Search Results - "Nishizawa, Satoru"

Biological roles of glial fibrillary acidic protein as a biomarker in cartilage regenerative medicine by Kanazawa, Sanshiro, Nishizawa, Satoru, Takato, Tsuyoshi, Hoshi, Kazuto

“…Glial fibrillary acidic protein (GFAP) is an intermediate filament that is expressed in specifically expressed auricular chondrocytes, which are good cell…”
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Cancer with low cathepsin D levels is susceptible to vacuolar (H+)‐ATPase inhibition by Kitazawa, Satoshi, Nishizawa, Satoru, Nakagawa, Hideyuki, Funata, Masaaki, Nishimura, Kazuho, Soga, Tomoyoshi, Hara, Takahito

“…Vacuolar (H+)‐ATPases (V‐ATPases) have important roles in the supply of nutrients to tumors by mediating autophagy and the endocytic uptake of extracellular…”
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The optimization of porous polymeric scaffolds for chondrocyte/atelocollagen based tissue-engineered cartilage by Tanaka, Yoko, Yamaoka, Hisayo, Nishizawa, Satoru, Nagata, Satoru, Ogasawara, Toru, Asawa, Yukiyo, Fujihara, Yuko, Takato, Tsuyoshi, Hoshi, Kazuto

“…Abstract To broaden the clinical application of cartilage regenerative medicine, we should develop an implant-type tissue-engineered cartilage with firmness…”
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Early stage foreign body reaction against biodegradable polymer scaffolds affects tissue regeneration during the autologous transplantation of tissue-engineered cartilage in the canine model by Asawa, Yukiyo, Sakamoto, Tomoaki, Komura, Makoto, Watanabe, Makoto, Nishizawa, Satoru, Takazawa, Yutaka, Takato, Tsuyoshi, Hoshi, Kazuto

“…To overcome the weak points of the present cartilage regenerative medicine, we applied a porous scaffold for the production of tissue-engineered cartilage with…”
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Application of induced pluripotent stem cells for cartilage regeneration in CLAWN miniature pig osteochondral replacement model by Uto, Sakura, Nishizawa, Satoru, Hikita, Atsuhiko, Takato, Tsuyoshi, Hoshi, Kazuto

“…Pluripotent stem cells have an advantage that they can proliferate without reduction of the quality, while they have risk of tumorigenesis. It is desirable…”
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Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitor by Iwai, Kenichi, Nambu, Tadahiro, Dairiki, Ryo, Ohori, Momoko, Yu, Jie, Burke, Kristine, Gotou, Masamitsu, Yamamoto, Yukiko, Ebara, Shunsuke, Shibata, Sachio, Hibino, Ryosuke, Nishizawa, Satoru, Miyazaki, Tohru, Homma, Misaki, Oguro, Yuya, Imada, Takashi, Cho, Nobuo, Uchiyama, Noriko, Kogame, Akifumi, Takeuchi, Toshiyuki, Kurasawa, Osamu, Yamanaka, Kazunori, Niu, Huifeng, Ohashi, Akihiro

“…Replication stress (RS) is a cancer hallmark; chemotherapeutic drugs targeting RS are widely used as treatments for various cancers. To develop next-generation…”
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Intratumor Heterogeneity in Primary Kidney Cancer Revealed by Metabolic Profiling of Multiple Spatially Separated Samples within Tumors by Okegawa, Takatsugu, Morimoto, Megumi, Nishizawa, Satoru, Kitazawa, Satoshi, Honda, Kohei, Araki, Hideo, Tamura, Toshiya, Ando, Ayumi, Satomi, Yoshinori, Nutahara, Kikuo, Hara, Takahito

“…Metabolic alteration constitutes a hallmark of cancer. Glycolysis and antioxidant pathways in kidney cancer are elevated, with frequent mutation of the VHL…”
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Cartilage tissue engineering using human auricular chondrocytes embedded in different hydrogel materials by Yamaoka, Hisayo, Asato, Hirotaka, Ogasawara, Toru, Nishizawa, Satoru, Takahashi, Tsuguharu, Nakatsuka, Takashi, Koshima, Isao, Nakamura, Kozo, Kawaguchi, Hiroshi, Chung, Ung-il, Takato, Tsuyoshi, Hoshi, Kazuto

“…To seek a suitable scaffold for cartilage tissue engineering, we compared various hydrogel materials originating from animals, plants, or synthetic peptides…”
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Assessing the association between care quality and household chore rules in residential care institutions in Japan by Mizuki, Rie, Kyuzen, Mamiko, Nishizawa, Satoru, Mori, Shigeyuki

“…The performance of household chores by children in Japanese residential care institutions has been widely accepted as a practice that fosters children’s…”
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Bone and cartilage repair by transplantation of induced pluripotent stem cells in murine joint defect model by UTO, Sakura, NISHIZAWA, Satoru, TAKASAWA, Yutaka, ASAWA, Yukiyo, FUJIHARA, Yuko, TAKATO, Tsuyoshi, HOSHI, Kazuto

“…The establishment of cartilage regenerative medicine has been an important issue in the clinical field, because cartilage has the poor ability of self-repair…”
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RECONSIDERING RECENT DEVELOPMENTS IN JAPANESE RESIDENTIAL CARE AND THE ROAD TO FICE JAPAN by Mori, Shigeyuki, Nishizawa, Satoru, Kimura, Arimi

