Search Results - "Nishikii, Hidekazu"

Chemically defined cytokine-free expansion of human haematopoietic stem cells by Sakurai, Masatoshi, Ishitsuka, Kantaro, Ito, Ryoji, Wilkinson, Adam C., Kimura, Takaharu, Mizutani, Eiji, Nishikii, Hidekazu, Sudo, Kazuhiro, Becker, Hans Jiro, Takemoto, Hiroshi, Sano, Tsubasa, Kataoka, Keisuke, Takahashi, Satoshi, Nakamura, Yukio, Kent, David G., Iwama, Atsushi, Chiba, Shigeru, Okamoto, Shinichiro, Nakauchi, Hiromitsu, Yamazaki, Satoshi

“…Haematopoietic stem cells (HSCs) are a rare cell type that reconstitute the entire blood and immune systems after transplantation and can be used as a curative…”
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A single-cell atlas of non-haematopoietic cells in human lymph nodes and lymphoma reveals a landscape of stromal remodelling by Abe, Yoshiaki, Sakata-Yanagimoto, Mamiko, Fujisawa, Manabu, Miyoshi, Hiroaki, Suehara, Yasuhito, Hattori, Keiichiro, Kusakabe, Manabu, Sakamoto, Tatsuhiro, Nishikii, Hidekazu, Nguyen, Tran B., Owada, Yohei, Enomoto, Tsuyoshi, Sawa, Aya, Bando, Hiroko, Yoshida, Chikashi, Tabata, Rikako, Terao, Toshiki, Nakayama, Masahiro, Ohshima, Koichi, Usuki, Kensuke, Oda, Tatsuya, Matsue, Kosei, Chiba, Shigeru

“…The activities of non-haematopoietic cells (NHCs), including mesenchymal stromal cells and endothelial cells, in lymphomas are reported to underlie…”
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Clinical significance of disease‐specific MYD88 mutations in circulating DNA in primary central nervous system lymphoma by Hattori, Keiichiro, Sakata‐Yanagimoto, Mamiko, Suehara, Yasuhito, Yokoyama, Yasuhisa, Kato, Takayasu, Kurita, Naoki, Nishikii, Hidekazu, Obara, Naoshi, Takano, Shingo, Ishikawa, Eiichi, Matsumura, Akira, Hasegawa, Yuichi, Chiba, Shigeru

“…Recent sequencing studies demonstrated the MYD88 L265P mutation in more than 70% of primary central nervous system lymphomas (PCNSL), and the clinical…”
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A PET Imaging Strategy to Visualize Activated T Cells in Acute Graft-versus-Host Disease Elicited by Allogenic Hematopoietic Cell Transplant by Ronald, John A, Kim, Byung-Su, Gowrishankar, Gayatri, Namavari, Mohammad, Alam, Israt S, D'Souza, Aloma, Nishikii, Hidekazu, Chuang, Hui-Yen, Ilovich, Ohad, Lin, Chih-Feng, Reeves, Robert, Shuhendler, Adam, Hoehne, Aileen, Chan, Carmel T, Baker, Jeanette, Yaghoubi, Shahriar S, VanBrocklin, Henry F, Hawkins, Randall, Franc, Benjamin L, Jivan, Salma, Slater, James B, Verdin, Emily F, Gao, Kenneth T, Benjamin, Jonathan, Negrin, Robert, Gambhir, Sanjiv Sam

“…A major barrier to successful use of allogeneic hematopoietic cell transplantation is acute graft-versus-host disease (aGVHD), a devastating condition that…”
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SINC-seq: correlation of transient gene expressions between nucleus and cytoplasm reflects single-cell physiology by Abdelmoez, Mahmoud N, Iida, Kei, Oguchi, Yusuke, Nishikii, Hidekazu, Yokokawa, Ryuji, Kotera, Hidetoshi, Uemura, Sotaro, Santiago, Juan G, Shintaku, Hirofumi

“…We report a microfluidic system that physically separates nuclear RNA (nucRNA) and cytoplasmic RNA (cytRNA) from a single cell and enables single-cell…”
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18FDG-PET imaging and histopathology in neuroleukemiosis with acute myeloid leukemia by Kiyoki, Yusuke, Matsuoka, Ryota, Kaneta, Tomohiro, Nishikii, Hidekazu

