Search Results - "Nishiya, Y."

Comparison of mechanism-based inhibition of human cytochrome P450 2C19 by ticlopidine, clopidogrel, and prasugrel by Nishiya, Y., Hagihara, K., Kurihara, A., Okudaira, N., Farid, N.A., Okazaki, O., Ikeda, T.

“…Mechanism-based inhibition of CYP2C19 in human liver microsomes by the thienopyridine antiplatelet agents clopidogrel, prasugrel and their thiolactone…”
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Cold-sensitive ion channels are involved in chilling injury of pig oocytes by Edashige, K., Iwahara, Y., Nariai, S., Nishiya, Y., Kitayama, M., Niimi, S., Seki, S., Koshimoto, C., Matsukawa, K., Kasai, M.

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Effects of organic solvents on the time-dependent inhibition of CYP3A4 by diazepam by Nishiya, Y., Nakamura, K., Okudaira, N., Abe, K., Kobayashi, N., Okazaki, O.

“…The effects of organic solvents, acetonitrile, dimethyl sulfoxide (DMSO), and methanol, which are used to dissolve lipophilic test compounds and cytochrome…”
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A potent 1,4-dihydropyridine L-type calcium channel blocker, benidipine, promotes osteoblast differentiation by Nishiya, Y, Kosaka, N, Uchii, M, Sugimoto, S

“…During their differentiation, osteoblasts sequentially express type I collagen, alkaline phosphatase (ALP), and osteocalcin, and then undergo mineral…”
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Analysis of bacterial glucose dehydrogenase homologs from thermoacidophilic archaeon thermoplasma acidophilum: Finding and characterization of aldohexose dehydrogenase by Nishiya, Y. (Toyobo Co. Ltd., Tsuruga, Fukui (Japan)), Tamura, N, Tamura, T

“…The NADP sup(+)-preferring glucose dehydrogenase from thermoacidophilic archaeon Thermoplasma acidophilum has been characterized, and its crystal structure has…”
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Effects of Various Antihypertensive Drugs on the Function of Osteoblast by NISHIYA, Yoichi, SUGIMOTO, Seiji

“…Several studies have suggested that high blood pressure is associated with the risk of bone loss. Since various antihypertensive drugs are in wide use for the…”
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Improvement of thermal stability of Streptomyces cholesterol oxidase by random mutagenesis and a structural interpretation by Nishiya, Y, Harada, N, Teshima, S I, Yamashita, M, Fujii, I, Hirayama, N, Murooka, Y

“…Random mutagenesis was used to enhance the thermal stability of Streptomyces cholesterol oxidase. Four thermostable mutants were isolated and the following…”
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Analysis of interaction between the Arthrobacter sarcosine oxidase and the coenzyme flavin adenine dinucleotide by site-directed mutagenesis by NISHIYA, Y, IMANAKA, T

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10P DS-6000a, a novel CDH6-targeting antibody-drug conjugate with a novel DNA topoisomerase I inhibitor DXd, demonstrates potent antitumor activity in preclinical models by Suzuki, H., Nagase, S., Saito, C., Nagata, M., Kaneda, Y., Honda, K., Nishiya, Y., Honda, T., Nakada, T., Goto, R., Ishizaka, T., Myobatake, Y., Abe, Y., Agatsuma, T.

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DS-7300a, a novel B7-H3-targeting antibody-drug conjugate with a novel DNA topoisomerase I inhibitor DXd, exhibits potent anti-tumor effects in nonclinical models by Yamato, M., Hasegawa, J., Hattori, C., Maejima, T., Shibutani, T., Deguchi, T., Izumi, N., Watanabe, A., Nishiya, Y., Nakada, T., Abe, Y., Agatsuma, T.

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Cloning and nucleotide sequences of the Bacillus stearothermophilus neutral protease gene and its transcriptional activator gene by NISHIYA, Y, IMANAKA, T

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Huge right atrial myxoma by Sotokawa, M, Nishiya, Y, Hoshino, S, Ueda, T, Saitou, N, Murata, A, Yusa, H, Tateishi, M, Usuda, K, Nagata, Y, Miwa, A, Uchiyama, A

“…Myxomas are account for approximately half of primary cardiac tumors, and 75% cases originate in left atrium. We report our experience of a right atrial…”
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Active site analysis and stabilization of sarcosine oxidase by the substitution of cysteine residues by NISHIYA, Y, ZUIHARA, S, IMANAKA, T

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De Bakey type I aortic dissection complicating systemic lupus erythematosus; report of a case by Murata, A, Nishiya, Y, Saito, N, Konuma, T, Yusa, H, Hoshino, S

“…We report a 43-year-old patient of De Bakey type I aortic dissection [DA (I)] with a 2-year-history of systemic lupus erythematosus (SLE). He had had no…”
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Characterization of a novel BBB-permeable mutant IDH1 inhibitor, DS-1001b by Matsunaga, H., Machida, Y., Nakagawa, M., Yamaguchi, M., Ogawara, Y., Shima, Y., Yamagata, K., Katsumoto, T., Hattori, A., Itoh, M., Seki, T., Nishiya, Y., Nakamura, K., Suzuki, K., Imaoka, T., Suzuki, M., Sampetrean, O., Saya, H., Ichimura, K., Kitabayashi, I.

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396PDCharacterization of a novel BBB-permeable mutant IDH1 inhibitor, DS-1001b by Matsunaga, H, Machida, Y, Nakagawa, M, Yamaguchi, M, Ogawara, Y, Shima, Y, Yamagata, K, Katsumoto, T, Hattori, A, Itoh, M, Seki, T, Nishiya, Y, Nakamura, K, Suzuki, K, Imaoka, T, Suzuki, M, Sampetrean, O, Saya, H, Ichimura, K, Kitabayashi, I

“…Abstract Background Mutations in isocitrate dehydrogenase (IDH) 1 and 2 are frequently observed in glioma, acute myeloid leukemia (AML) and many other cancers…”
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396PD - Characterization of a novel BBB-permeable mutant IDH1 inhibitor, DS-1001b by Matsunaga, H., Machida, Y., Nakagawa, M., Yamaguchi, M., Ogawara, Y., Shima, Y., Yamagata, K., Katsumoto, T., Hattori, A., Itoh, M., Seki, T., Nishiya, Y., Nakamura, K., Suzuki, K., Imaoka, T., Suzuki, M., Sampetrean, O., Saya, H., Ichimura, K., Kitabayashi, I.

“…Mutations in isocitrate dehydrogenase (IDH) 1 and 2 are frequently observed in glioma, acute myeloid leukemia (AML) and many other cancers. While wild-type…”
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Severe tracheal compression resulting from atherosclerotic aortic arch aneurysm; report of a case by Yusa, H, Nishiya, Y, Murata, A, Konuma, T, Saito, N, Hoshino, S

“…A 70-year-old woman presented with severe respiratory insufficiency similar to an asthma attack. Computed tomography (CT) revealed an atherosclerotic aneurysm…”
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Double outlet right ventricle and pulmonary atresia with a birth weight of 1092 g by Murata, Akira, Hoshino, S, Yusa, H, Saito, N, Nishiya, Y, Hatasaki, K

“…A premature infant with double outlet right ventricle and pulmonary atresia with a birth weight of 1092 g is reported. He underwent right modified…”
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Enzymatic Assay for Chloride Ion with Chloride-Dependent Sarcosine Oxidase Created by Site-Directed Mutagenesis by Nishiya, Y., Kawamura, Y., Imanaka, T.

“…Serum chloride ion is routinely assayed in clinical laboratories. We have developed a new enzymatic assay for determining the chloride ion concentration. The…”
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