Search Results - "Nishio, S J"

Lung effects of inhaled corticosteroids in a rhesus monkey model of childhood asthma by Plopper, C. G., Joad, J. P., Miller, L. A., Schelegle, E. S., Fanucchi, M. V., Van Winkle, L. S., Tyler, N. K., Avdalovic, M. V., Evans, M. J., Lasley, W. L., Buckpitt, A. R., Pinkerton, K. E., Tarkington, B. K., Davis, S., Nishio, S. J., Gershwin, L. J., Wu, R., Hyde, D. M.

“…Summary Background The risks for infants and young children receiving inhaled corticosteroid (ICS) therapy are largely unknown. Recent clinical studies…”
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Cellular response in naphthalene-induced Clara cell injury and bronchiolar epithelial repair in mice by Van Winkle, L S, Buckpitt, A R, Nishio, S J, Isaac, J M, Plopper, C G

“…Clara cells, progenitors for bronchiolar epithelium, are also primary targets for metabolically activated pulmonary cytotoxicants and have an abundance of the…”
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The remodelled tracheal basement membrane zone of infant rhesus monkeys after 6 months of recovery by Evans, M. J., Fanucchi, M. V., Baker, G. L., Van Winkle, L. S., Pantle, L. M., Nishio, S. J., Schelegle, E. S., Gershwin, L. J., Miller, L. A., Hyde, D. M., Plopper, C. G.

“…Summary Background In previous studies, we showed that repeated exposure to (1) house dust mite allergen (HDMA) (Dermatophagoides farinae) caused thickening of…”
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Early Events in Naphthalene-Induced Acute Clara Cell Toxicity . II. Comparison of Glutathione Depletion and Histopathology by Airway Location by Plopper, Charles G, Van Winkle, Laura S, Fanucchi, Michelle V, Malburg, Sonia R. C, Nishio, Susan J, Chang, Aimin, Buckpitt, Alan R

“…One of the presumed roles of intracellular glutathione (GSH) is the protection of cells from injury by reactive intermediates produced by the metabolism of…”
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Relationship of cytochrome P-450 activity to Clara cell cytotoxicity. III. Morphometric comparison of changes in the epithelial populations of terminal bronchioles and lobar bronchi in mice, hamsters, and rats after parenteral administration of naphthalene by Plopper, C G, Macklin, J, Nishio, S J, Hyde, D M, Buckpitt, A R

“…The purpose of this study was to define, in quantitative terms, epithelial alterations produced by the cytochrome P-450-activated Clara cell cytotoxicant,…”
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Elevated susceptibility to 4-ipomeanol cytotoxicity in immature Clara cells of neonatal rabbits by Plopper, C G, Weir, A J, Nishio, S J, Chang, A, Voit, M, Philpot, R M, Buckpitt, A R

“…The bronchiolar Clara cell is one of the primary targets in adult mammals for environmental contaminants metabolized by cytochrome P450 (CYP) monooxygenases…”
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Acceleration of alveolar type II cell differentiation in fetal rhesus monkey lung by administration of EGF by Plopper, C G, St George, J A, Read, L C, Nishio, S J, Weir, A J, Edwards, L, Tarantal, A F, Pinkerton, K E, Merritt, T A, Whitsett, J A

“…To examine the effect of epidermal growth factor (EGF) on lung parenchymal maturation in fetal rhesus monkey, recombinant human EGF was administered…”
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The distribution of cytochrome P-450 monooxygenase in cells of the rabbit lung: an ultrastructural immunocytochemical characterization by Serabjit-Singh, C J, Nishio, S J, Philpot, R M, Plopper, C G

“…The cytochrome P-450 monooxygenase system of the mammalian lung is known to be associated with the microsomal subcellular fraction and has been demonstrated in…”
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The role of the nonciliated bronchiolar epithelial (Clara) cell as the progenitor cell during bronchiolar epithelial differentiation in the perinatal rabbit lung by Plopper, C G, Nishio, S J, Alley, J L, Kass, P, Hyde, D M