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The fatty acid elongase Elovl6 is crucial for hematopoietic stem cell engraftment and leukemia propagation by Kiyoki, Yusuke, Kato, Takayasu, Kito, Sakura, Matsuzaka, Takashi, Morioka, Shin, Sasaki, Junko, Makishima, Kenichi, Sakamoto, Tatsuhiro, Nishikii, Hidekazu, Obara, Naoshi, Sakata-Yanagimoto, Mamiko, Sasaki, Takehiko, Shimano, Hitoshi, Chiba, Shigeru

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High-throughput mechanical phenotyping and transcriptomics of single cells by Shiomi, Akifumi, Kaneko, Taikopaul, Nishikawa, Kaori, Tsuchida, Arata, Isoshima, Takashi, Sato, Mayuko, Toyooka, Kiminori, Doi, Kentaro, Nishikii, Hidekazu, Shintaku, Hirofumi

“…The molecular system regulating cellular mechanical properties remains unexplored at single-cell resolution mainly due to a limited ability to combine…”
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Foxp3+ regulatory T cells maintain the bone marrow microenvironment for B cell lymphopoiesis by Pierini, Antonio, Nishikii, Hidekazu, Baker, Jeanette, Kimura, Takaharu, Kwon, Hye-Sook, Pan, Yuqiong, Chen, Yan, Alvarez, Maite, Strober, William, Velardi, Andrea, Shizuru, Judith A., Wu, Joy Y., Chiba, Shigeru, Negrin, Robert S.

“…Foxp3 + regulatory T cells (Treg cells) modulate the immune system and maintain self-tolerance, but whether they affect haematopoiesis or haematopoietic stem…”
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Triple-negative Thrombocythemia and Subsequent Acute Lymphoblastic Leukemia with Additional Somatic Mutations by Tsuboi, Yuri, Sakamoto, Tatsuhiro, Makishima, Kenichi, Suehara, Yasuhito, Hattori, Keiichiro, Kurita, Naoki, Yokoyama, Yasuhisa, Kato, Takayasu, Nishikii, Hidekazu, Obara, Naoshi, Matsumura, Fumiaki, Matsuoka, Ryota, Chiba, Shigeru, Sakata-Yanagimoto, Mamiko

“…Triple-negative essential thrombocythemia (ET) is a condition in which mutations in JAK2, CALR and MPL are all negative. Transformation to acute myeloid…”
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Liquid biopsy for the identification of intravascular large B-cell lymphoma by Suehara, Yasuhito, Sakata-Yanagimoto, Mamiko, Hattori, Keiichiro, Nanmoku, Toru, Itoh, Takayoshi, Kaji, Daisuke, Yamamoto, Go, Abe, Yoshiaki, Narita, Kentaro, Takeuchi, Masami, Matsue, Kosei, Sato, Taiki, Noguchi, Masayuki, Baba, Naoko, Sakamoto, Tatsuhiro, Kusakabe, Manabu, Kurita, Naoki, Kato, Takayasu, Yokoyama, Yasuhisa, Nishikii, Hidekazu, Obara, Naoshi, Hasegawa, Yuichi, Chiba, Shigeru

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Hemolysis induced by SARS-CoV-2 mRNA vaccination in patients with paroxysmal nocturnal hemoglobinuria by Kamura, Yuya, Sakamoto, Tatsuhiro, Yokoyama, Yasuhisa, Nishikii, Hidekazu, Sakata-Yanagimoto, Mamiko, Chiba, Shigeru, Obara, Naoshi

“…Autoimmune and complement-related hematological side effects have been observed with messenger ribonucleic acid (mRNA) vaccines. Here, we report the incidence…”
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On-Chip Separation and Analysis of RNA and DNA from Single Cells by Shintaku, Hirofumi, Nishikii, Hidekazu, Marshall, Lewis A, Kotera, Hidetoshi, Santiago, Juan G

“…The simultaneous analysis of RNA and DNA of single cells remains a challenge as these species have very similar physical and biochemical properties and can…”
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Salvage Cord Blood Transplantation Using a Short-term Reduced-intensity Conditioning Regimen for Graft Failure by Suma, Sakurako, Yokoyama, Yasuhisa, Momose, Haruka, Makishima, Kenichi, Kiyoki, Yusuke, Sakamoto, Tatsuhiro, Kusakabe, Manabu, Kato, Takayasu, Kurita, Naoki, Nishikii, Hidekazu, Sakata-Yanagimoto, Mamiko, Obara, Naoshi, Hasegawa, Yuichi, Chiba, Shigeru

