Search Results - "Nishikawa, Kiisa C"
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Comparative analysis of the transcriptomes of EDL, psoas, and soleus muscles from mice
Published in BMC genomics (19-11-2020)“…Individual skeletal muscles have evolved to perform specific tasks based on their molecular composition. In general, muscle fibers are characterized as either…”
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Transcriptomic profiles of muscular dystrophy with myositis (mdm) in extensor digitorum longus, psoas, and soleus muscles from mice
Published in BMC genomics (17-09-2022)“…Abstract Background Titinopathies are inherited muscular diseases triggered by genetic mutations in the titin gene. Muscular dystrophy with myositis ( mdm ) is…”
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Physiological Mechanisms of Eccentric Contraction and Its Applications: A Role for the Giant Titin Protein
Published in Frontiers in physiology (09-02-2017)“…When active muscles are stretched, our understanding of muscle function is stretched as well. Our understanding of the molecular mechanisms of concentric…”
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Effects of a titin mutation on negative work during stretch-shortening cycles in skeletal muscles
Published in Journal of experimental biology (15-11-2017)“…Negative work occurs in muscles during braking movements such as downhill walking or landing after a jump. When performing negative work during…”
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Is titin a ‘winding filament’? A new twist on muscle contraction
Published in Proceedings of the Royal Society. B, Biological sciences (07-03-2012)“…Recent studies have demonstrated a role for the elastic protein titin in active muscle, but the mechanisms by which titin plays this role remain to be…”
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Non-cross Bridge Viscoelastic Elements Contribute to Muscle Force and Work During Stretch-Shortening Cycles: Evidence From Whole Muscles and Permeabilized Fibers
Published in Frontiers in physiology (29-03-2021)“…The sliding filament-swinging cross bridge theory of skeletal muscle contraction provides a reasonable description of muscle properties during isometric…”
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Basic science and clinical use of eccentric contractions: History and uncertainties
Published in Journal of sport and health science (01-07-2018)“…•Eccentric contractions conform poorly to accepted models of muscle function.•The function of elastic proteins, ubiquitous in animal muscle, has been…”
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Residual force enhancement is reduced in permeabilized fiber bundles from mdm muscles
Published in Journal of experimental biology (15-05-2022)“…Residual force enhancement (RFE) is the increase in steady-state force after active stretch relative to the force during isometric contraction at the same…”
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Case Study: A Bio-Inspired Control Algorithm for a Robotic Foot-Ankle Prosthesis Provides Adaptive Control of Level Walking and Stair Ascent
Published in Frontiers in robotics and AI (11-04-2018)“…Powered ankle-foot prostheses assist users through plantarflexion during stance and dorsiflexion during swing. Provision of motor power permits faster…”
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Effects of a titin mutation on force enhancement and force depression in mouse soleus muscles
Published in Journal of experimental biology (27-01-2020)“…The active isometric force produced by muscles varies with muscle length in accordance with the force-length relationship. Compared with isometric contractions…”
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Optimal length, calcium sensitivity and twitch characteristics of skeletal muscles from mdm mice with a deletion in N2A titin
Published in Journal of experimental biology (17-06-2019)“…During isometric contractions, the optimal length of skeletal muscles increases with decreasing activation. The underlying mechanism for this phenomenon is…”
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Muscle Function from Organisms to Molecules
Published in Integrative and comparative biology (01-08-2018)“…Gaps in our understanding of muscle contraction at the molecular level limit the ability to predict in vivo muscle forces in humans and animals during natural…”
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The evolution of bite force in horned lizards: the influence of dietary specialization
Published in Journal of anatomy (01-02-2018)“…Dietary specialization is an important driver of the morphology and performance of the feeding system in many organisms, yet the evolution of phenotypic…”
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Effects of activation on the elastic properties of intact soleus muscles with a deletion in titin
Published in Journal of experimental biology (01-03-2017)“…Titin has long been known to contribute to muscle passive tension. Recently, it was also demonstrated that titin-based stiffness increases upon Ca activation…”
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Severe thermoregulatory deficiencies in mice with a deletion in the titin gene TTN
Published in Journal of experimental biology (30-04-2019)“…Muscular dystrophy with myositis ( ) mice carry a deletion in the N2A region of the gene for the muscle protein titin ( ), shiver at low frequency, fail to…”
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Shiver me titin! Elucidating titin's role in shivering thermogenesis
Published in Journal of experimental biology (01-03-2015)“…Shivering frequency scales predictably with body mass and is 10 times higher in a mouse than a moose. The link between shivering frequency and body mass may…”
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The Hip-twist Jump: A Unique Mechanism for Jumping in Lungless Salamanders
Published in Journal of herpetology (01-12-2017)“…Many terrestrial and aquatic animals jump to escape predators. Most terrestrial animals use robust hindlimbs to produce the power needed to lift their bodies…”
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The effects of a skeletal muscle titin mutation on walking in mice
Published in Journal of Comparative Physiology (2017)“…Titin contributes to sarcomere assembly, muscle signaling, and mechanical properties of muscle. The mdm mouse exhibits a small deletion in the titin gene…”
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Aquatic feeding in pipid frogs: the use of suction for prey capture
Published in Journal of experimental biology (15-06-2010)“…Inertial suction feeding is the most common method of prey capture among aquatic vertebrates. However, it had been unclear whether the aquatic frogs in the…”
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Storage and recovery of elastic potential energy powers ballistic prey capture in toads
Published in Journal of experimental biology (01-07-2006)“…Ballistic tongue projection in toads is a remarkably fast and powerful movement. The goals of this study were to: (1) quantify in vivo power output and…”
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