Search Results - "Nishi, Nozomu"

Sodium/glucose cotransporter 2 is expressed in choroid plexus epithelial cells and ependymal cells in human and mouse brains by Chiba, Yoichi, Sugiyama, Yasunori, Nishi, Nozomu, Nonaka, Wakako, Murakami, Ryuta, Ueno, Masaki

“…Diabetes mellitus (DM) is now recognized as one of the risk factors for Alzheimer's disease (AD), and the disease‐modifying effects of anti‐diabetic drugs on…”
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Chemoenzymatic Synthesis of the Immunoglobulin Domain of Tim-3 Carrying a Complex-Type N-Glycan by Using a One-pot Ligation by Asahina, Yuya, Kamitori, Shigehiro, Takao, Toshifumi, Nishi, Nozomu, Hojo, Hironobu

“…Ligations: The title immunoglobin (Ig) domain was chemoenzymatically synthesized. The domain was divided into three segments and N‐ and S‐protected peptide…”
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Galectin-9 induces atypical ubiquitination leading to cell death in PC-3 prostate cancer cells by Itoh, Aiko, Nonaka, Yasuhiro, Ogawa, Takashi, Nakamura, Takanori, Nishi, Nozomu

“…Galectin-9 is the most potent inducer of cell death in lymphomas and other malignant cell types among the members of the galectin family. We investigated the…”
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Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies by Madireddi, Shravan, Eun, So-Young, Lee, Seung-Woo, Nemčovičová, Ivana, Mehta, Amit Kumar, Zajonc, Dirk M, Nishi, Nozomu, Niki, Toshiro, Hirashima, Mitsuomi, Croft, Michael

“…Biologics to TNF family receptors are prime candidates for therapy of immune disease. Whereas recent studies have highlighted a requirement for Fcγ receptors…”
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Modulation of the carbohydrate-binding specificity of two Xenopus proto-type galectins by site-directed mutagenesis by Nonaka, Yasuhiro, Ogawa, Takashi, Shoji, Hiroki, Nishi, Nozomu, Kamitori, Shigehiro, Nakamura, Takanori

“…The galectin family is a representative soluble lectin group, which is responsible for the modulation of various cell functions. Although the…”
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Cell surface galectin-9 expressing Th cells regulate Th17 and Foxp3+ Treg development by galectin-9 secretion by Oomizu, Souichi, Arikawa, Tomohiro, Niki, Toshiro, Kadowaki, Takeshi, Ueno, Masaki, Nishi, Nozomu, Yamauchi, Akira, Hattori, Toshio, Masaki, Tsutomu, Hirashima, Mitsuomi

“…Galectin-9 (Gal-9), a β-galactoside binding mammalian lectin, regulates immune responses by reducing pro-inflammatory IL-17-producing Th cells (Th17) and…”
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Immunoreactivity of receptor and transporters for lactate located in astrocytes and epithelial cells of choroid plexus of human brain by Murakami, Ryuta, Chiba, Yoichi, Nishi, Nozomu, Matsumoto, Koichi, Wakamatsu, Keiji, Yanase, Ken, Uemura, Naoya, Nonaka, Wakako, Ueno, Masaki

“…•Transporters for lactate were immunohistochemically examined in human brains.•MCT1 and MCT4 were located in astrocytes and epithelial cells of choroid…”
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Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells by Dardalhon, Valerie, Anderson, Ana C, Karman, Jozsef, Apetoh, Lionel, Chandwaskar, Rucha, Lee, David H, Cornejo, Melanie, Nishi, Nozomu, Yamauchi, Akira, Quintana, Francisco J, Sobel, Raymond A, Hirashima, Mitsuomi, Kuchroo, Vijay K

“…IFN-gamma plays a central role in antitumor immunity. T cell Ig and mucin domain (Tim-3) is expressed on IFN-gamma-producing Th1 cells; on interaction with its…”
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Exosomes released by EBV-infected nasopharyngeal carcinoma cells convey the viral latent membrane protein 1 and the immunomodulatory protein galectin 9 by Keryer-Bibens, Cécile, Pioche-Durieu, Catherine, Villemant, Cécile, Souquère, Sylvie, Nishi, Nozomu, Hirashima, Mitsuomi, Middeldorp, Jaap, Busson, Pierre

“…Nasopharyngeal carcinomas (NPC) are consistently associated with the Epstein-Barr virus (EBV). Their malignant epithelial cells contain the viral genome and…”
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Galectin-9 Is a High Affinity IgE-binding Lectin with Anti-allergic Effect by Blocking IgE-Antigen Complex Formation by Niki, Toshiro, Tsutsui, Shoko, Hirose, Shigeru, Aradono, Sachiko, Sugimoto, Yasushi, Takeshita, Keisuke, Nishi, Nozomu, Hirashima, Mitsuomi

