Search Results - "Nishida, Keigo"

Zinc Suppresses Colorectal Cancer Development through Cell-mediated Immunity by Nishida, Keigo, Nakagawa, Naoya

“…Zinc is one of the essential trace elements, and is involved in various functions in the body. Zinc deficiency is known to cause immune abnormalities, but the…”
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Role of Zinc Signaling in the Regulation of Mast Cell-, Basophil-, and T Cell-Mediated Allergic Responses by Nishida, Keigo, Uchida, Ryota

“…Zinc is essential for maintaining normal structure and physiological function of cells. Its deficiency causes growth retardation, immunodeficiency, and…”
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Inhibitory Effect of Zinc on Colorectal Cancer by Granzyme B Transcriptional Regulation in Cytotoxic T Cells by Nakagawa, Naoya, Fujisawa, Yutaka, Xiang, Huihui, Kitamura, Hidemitsu, Nishida, Keigo

“…Zinc is one of the essential trace elements and is involved in various functions in the body. Zinc deficiency is known to cause immune abnormalities, but the…”
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Essential function for the calcium sensor STIM1 in mast cell activation and anaphylactic responses by Kurosaki, Tomohiro, Baba, Yoshihiro, Nishida, Keigo, Fujii, Yoko, Hirano, Toshio, Hikida, Masaki

“…Mast cells have key functions as effectors of immunoglobulin E–mediated allergic inflammatory diseases. Allergen stimulation induces Ca 2+ influx and elicits…”
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The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors by Nishida, Keigo, Hirano, Toshio

“…The Grb2‐associated binder (Gab) family adapter proteins are scaffolding adapter molecules that display sequence similarity with Drosophila DOS (daughter of…”
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AdamB: Decoupled Bayes by Backprop with Gaussian Scale Mixture Prior by Nishida, Keigo, Taiji, Makoto

“…Overfitting of neural networks to training data is one of the most significant problems in machine learning. Bayesian neural networks (BNNs) are known to be…”
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A single fast Hebbian-like process enabling one-shot class addition in deep neural networks without backbone modification by Hosoda, Kazufumi, Nishida, Keigo, Seno, Shigeto, Mashita, Tomohiro, Kashioka, Hideki, Ohzawa, Izumi

“…One-shot learning, the ability to learn a new concept from a single instance, is a distinctive brain function that has garnered substantial interest in machine…”
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L-Type Calcium Channel-Mediated Zinc Wave Is Involved in the Regulation of IL-6 by Stimulating Non-IgE with LPS and IL-33 in Mast Cells and Dendritic Cells by Uchida, Ryota, Xiang, Huihui, Arai, Hiroya, Kitamura, Hidemitsu, Nishida, Keigo

“…The trace element zinc is essential for the immune system, and its dysregulation and deficiency results in impaired immune function. Recent studies have shown…”
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Essential Role for Zinc Transporter 2 (ZnT2)-mediated Zinc Transport in Mammary Gland Development and Function during Lactation by Lee, Sooyeon, Hennigar, Stephen R., Alam, Samina, Nishida, Keigo, Kelleher, Shannon L.

“…The zinc transporter ZnT2 (SLC30A2) imports zinc into vesicles in secreting mammary epithelial cells (MECs) and is critical for zinc efflux into milk during…”
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Zinc is a novel intracellular second messenger by Yamasaki, Satoru, Sakata-Sogawa, Kumiko, Hasegawa, Aiko, Suzuki, Tomoyuki, Kabu, Koki, Sato, Emi, Kurosaki, Tomohiro, Yamashita, Susumu, Tokunaga, Makio, Nishida, Keigo, Hirano, Toshio

“…Zinc is an essential trace element required for enzymatic activity and for maintaining the conformation of many transcription factors; thus, zinc homeostasis…”
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Identification of 5-Hydroxymethylfurfural (5-HMF) as an Active Component Citrus Jabara That Suppresses FcεRI-Mediated Mast Cell Activation by Uchida, Ryota, Kato, Michiko, Hattori, Yuka, Kikuchi, Hiroko, Watanabe, Emi, Kobayashi, Katsuumi, Nishida, Keigo

