Search Results - "Nisha, Nair"
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Impact of Staphylococcus aureus on pathogenesis in polymicrobial infections
Published in Infection and immunity (01-06-2014)“…Polymicrobial infections involving Staphylococcus aureus exhibit enhanced disease severity and morbidity. We reviewed the nature of polymicrobial interactions…”
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Predicting treatment response to IL6R blockers in rheumatoid arthritis
Published in Rheumatology (Oxford, England) (01-12-2020)“…Abstract Patients with severe, active RA who have not responded to conventional therapy may receive biological disease modifying anti-rheumatic drugs…”
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Therapeutic opportunities of edible antiviral plants for COVID-19
Published in Molecular and cellular biochemistry (01-06-2021)“…The pandemic of Serious Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2) that produces corona virus disease (COVID-19) has challenged the entire mankind…”
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The route of infection with Leptospira interrogans serovar Copenhageni affects the kinetics of bacterial dissemination and kidney colonization
Published in PLoS neglected tropical diseases (01-01-2020)“…The goal of this study was to characterize how natural routes of infection affect the kinetics of pathogenic Leptospira dissemination to blood and kidney…”
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Sleep duration and mortality among breast cancer survivors in the Western New York Exposures and Breast Cancer (WEB) Study
Published in Cancer causes & control (2024)“…Purpose There is increasing evidence that sleep duration may affect breast cancer survival through effects on circadian function, influencing disease…”
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Adjuvant Trastuzumab in HER2-Positive Early Breast Cancer by Age and Hormone Receptor Status: A Cost-Utility Analysis
Published in PLoS medicine (09-08-2016)“…The anti-human epidermal growth factor receptor 2 (HER2) monoclonal antibody trastuzumab improves outcomes in patients with node-positive HER2+ early breast…”
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Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells
Published in Nucleic acids research (19-09-2018)“…Abstract CRISPR/Cas9 is an attractive platform to potentially correct dominant genetic diseases by gene editing with unprecedented precision. In the current…”
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Prediction of response of methotrexate in patients with rheumatoid arthritis using serum lipidomics
Published in Scientific reports (31-03-2021)“…Methotrexate (MTX) is a common first-line treatment for new-onset rheumatoid arthritis (RA). However, MTX is ineffective for 30–40% of patients and there is no…”
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Fatal Multisystem Inflammatory Syndrome in Adult after SARS-CoV-2 Natural Infection and COVID-19 Vaccination
Published in Emerging infectious diseases (01-11-2021)“…We describe a fatal case of multisystem inflammatory syndrome in an adult with onset 22 days after a second dose of mRNA coronavirus disease vaccine. Serologic…”
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Home modification to reduce falls at a health district level : modeling health gain, health inequalities and health costs
Published in PloS one (14-09-2017)“…Investigates the cost-effectiveness and impact in terms of health gain at a health-district level of a home safety assessment and modification (HSAM) programme…”
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Transcriptome-wide study of TNF-inhibitor therapy in rheumatoid arthritis reveals early signature of successful treatment
Published in Arthritis research & therapy (10-03-2021)“…Despite the success of TNF-inhibitor therapy in rheumatoid arthritis treatment, up to 40% of patients fail to respond adequately. This study aimed to identify…”
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Computationally designed liver-specific transcriptional modules and hyperactive factor IX improve hepatic gene therapy
Published in Blood (15-05-2014)“…The development of the next-generation gene therapy vectors for hemophilia requires using lower and thus potentially safer vector doses and augmenting their…”
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Culture and COVID-19: Impact of Cross-Cultural Dimensions on Behavioral Responses
Published in Encyclopedia (Basel, Switzerland) (01-07-2022)“…The global pandemic of COVID-19 has impacted every sphere of human life across all nations of the world. Countries adapted and responded to the crisis in…”
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Deconvolution of whole blood transcriptomics identifies changes in immune cell composition in patients with systemic lupus erythematosus (SLE) treated with mycophenolate mofetil
Published in Arthritis research & therapy (30-06-2023)“…Systemic lupus erythematosus (SLE) is a clinically and biologically heterogeneous autoimmune disease. We explored whether the deconvolution of whole blood…”
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Role of TLR4 in Persistent Leptospira interrogans Infection: A Comparative In Vivo Study in Mice
Published in Frontiers in immunology (15-01-2021)“…Toll-Like Receptor (TLR) 4, the LPS receptor, plays a central role in the control of leptospirosis and absence of TLR4 results in lethal infection in mice…”
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Correction to: Transcriptome-wide study of TNF-inhibitor therapy in rheumatoid arthritis reveals early signature of successful treatment
Published in Arthritis research & therapy (08-05-2021)“…Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing,…”
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A screening program to test and treat for Helicobacter pylori infection: Cost-utility analysis by age, sex and ethnicity
Published in BMC infectious diseases (20-02-2017)“…The World Health Organization recommends all countries consider screening for H. pylori to prevent gastric cancer. We therefore aimed to estimate the…”
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Cancer Care Coordinators to Improve Tamoxifen Persistence in Breast Cancer: How Heterogeneity in Baseline Prognosis Impacts on Cost-Effectiveness
Published in Value in health (01-12-2016)“…Abstract Objectives To assess the cost-effectiveness of a cancer care coordinator (CCC) in helping women with estrogen receptor positive (ER+) early breast…”
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Intranasal vaccine for Lyme disease provides protection against tick transmitted Borrelia burgdorferi beyond one year
Published in npj vaccines (15-02-2024)“…Strategies for disease control are necessary to reduce incidence of Lyme Disease (LD) including development of safe vaccines for human use. Parainfluenza virus…”
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