Search Results - "Nishimura, Erin Osborne"

A Transcriptional Lineage of the Early C. elegans Embryo by Tintori, Sophia C., Osborne Nishimura, Erin, Golden, Patrick, Lieb, Jason D., Goldstein, Bob

“…During embryonic development, cells must establish fates, morphologies, and behaviors in coordination with one another to form a functional body. A prevalent…”
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Evidence for extensive horizontal gene transfer from the draft genome of a tardigrade by Boothby, Thomas C., Tenlen, Jennifer R., Smith, Frank W., Wang, Jeremy R., Patanella, Kiera A., Nishimura, Erin Osborne, Tintori, Sophia C., Li, Qing, Jones, Corbin D., Yandell, Mark, Messina, David N., Glasscock, Jarret, Goldstein, Bob

“…Horizontal gene transfer (HGT), or the transfer of genes between species, has been recognized recently as more pervasive than previously suspected. Here, we…”
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LCD-Composer: an intuitive, composition-centric method enabling the identification and detailed functional mapping of low-complexity domains by Cascarina, Sean M, King, David C, Osborne Nishimura, Erin, Ross, Eric D

“…Abstract Low complexity domains (LCDs) in proteins are regions predominantly composed of a small subset of the possible amino acids. LCDs are involved in a…”
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Asymmetric transcript discovery by RNA-seq in C. elegans blastomeres identifies neg-1, a gene important for anterior morphogenesis by Osborne Nishimura, Erin, Zhang, Jay C, Werts, Adam D, Goldstein, Bob, Lieb, Jason D

“…After fertilization but prior to the onset of zygotic transcription, the C. elegans zygote cleaves asymmetrically to create the anterior AB and posterior P1…”
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RNA-seq in the tetraploid Xenopus laevis enables genome-wide insight in a classic developmental biology model organism by Amin, Nirav M., Tandon, Panna, Osborne Nishimura, Erin, Conlon, Frank L.

“…Advances in sequencing technology have significantly advanced the landscape of developmental biology research. The dissection of genetic networks in model and…”
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TIR domains of plant immune receptors are NAD + -cleaving enzymes that promote cell death by Wan, Li, Essuman, Kow, Anderson, Ryan G, Sasaki, Yo, Monteiro, Freddy, Chung, Eui-Hwan, Osborne Nishimura, Erin, DiAntonio, Aaron, Milbrandt, Jeffrey, Dangl, Jeffery L, Nishimura, Marc T

“…Plant nucleotide-binding leucine-rich repeat (NLR) immune receptors activate cell death and confer disease resistance by unknown mechanisms. We demonstrate…”
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Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism by Saha, Shambaditya, Weber, Christoph A., Nousch, Marco, Adame-Arana, Omar, Hoege, Carsten, Hein, Marco Y., Osborne-Nishimura, Erin, Mahamid, Julia, Jahnel, Marcus, Jawerth, Louise, Pozniakovski, Andrej, Eckmann, Christian R., Jülicher, Frank, Hyman, Anthony A.

“…P granules are non-membrane-bound RNA-protein compartments that are involved in germline development in C. elegans. They are liquids that condense at one end…”
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TIR-only protein RBA1 recognizes a pathogen effector to regulate cell death in Arabidopsis by Nishimura, Marc T., Anderson, Ryan G., Cherkis, Karen A., Law, Terry F., Liu, Qingli L., Machius, Mischa, Nimchuk, Zachary L., Yang, Li, Chung, Eui-Hwan, Kasmi, Farid El, Hyunh, Michael, Nishimura, Erin Osborne, Sondek, John E., Dangl, Jeffery L.

“…Detection of pathogens by plants is mediated by intracellular nucleotide-binding site leucine-rich repeat (NLR) receptor proteins. NLR proteins are defined by…”
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The enigmatic conservation of a Rap1 binding site in the Saccharomyces cerevisiae HMR-E silencer by Teytelman, Leonid, Osborne Nishimura, Erin A, Özaydin, Bilge, Eisen, Michael B, Rine, Jasper

“…Silencing at the HMR and HML loci in Saccharomyces cerevisiae requires recruitment of Sir proteins to the HML and HMR silencers. The silencers are regulatory…”
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It’s Just a Phase: Exploring the Relationship Between mRNA, Biomolecular Condensates, and Translational Control by Parker, Dylan M., Winkenbach, Lindsay P., Osborne Nishimura, Erin

“…Cells spatially organize their molecular components to carry out fundamental biological processes and guide proper development. The spatial organization of RNA…”
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Hyper-active RAS/MAPK introduces cancer-specific mitotic vulnerabilities by Herman, Jacob A, Romain, Romario R, Hoellerbauer, Pia, Shirnekhi, Hazheen K, King, David C, DeLuca, Keith F, Osborne Nishimura, Erin, Paddison, Patrick J, DeLuca, Jennifer G