“…Objective Graft failure (GF) is a life-threatening complication of hematopoietic stem cell transplantation (HSCT). A standardized conditioning regimen and an…”
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Unipotent Megakaryopoietic Pathway Bridging Hematopoietic Stem Cells and Mature Megakaryocytes by Nishikii, Hidekazu, Kanazawa, Yosuke, Umemoto, Terumasa, Goltsev, Yury, Matsuzaki, Yu, Matsushita, Kenji, Yamato, Masayuki, Nolan, Garry P., Negrin, Robert, Chiba, Shigeru

“…Recent identification of platelet/megakaryocyte‐biased hematopoietic stem/repopulating cells requires revision of the intermediate pathway for…”
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Cardiac Tamponade as a Recurrence of Angioimmunoblastic T-Cell Lymphoma with the Detection of a p.Gly17Val RHOA Mutation in the Pericardial Effusion by Tsuboi, Yuri, Iimura, Yumoe, Matsumura, Fumiaki, Nanmoku, Toru, Suma, Sakurako, Matsuoka, Ryota, Nakagawa, Tomoki, Nakagawa, Daishi, Suehara, Yasuhito, Hattori, Keiichiro, Sato, Kimi, Maruyama, Yumiko, Sakamoto, Tatsuhiro, Yokoyama, Yasuhisa, Kato, Takayasu, Kurita, Naoki, Nishikii, Hidekazu, Obara, Naoshi, Ieda, Masaki, Chiba, Shigeru, Sakata-Yanagimoto, Mamiko

“…Angioimmunoblastic T-cell lymphoma (AITL) is an intractable type of T-cell lymphoma. We and others have identified that the p.Gly17Val RHOA mutation is…”
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Treatment with agonistic DR3 antibody results in expansion of donor Tregs and reduced graft-versus-host disease by Kim, Byung-Su, Nishikii, Hidekazu, Baker, Jeanette, Pierini, Antonio, Schneidawind, Dominik, Pan, Yuqiong, Beilhack, Andreas, Park, Chung-Gyu, Negrin, Robert S.

“…The paucity of regulatory T cells (Tregs) limits clinical translation to control aberrant immune reactions including graft-versus-host disease (GVHD). Recent…”
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Notch Signaling in Nestin‐Expressing Cells in the Bone Marrow Maintains Erythropoiesis via Macrophage Integrity by Sakamoto, Tatsuhiro, Obara, Naoshi, Nishikii, Hidekazu, Kato, Takayasu, Cao‐Sy, Luan, Fujimura, Ryosuke, Yagita, Hideo, Sakata‐Yanagimoto, Mamiko, Takahashi, Satoru, Chiba, Shigeru

“…Notch signaling plays pivotal roles in both hematopoietic stem/progenitor and their niche cells. Myeloproliferative phenotypes are induced by disruption of…”
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Early administration of cyclosporine may reduce the incidence of cytokine release syndrome after HLA-haploidentical hematopoietic stem-cell transplantation with post-transplant cyclophosphamide by Kurita, Naoki, Sakamoto, Tatsuhiro, Kato, Takayasu, Kusakabe, Manabu, Yokoyama, Yasuhisa, Nishikii, Hidekazu, Sakata-Yanagimoto, Mamiko, Obara, Naoshi, Hasegawa, Yuichi, Chiba, Shigeru

“…Cytokine release syndrome (CRS), occurring in more than 70% of HLA-haploidentical hematopoietic stem-cell transplantations with post-transplant…”
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Activation of the DR3-TL1A Axis in Donor Mice Leads to Regulatory T Cell Expansion and Activation With Reduction in Graft-Versus-Host Disease by Mavers, Melissa, Simonetta, Federico, Nishikii, Hidekazu, Ribado, Jessica V, Maas-Bauer, Kristina, Alvarez, Maite, Hirai, Toshihito, Turkoz, Mustafa, Baker, Jeanette, Negrin, Robert S

“…Death receptor 3 (DR3) is a tumor necrosis factor receptor superfamily member (TNFRSF25), which is minimally expressed on resting conventional T cells (though…”
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