Search Results - "Nishanth, M. J."

Understanding the neural basis of survival instinct vs. suicidal behavior: a key to decode the biological enigma of human suicidal behavior by Nishanth, M. J., Jha, Shanker

“…Suicidal behavior is a globally widespread psychiatric disorder with a high rate of mortality. Suicide causes psychological and economic hardships for the…”
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Global Exploration of RNA-Binding Proteins in Exercise-Induced Adult Hippocampal Neurogenesis: A Transcriptome Meta-analysis and Computational Study by Nishanth, M. J., Jha, Shanker

“…Voluntary physical exercise is a robust enhancer of adult hippocampal neurogenesis (AHN). A complete understanding of the molecular regulation of AHN is…”
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Computational analysis of crosstalk between transcriptional regulators and RNA-binding proteins suggests mutual regulation of polycomb proteins and SRSF1 influencing adult hippocampal neurogenesis by Nishanth, M. J., Jha, Shanker

“…Background Adult hippocampal neurogenesis (AHN) is a clinically significant neural phenomenon. Understanding its molecular regulation would be important. In…”
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Genome-wide landscape of RNA-binding protein networks as potential molecular regulators of psychiatric co-morbidities: a computational analysis by Nishanth, M. J, Jha, Shanker

“…Background Psychiatric disorders are a major burden on global health. These illnesses manifest as co-morbid conditions, further complicating the treatment…”
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Computational analysis of the divergent neurotranscriptomic signatures of major depression and suicidality by Nishanth, M. J, Karthick, S. Sai, Jha, Shanker

“…Background Suicide is a leading cause of death globally. Identifying individuals at higher suicidal risk is a key to suicide prevention. Patients with comorbid…”
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Stress-Mediated cis -Element Transcription Factor Interactions Interconnecting Primary and Specialized Metabolism in planta by Sheshadri, S A, Nishanth, M J, Simon, Bindu

“…Plant specialized metabolites are being used worldwide as therapeutic agents against several diseases. Since the precursors for specialized metabolites come…”
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Expression analysis of Cell wall invertase under abiotic stress conditions influencing specialized metabolism in Catharanthus roseus by Nishanth, M. J., Sheshadri, S. A., Rathore, Sudarshan Singh, Srinidhi, S., Simon, Bindu

“…Catharanthus roseus is a commercial source for anti-cancer terpenoid indole alkaloids (TIAs: vincristine and vinblastine). Inherent levels of these TIAs are…”
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Transcriptome meta-analysis-based identification of hub transcription factors and RNA-binding proteins potentially orchestrating gene regulatory cascades and crosstalk in response to abiotic stresses in Arabidopsis thaliana by Nishanth, M. J.

“…Deteriorating climatic conditions and increasing human population necessitate the development of robust plant varieties resistant to harsh environments…”
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Functions, mechanisms and regulation of Pumilio/Puf family RNA binding proteins: a comprehensive review by Nishanth, M. J., Simon, Bindu

“…The Pumilio (Pum)/Puf family proteins are ubiquitously present across eukaryotes, including yeast, plants and humans. They generally bind to the 3′…”
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Evolutionary Analysis of the hnRNP Interactomes and Their Functions in Eukaryotes by Nishanth, M. J., Jha, Shanker

“…The heterogeneous nuclear ribonucleoproteins (hnRNPs) are central regulators of several fundamental biological processes across eukaryotes. hnRNPs have been…”
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Melatonin Influences Terpenoid Indole Alkaloids Biosynthesis and 5′ Upstream-Mediated Regulation of Cell wall Invertase in Catharanthus roseus by Sheshadri, S. A., Nishanth, M. J., Simon, Bindu

“…Melatonin is a well-known hormone, found ubiquitously in plants and has been known to impart several beneficial traits. Although its role in influencing…”
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Understanding the possible influence of Pumilio RNA binding proteins on terpenoid indole alkaloid biosynthesis in Catharanthus roseus by Nishanth, M. J., Simon, Bindu

“…Catharanthus roseus is a clinically significant medicinal plant; the sole source of chemotherapy agents, vincristine and vinblastine (specialized metabolites,…”
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Effect of Melatonin on the stability and expression of reference genes in Catharanthus roseus by Sheshadri, S. A., Nishanth, M. J., Yamine, V., Simon, Bindu

“…The role of Melatonin in influencing diverse genes in plants has gained momentum in recent years and many reports have employed qRT-PCR for their…”
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Comparative genome based cis-elements analysis in the 5′ upstream and 3′ downstream region of cell wall invertase and Phenylalanine ammonia lyase in Nicotiana benthamiana by Sheshadri, S.A., Nishanth, M.J., Harita, N., Brindha, P., Bindu, S.

“…[Display omitted] •Cis-elements of CWIN and PAL may co-regulate primary and secondary metabolisms in Nicotiana benthamiana.•Stress-responsive cis-elements of…”
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