“…Aneuploidy, the incorrect number of whole chromosomes, is a common feature of tumors that contributes to their initiation and evolution. Preventing aneuploidy…”
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mRNA localization is linked to translation regulation in the Caenorhabditis elegans germ lineage by Parker, Dylan M, Winkenbach, Lindsay P, Boyson, Sam, Saxton, Matthew N, Daidone, Camryn, Al-Mazaydeh, Zainab A, Nishimura, Marc T, Mueller, Florian, Osborne Nishimura, Erin

“…early embryos generate cell-specific transcriptomes despite lacking active transcription, thereby presenting an opportunity to study mechanisms of…”
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Quantitating transcription factor redundancy: The relative roles of the ELT-2 and ELT-7 GATA factors in the C. elegans endoderm by Dineen, Aidan, Osborne Nishimura, Erin, Goszczynski, Barbara, Rothman, Joel H., McGhee, James D.

“…The two GATA transcription factors ELT-2 and ELT-7 function in the differentiation of the C. elegans intestine. ELT-2 loss causes lethality. ELT-7 loss causes…”
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Transcriptome profiling of the Caenorhabditis elegans intestine reveals that ELT-2 negatively and positively regulates intestinal gene expression within the context of a gene regulatory network by Williams, Robert T P, King, David C, Mastroianni, Izabella R, Hill, Jessica L, Apenes, Nicolai W, Ramirez, Gabriela, Miner, E Catherine, Moore, Andrew, Coleman, Karissa, Nishimura, Erin Osborne

“…Abstract ELT-2 is the major transcription factor (TF) required for Caenorhabditis elegans intestinal development. ELT-2 expression initiates in embryos to…”
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The function and regulation of the GATA factor ELT-2 in the C. elegans endoderm by Wiesenfahrt, Tobias, Berg, Janette Y, Osborne Nishimura, Erin, Robinson, Adam G, Goszczynski, Barbara, Lieb, Jason D, McGhee, James D

“…ELT-2 is the major regulator of genes involved in differentiation, maintenance and function of C. elegans intestine from the early embryo to mature adult…”
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Hand Dissection of Caenorhabditis elegans Intestines by Hill, Jessica L, Moore, Andrew, Williams, Robert T P, Osborne Nishimura, Erin

“…Comprised of only 20 cells, the Caenorhabditis elegans intestine is the nexus of many life-supporting functions, including digestion, metabolism, aging,…”
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Improved Methods for Single-Molecule Fluorescence In Situ Hybridization and Immunofluorescence in Caenorhabditis elegans Embryos by Parker, Dylan M, Winkenbach, Lindsay P, Parker, Annemarie, Boyson, Sam, Nishimura, Erin Osborne

“…Visualization of gene products in Caenorhabditis elegans has provided insights into the molecular and biological functions of many novel genes in their native…”
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A Strategy To Isolate Modifiers of Caenorhabditis elegans Lethal Mutations: Investigating the Endoderm Specifying Ability of the Intestinal Differentiation GATA Factor ELT-2 by Wiesenfahrt, Tobias, Duanmu, Jingjie, Snider, Frances, Moerman, Don, Au, Vinci, Li-Leger, Erica, Flibotte, Stephane, Parker, Dylan M, Marshall, Craig J, Nishimura, Erin Osborne, Mains, Paul E, McGhee, James D

“…The ELT-2 GATA factor normally functions in differentiation of the endoderm, downstream of endoderm specification. We have previously shown that, if ELT-2 is…”
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The ERM-1 membrane-binding domain directs erm-1 mRNA localization to the plasma membrane in the C. elegans embryo by Winkenbach, Lindsay P, Parker, Dylan M, Williams, Robert T P, Nishimura, Erin Osborne

“…mRNA localization and transport are integral in regulating gene expression. In Caenorhabditis elegans embryos, the maternally inherited mRNA erm-1…”
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Widespread roles for piRNAs and WAGO-class siRNAs in shaping the germline transcriptome of Caenorhabditis elegans by Reed, Kailee J, Svendsen, Joshua M, Brown, Kristen C, Montgomery, Brooke E, Marks, Taylor N, Vijayasarathy, Tarah, Parker, Dylan M, Nishimura, Erin Osborne, Updike, Dustin L, Montgomery, Taiowa A

“…Piwi-interacting RNAs (piRNAs) and small interfering RNAs (siRNAs) are distinct classes of small RNAs required for proper germline development. To identify the…”
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