“…Galectin (Gal)-9 was first described as an eosinophil chemoattractant. With the progress in research, Gal-9 has come to be known as a versatile immunomodulator…”
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Small leucine-rich repeat proteoglycans associated with mature insoluble elastin serve as binding sites for galectins by Itoh, Aiko, Nonaka, Yasuhiro, Ogawa, Takashi, Nakamura, Takanori, Nishi, Nozomu

“…We previously reported that galectin-9 (Gal-9), an immunomodulatory animal lectin, could bind to insoluble collagen preparations and exerted direct cytocidal…”
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Oligosaccharide specificity of galectins: a search by frontal affinity chromatography by Hirabayashi, Jun, Hashidate, Tomomi, Arata, Yoichiro, Nishi, Nozomu, Nakamura, Takanori, Hirashima, Mitsuomi, Urashima, Tadasu, Oka, Toshihiko, Futai, Masamitsu, Muller, Werner E.G, Yagi, Fumio, Kasai, Ken-ichi

“…Galectins are widely distributed sugar-binding proteins whose basic specificity for β-galactosides is conserved by evolutionarily preserved…”
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Galectin-9 Inhibits CD44-Hyaluronan Interaction and Suppresses a Murine Model of Allergic Asthma by Katoh, Shigeki, Ishii, Naoki, Nobumoto, Atsuya, Takeshita, Keisuke, Dai, Shu-Yan, Shinonaga, Rika, Niki, Toshiro, Nishi, Nozomu, Tominaga, Akira, Yamauchi, Akira, Hirashima, Mitsuomi

“…Galectin-9 (Gal-9) belongs to the galectin family, which exhibits affinity for beta-galactosides. Gal-9 has a variety of biological activities; however, its…”
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Crystal structure of a Xenopus laevis skin proto-type galectin, close to but distinct from galectin-1 by Nonaka, Yasuhiro, Ogawa, Takashi, Yoshida, Hiromi, Shoji, Hiroki, Nishi, Nozomu, Kamitori, Shigehiro, Nakamura, Takanori

“…Xenopus laevis (African clawed frog) has two types of proto-type galectins that are similar to mammalian galectin-1 in amino acid sequence. One type,…”
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Acceleration of periosteal bone formation by human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase by Uchida, Kentaro, Matsushita, Osamu, Naruse, Kouji, Mima, Takehiko, Nishi, Nozomu, Hattori, Shunji, Ogura, Takayuki, Inoue, Gen, Tanaka, Keisuke, Takaso, Masashi

“…Basic fibroblast growth factor 2 (bFGF) is a potent mitogen for mesenchymal cells, and the local application of recombinant bFGF accelerates bone union and…”
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Galectin-9 Induces Apoptosis Through the Calcium-Calpain-Caspase-1 Pathway by Kashio, Yumiko, Nakamura, Kazuhiro, Abedin, Mohammad J, Seki, Masako, Nishi, Nozomu, Yoshida, Naoko, Nakamura, Takanori, Hirashima, Mitsuomi

“…Galectin-9 (Gal-9) induced the apoptosis of not only T cell lines but also of other types of cell lines in a dose- and time-dependent manner. The apoptosis was…”
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Galectin-9 as a Prognostic Factor with Antimetastatic Potential in Breast Cancer by IRIE, Akemi, YAMAUCHI, Akira, HIRASHIMA, Mitsuomi, KONTANI, Keiichi, KIHARA, Minoru, LIU, Dage, SHIRATO, Yukako, SEKI, Masako, NISHI, Nozomu, NAKAMURA, Takanori, YOKOMISE, Hiroyasu

“…Purpose: Galectin-9, a member of the β-galactoside–binding galectin family, induces aggregation of certain cell types. We assessed the contribution of…”
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Crystal Structure of the Galectin-9 N-terminal Carbohydrate Recognition Domain from Mus musculus Reveals the Basic Mechanism of Carbohydrate Recognition by Nagae, Masamichi, Nishi, Nozomu, Murata, Takeomi, Usui, Taichi, Nakamura, Takanori, Wakatsuki, Soichi, Kato, Ryuichi

“…The galectins are a family of β-galactoside-binding animal lectins with a conserved carbohydrate recognition domain (CRD). They have a high affinity for small…”
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Acceleration of bone formation during fracture healing by injectable collagen powder and human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase by Saito, Wataru, Uchida, Kentaro, Ueno, Masaki, Matsushita, Osamu, Inoue, Gen, Nishi, Nozomu, Ogura, Takayuki, Hattori, Shunji, Fujimaki, Hisako, Tanaka, Keisuke, Takaso, Masashi

“…Growth factor delivered with implantable biomaterials has been used to both accelerate and ensure healing of open fractures in human patients. However, a major…”
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The Glycan-Binding Protein Galectin-9 Has Direct Apoptotic Activity toward Melanoma Cells by Wiersma, Valerie R., de Bruyn, Marco, van Ginkel, Robert J., Sigar, Emily, Hirashima, Mitsuomi, Niki, Toshiro, Nishi, Nozomu, Samplonius, Douwe F., Helfrich, Wijnand, Bremer, Edwin

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