“…Jabara ( Hort. ex Y. Tanaka) is a type of citrus fruit known for its beneficial effect against seasonal allergies. Jabara is rich in the antioxidant narirutin…”
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Crucial role for autophagy in degranulation of mast cells by Ushio, Hiroko, PhD, Ueno, Takashi, PhD, Kojima, Yuko, PhD, Komatsu, Masaaki, PhD, Tanaka, Satoshi, PhD, Yamamoto, Akitsugu, PhD, Ichimura, Yoshinobu, PhD, Ezaki, Junji, PhD, Nishida, Keigo, PhD, Komazawa-Sakon, Sachiko, BD, Niyonsaba, François, PhD, Ishii, Tetsuro, PhD, Yanagawa, Toru, DDS, MD, PhD, Kominami, Eiki, MD, PhD, Ogawa, Hideoki, MD, PhD, Okumura, Ko, MD, PhD, Nakano, Hiroyasu, MD, PhD

“…Background Autophagy plays a crucial role in controlling various biological responses including starvation, homeostatic turnover of long-lived proteins, and…”
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Reductive methylation of triphthaloylbenzene: Isolation and characterization of hexamethoxy-trinaphthylene and two unexpected trinaphthylene derivatives by Nishida, Keigo, Ono, Katsuhiko, Kato, Shin-ichiro, Kitamura, Chitoshi

“…[Display omitted] •Reductive methylation of triphthaloylbenezene was complicated.•Two unexpected products except for hexamethoxy-trinaphthylene were…”
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Severe pulmonary hypertension with fibrodysplasia ossificans progressiva by Nishida, Keigo, Ikawa, Yasuhiro, Nakamura, Taichi, Ohta, Kunio, Wada, Taizo

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Roles of zinc and zinc signaling in immunity: zinc as an intracellular signaling molecule by Hirano, Toshio, Murakami, Masaaki, Fukada, Toshiyuki, Nishida, Keigo, Yamasaki, Satoru, Suzuki, Tomoyuki

“…Zinc (Zn) is an essential nutrient required for cell growth, differentiation, and survival, and its deficiency causes growth retardation, immunodeficiency, and…”
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Catheter ablation in a pediatric patient with idiopathic ventricular tachycardia and arrhythmia‐induced cardiomyopathy by Fujita, Shuhei, Nishida, Keigo, Chikata, Akio, Usuda, Kazuo, Hatasaki, Kiyoshi

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Hyperactivation of JAK1 tyrosine kinase induces stepwise, progressive pruritic dermatitis by Yasuda, Takuwa, Fukada, Toshiyuki, Nishida, Keigo, Nakayama, Manabu, Matsuda, Masashi, Miura, Ikuo, Dainichi, Teruki, Fukuda, Shinji, Kabashima, Kenji, Nakaoka, Shinji, Bin, Bum-Ho, Kubo, Masato, Ohno, Hiroshi, Hasegawa, Takanori, Ohara, Osamu, Koseki, Haruhiko, Wakana, Shigeharu, Yoshida, Hisahiro

“…Skin homeostasis is maintained by the continuous proliferation and differentiation of epidermal cells. The skin forms a strong but flexible barrier against…”
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A novel role of the L-type calcium channel α1D subunit as a gatekeeper for intracellular zinc signaling: zinc wave by Yamasaki, Satoru, Hasegawa, Aiko, Hojyo, Shintaro, Ohashi, Wakana, Fukada, Toshiyuki, Nishida, Keigo, Hirano, Toshio

“…Recent studies have shown that zinc ion (Zn) can behave as an intracellular signaling molecule. We previously demonstrated that mast cells stimulated through…”
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Critical role of P1-Runx1 in mouse basophil development by Mukai, Kaori, BenBarak, Maya J., Tachibana, Masashi, Nishida, Keigo, Karasuyama, Hajime, Taniuchi, Ichiro, Galli, Stephen J.

“…Runx1P1N/P1N mice are deficient in the transcription factor distal promoter-derived Runt-related transcription factor 1 (P1-Runx1) and have a > 90% reduction…”
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Transepidermal Water Loss (TEWL)-decreasing Effect by Administration of Zinc in the Elderly People by 出口, 昌孝, 上瀬, 英彦, 西田, 圭吾, 大井, 一弥

“…In recent years, it has become clear that zinc deficiency is closely related in several skin disorders. In elderly people, chronic itch and dry skin are…”
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