark, Simon J, Nissen, Mogens H

“…To determine to which extent inflammatory cytokines affect chemokine secretion by primary human choroidal melanocytes (HCMs), their capacity to attract…”
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Patients with a fast progression profile in geographic atrophy have increased CD200 expression on circulating monocytes by Krogh Nielsen, Marie, Subhi, Yousif, Molbech, Christopher R, Falk, Mads K, Singh, Amardeep, Nissen, Mogens H, Sørensen, Torben L

“…Importance Geographic atrophy (GA) is a progressing atrophy of the neuroretina with no treatment option. Background Age‐related malfunction of retinal…”
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Chemokine expression in retinal pigment epithelial ARPE-19 cells in response to coculture with activated T cells by Juel, Helene B, Faber, Carsten, Udsen, Maja S, Folkersen, Lasse, Nissen, Mogens H

“…To investigate the effects of T-cell-derived cytokines on gene and protein expression of chemokines in a human RPE cell line (ARPE-19). We used an in vitro…”
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Subretinal Posterior Pole Injury Induces Selective Proliferation of RPE Cells in the Periphery in In Vivo Studies in Pigs by Kiilgaard, Jens F, Prause, Jan U, Prause, Michala, Scherfig, Erik, Nissen, Mogens H, la Cour, Morten

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Congophilicity (Congo red affinity) of different β2-microglobulin conformations characterized by dye affinity capillary electrophoresis by HEEGAARD, Niels H. H, SEN, Jette W, NISSEN, Mogens H

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Altered Expression of CD46 and CD59 on Leukocytes in Neovascular Age-Related Macular Degeneration by Singh, Amardeep, Faber, Carsten, Falk, Mads, Nissen, Mogens H, Hviid, Thomas V.F, Sørensen, Torben L

“…Purpose To investigate the expression of the complement regulatory proteins CD46, CD55, and CD59 on peripheral leukocytes in neovascular age-related macular…”
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Inflammation-induced chemokine expression in uveal melanoma cell lines stimulates monocyte chemotaxis by Jehs, Tina, Faber, Carsten, Juel, Helene B, Bronkhorst, Inge H G, Jager, Martine J, Nissen, Mogens H

“…Uveal melanoma (UM) is the most common primary intraocular tumor in adults and the presence of infiltrating leucocytes is associated with a poor prognosis…”
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Astrocytoma cells upregulate expression of pro-inflammatory cytokines after co-culture with activated peripheral blood mononuclear cells by JEHS, TINA, FABER, CARSTEN, JUEL, HELENE B., NISSEN, MOGENS H.

“…Jehs T, Faber C, Juel HB, Nissen MH. Astrocytoma cells upregulate expression of pro‐inflammatory cytokines after co‐culture with activated peripheral blood…”
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Deficient SOCS3 and SHP-1 Expression in Psoriatic T Cells by Eriksen, Karsten W., Woetmann, Anders, Skov, Lone, Krejsgaard, Thorbjørn, Bovin, Lone F., Hansen, Mikkel L., Grønbæk, Kirsten, Billestrup, Nils, Nissen, Mogens H., Geisler, Carsten, Wasik, Mariusz A., Ødum, Niels

“…IFN-α and skin-infiltrating activated T lymphocytes have important roles in the pathogenesis of psoriasis. T cells from psoriatic patients display an increased…”
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Retinal pigment epithelial cells upregulate expression of complement factors after co-culture with activated T cells by Juel, Helene B., Kaestel, Charlotte, Folkersen, Lasse, Faber, Carsten, Heegaard, Niels H.H., Borup, Rehannah, Nissen, Mogens H.

“…In this study we examined the effect of T cell-derived cytokines on retinal pigment epithelial (RPE) cells with respect to expression of complement components…”
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Subretinal posterior pole injury induces selective proliferation of RPE cells in the periphery in in vivo studies in pigs by Kiilgaard, Jens F, Prause, Jan U, Prause, Michala, Scherfig, Erik, Nissen, Mogens H, la Cour, Morten

“…To study topographical differences in porcine retinal pigment epithelial (RPE) cell proliferation (1) in vivo, after experimental central surgical subretinal…”
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Vitreous humor and albumin augment the proliferation of cultured retinal precursor cells by Yang, Jing, Klassen, Henry, Pries, Mette, Wang, Wei, Nissen, Mogens H.

“…Intravitreal injection is an important delivery route for studies involving the transplantation of various types of precursor cells to the retina; however, the…”
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Aqueous Humor Enhances the Proliferation of Rat Retinal Precursor Cells in Culture, and This Effect Is Partially Reproduced by Ascorbic Acid by Yang, Jing, Klassen, Henry, Pries, Mette, Wang, Wei, Nissen, Mogens H.

“…Aqueous humor has been shown to influence the proliferation of various ocular cell types, but the effect on immature retinal cells is not known. Here, the…”
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Glycosaminoglycans enhance the fibrillation propensity of the β2-microglobulin cleavage variant--ΔK58-β2m by Corlin, Dorthe B, Johnsen, Christina K, Nissen, Mogens H, Heegaard, Niels H H

“…Dialysis related amyloidosis (DRA) is a serious complication to long-term hemodialysis treatment which causes clinical symptoms such as carpal tunnel syndrome…”
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Orthotopic porcine corneal xenotransplantation using a human graft by Faber, Carsten, Wang, Mingjun, Scherfig, Erik, Sørensen, Knud Erik, Prause, Jan Ulrik, Ehlers, Niels, Nissen, Mogens H.

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