“…Although it is well established that the nonciliated bronchiolar epithelial (Clara) cell serves as the progenitor for itself and ciliated cells in the adult…”
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Comparison of the distinct effects of epidermal growth factor and betamethasone on the morphogenesis of the gas exchange region and differentiation of alveolar type II cells in lungs of fetal rhesus monkeys by Edwards, L A, Read, L C, Nishio, S J, Weir, A J, Hull, W, Barry, S, Styne, D, Whitsett, J A, Tarantal, A F, George-Nascimento, C

“…To compare the effects of epidermal growth factor (EGF) and betamethasone on the morphogenesis of the gas exchange region and the differentiation of the…”
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Early Events in Naphthalene-Induced Acute Clara Cell Toxicity . Comparison of Membrane Permeability and Ultrastructure by Van Winkle, Laura S, Johnson, Zachary A, Nishio, Susan J, Brown, Collette D, Plopper, Charles G

“…Naphthalene causes severe dose- and site-selective injury to mouse nonciliated bronchiolar (Clara) epithelial cells. Toxicity is characterized by exfoliation…”
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Carbohydrate cytochemistry of tracheobronchial airway epithelium of the rabbit by Plopper, CG, St. George, JA, Nishio, SJ, Etchison, JR, Nettesheim, P

“…Three types of nonciliated secretory epithelial cells contribute to the mucous lining of pulmonary airways: mucous cells, serous cells, and Clara cells…”
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Cellular localization of flavin-containing monooxygenase in rabbit lung by Overby, L, Nishio, S J, Lawton, M P, Plopper, C G, Philpot, R M

“…A specific form of flavin monooxygenase has been identified in the lungs of a number of species. Distribution of the pulmonary flavin-containing monooxygenase…”
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Neonatal Clara cell toxicity by 4-ipomeanol alters bronchiolar organization in adult rabbits by Smiley-Jewell, S M, Nishio, S J, Weir, A J, Plopper, C G

“…Nonciliated bronchiolar (Clara) cells metabolize environmental toxicants, are progenitor cells during development, and differentiate postnatally. Because…”
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Carbohydrate cytochemistry of rhesus monkey tracheal submucosal glands by St George, J A, Nishio, S J, Cranz, D L, Plopper, C G

“…This study was designed to characterize the ultrastructure and carbohydrate content of secretory cells in submucosal glands of rhesus monkey and to compare…”
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Comparison of nonciliated tracheal epithelial cells in six mammalian species: ultrastructure and population densities by Plopper, C G, Mariassy, A T, Wilson, D W, Alley, J L, Nishio, S J, Nettesheim, P

“…Three types of nonciliated epithelial cells in mammalian conducting respiratory airways are thought to be secretory: mucous (goblet) cells, serous epithelial…”
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Tracheal submucosal gland development in the rhesus monkey, Macaca mulatta: ultrastructure and histochemistry by Plopper, C G, Weir, A J, Nishio, S J, Cranz, D L, St George, J A

“…The submucosal glands are thought to be the primary source of the mucus overlying the primate trachea and conducting airways. This study characterizes the…”
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Tracheobronchial epithelium of the sheep: III. Carbohydrate histochemical and cytochemical characterization of secretory epithelial cells by Mariassy, A T, St George, J A, Nishio, S J, Plopper, C G

“…We examined histochemically (light microscopy-LM) and cytochemically (electron microscopy-EM) the secretory epithelial cells in the tracheobronchial mucosa of…”
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Carbohydrate cytochemistry of rhesus monkey tracheal epithelium by St George, J A, Nishio, S J, Plopper, C G

“…Three types of nonciliated secretory epithelial cells contribute material to the mucous lining of pulmonary airways: mucous cells, serous cells, and Clara…”
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Atypical development of the tracheal basement membrane zone of infant rhesus monkeys exposed to ozone and allergen by Evans, Michael J, Fanucchi, Michelle V, Baker, Gregory L, Van Winkle, Laura S, Pantle, Lorraine M, Nishio, Susan J, Schelegle, Edward S, Gershwin, Laurel J, Miller, Lisa A, Hyde, Dallas M, Sannes, Philip L, Plopper, Charles G

“…Development of the basement membrane zone (BMZ) occurs postnatally in the rhesus monkey. The purpose of this study was to determine whether house dust mite…”
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