“…In order to foster interactive discussions with other countries, this paper offers an overview of residential care for children in Japan and its ongoing…”
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Optimal conditions of collagenase treatment for isolation of articular chondrocytes from aged human tissues by Yonenaga, Kazumichi, Nishizawa, Satoru, Nakagawa, Takumi, Fujihara, Yuko, Asawa, Yukiyo, Hikita, Atsuhiko, Takato, Tsuyoshi, Hoshi, Kazuto

“…There are various types of cartilage, including the auricular and articular cartilages. These cartilages have different functions, and their matrix volume and…”
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Three-dimensional changes of noses after transplantation of implant-type tissue-engineered cartilage for secondary correction of cleft lip–nose patients by Hoshi, Kazuto, Fujihara, Yuko, Saijo, Hideto, Kurabayashi, Kumiko, Suenaga, Hideyuki, Asawa, Yukiyo, Nishizawa, Satoru, Kanazawa, Sanshiro, Uto, Sakura, Inaki, Ryoko, Matsuyama, Mariko, Sakamoto, Tomoaki, Watanabe, Makoto, Sugiyama, Madoka, Yonenaga, Kazumichi, Hikita, Atsuhiko, Takato, Tsuyoshi

“…We have developed an implant-type tissue-engineered cartilage using a poly-l-lactide scaffold. In a clinical study, it was inserted into subcutaneous areas of…”
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Glial Fibrillary Acidic Protein as Biomarker Indicates Purity and Property of Auricular Chondrocytes by Nishizawa, Satoru, Kanazawa, Sanshiro, Fujihara, Yuko, Asawa, Yukiyo, Nagata, Satoru, Harai, Motohiro, Hikita, Atsuhiko, Takato, Tsuyoshi, Hoshi, Kazuto

“…Instead of the silicone implants previously used for repair and reconstruction of the auricle and nose lost due to accidents and disease, a new treatment…”
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Impairment of the transition from proliferative stage to prehypertrophic stage in chondrogenic differentiation of human induced pluripotent stem cells harboring the causative mutation of achondroplasia in fibroblast growth factor receptor 3 by Horie, Naohiro, Hikita, Atsuhiko, Nishizawa, Satoru, Uto, Sakura, Takato, Tsuyoshi, Hoshi, Kazuto

“…Achondroplasia (ACH) is a congenital disease which causes dwarfism and many symptoms resulting from skeletal dysplasia. Because present therapeutic strategies…”
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Evaluation of the implant type tissue-engineered cartilage by scanning acoustic microscopy by Tanaka, Yoko, Saijo, Yoshifumi, Fujihara, Yuko, Yamaoka, Hisayo, Nishizawa, Satoru, Nagata, Satoru, Ogasawara, Toru, Asawa, Yukiyo, Takato, Tsuyoshi, Hoshi, Kazuto

“…The tissue-engineered cartilages after implantation were nonuniform tissues which were mingling with biodegradable polymers, regeneration cartilage and others…”
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Aptitude of auricular and nasoseptal chondrocytes cultured under a monolayer or three-dimensional condition for cartilage tissue engineering by Asawa, Yukiyo, Ogasawara, Toru, Takahashi, Tsuguharu, Yamaoka, Hisayo, Nishizawa, Satoru, Matsudaira, Ko, Mori, Yoshiyuki, Takato, Tsuyoshi, Hoshi, Kazuto

“…To elucidate the characterizations of chondrocytes originating from auricular cartilage (donors: 10-15 years) and nasoseptal one (20-23 years), we evaluated…”
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Preclinical and clinical research on bone and cartilage regenerative medicine in oral and maxillofacial region by Takato, Tsuyoshi, Mori, Yoshiyuki, Fujihara, Yuko, Asawa, Yukiyo, Nishizawa, Satoru, Kanazawa, Sanshiro, Ogasawara, Toru, Saijo, Hideto, Abe, Takahiro, Abe, Masanobu, Suenaga, Hideyuki, Kanno, Yuki, Sugiyama, Madoka, Hoshi, Kazuto

“…Recently, there have been remarkable advances in regenerative medicine, and almost all disorders of the oral and maxillofacial region could be research targets…”
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BMP-2 embedded atelocollagen scaffold for tissue-engineered cartilage cultured in the medium containing insulin and triiodothyronine--a new protocol for three-dimensional in vitro culture of human chondrocytes by Ko, Edward Chengchuan, Fujihara, Yuko, Ogasawara, Toru, Asawa, Yukiyo, Nishizawa, Satoru, Nagata, Satoru, Takato, Tsuyoshi, Hoshi, Kazuto

“…When the chondrocytes are isolated from the native cartilage and proliferate in vitro, they soon lose their original ability to express glycosaminoglycan (GAG)…”
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Recent trends in cartilage regenerative medicine and its application to oral and maxillofacial surgery by Hoshi, Kazuto, Fujihara, Yuko, Asawa, Yukiyo, Nishizawa, Satoru, Kanazawa, Sanshiro, Sakamoto, Tomoaki, Watanabe, Makoto, Ogasawara, Toru, Saijo, Hideto, Mori, Yoshiyuki, Takato, Tsuyoshi

“…▸ Greater progress has been made in the clinical application of cartilage regenerative medicine. ▸ This review overviews the current situation of the cartilage…”
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