Search Results - "Nirujogi, Raja Sekhar"

Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling by Ugolino, Janet, Ji, Yon Ju, Conchina, Karen, Chu, Justin, Nirujogi, Raja Sekhar, Pandey, Akhilesh, Brady, Nathan R, Hamacher-Brady, Anne, Wang, Jiou

“…The most common cause of the neurodegenerative diseases amyotrophic lateral sclerosis and frontotemporal dementia is a hexanucleotide repeat expansion in…”
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Ubiquilin 2 modulates ALS/FTD-linked FUS–RNA complex dynamics and stress granule formation by Alexander, Elizabeth J., Niaki, Amirhossein Ghanbari, Zhang, Tao, Sarkar, Jaya, Liu, Yang, Nirujogi, Raja Sekhar, Pandey, Akhilesh, Myong, Sua, Wang, Jiou

“…The ubiquitin-like protein ubiquilin 2 (UBQLN2) has been genetically and pathologically linked to the neurodegenerative diseases amyotrophic lateral sclerosis…”
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Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies by Armstrong, Lee A, Lange, Sven M, Dee Cesare, Virginia, Matthews, Stephen P, Nirujogi, Raja Sekhar, Cole, Isobel, Hope, Anthony, Cunningham, Fraser, Toth, Rachel, Mukherjee, Rukmini, Bojkova, Denisa, Gruber, Franz, Gray, David, Wyatt, Paul G, Cinatl, Jindrich, Dikic, Ivan, Davies, Paul, Kulathu, Yogesh

“…Of the 16 non-structural proteins (Nsps) encoded by SARS CoV-2, Nsp3 is the largest and plays important roles in the viral life cycle. Being a large,…”
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Proteomic Analysis of Plasmodium Merosomes: The Link between Liver and Blood Stages in Malaria by Shears, Melanie J, Sekhar Nirujogi, Raja, Swearingen, Kristian E, Renuse, Santosh, Mishra, Satish, Jaipal Reddy, Panga, Moritz, Robert L, Pandey, Akhilesh, Sinnis, Photini

“…The pre-erythrocytic liver stage of the malaria parasite, comprising sporozoites and the liver stages into which they develop, remains one of the least…”
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Proteomic analysis of human follicular fluid: A new perspective towards understanding folliculogenesis by Ambekar, Aditi S., Nirujogi, Raja Sekhar, Srikanth, Srinivas M., Chavan, Sandip, Kelkar, Dhanashree S., Hinduja, Indira, Zaveri, Kusum, Prasad, T.S. Keshava, Harsha, H.C., Pandey, Akhilesh, Mukherjee, Srabani

“…Human follicular fluid is a complex body fluid that constitutes the microenvironment of developing follicles in the ovary. Follicular fluid contains a number…”
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Phosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic Signaling by Li, Renfeng, Liao, Gangling, Nirujogi, Raja Sekhar, Pinto, Sneha M, Shaw, Patrick G, Huang, Tai-Chung, Wan, Jun, Qian, Jiang, Gowda, Harsha, Wu, Xinyan, Lv, Dong-Wen, Zhang, Kun, Manda, Srikanth S, Pandey, Akhilesh, Hayward, S Diane

“…Epstein-Barr virus (EBV) is etiologically linked to infectious mononucleosis and several human cancers. EBV encodes a conserved protein kinase BGLF4 that plays…”
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Integrated Transcriptomic and Proteomic Analysis of Primary Human Umbilical Vein Endothelial Cells by Madugundu, Anil K., Na, Chan Hyun, Nirujogi, Raja Sekhar, Renuse, Santosh, Kim, Kwang Pyo, Burns, Kathleen H., Wilks, Christopher, Langmead, Ben, Ellis, Shannon E., Collado‐Torres, Leonardo, Halushka, Marc K., Kim, Min‐Sik, Pandey, Akhilesh

“…Understanding the molecular profile of every human cell type is essential for understanding its role in normal physiology and disease. Technological…”
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Proteomic analysis of human osteoarthritis synovial fluid by Balakrishnan, Lavanya, Nirujogi, Raja Sekhar, Ahmad, Sartaj, Bhattacharjee, Mitali, Manda, Srikanth S, Renuse, Santosh, Kelkar, Dhanashree S, Subbannayya, Yashwanth, Raju, Rajesh, Goel, Renu, Thomas, Joji Kurian, Kaur, Navjyot, Dhillon, Mukesh, Tankala, Shantal Gupta, Jois, Ramesh, Vasdev, Vivek, Ramachandra, Yl, Sahasrabuddhe, Nandini A, Prasad, Ts Keshava, Mohan, Sujatha, Gowda, Harsha, Shankar, Subramanian, Pandey, Akhilesh

“…Osteoarthritis is a chronic musculoskeletal disorder characterized mainly by progressive degradation of the hyaline cartilage. Patients with osteoarthritis…”
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Differential proteomic analysis of synovial fluid from rheumatoid arthritis and osteoarthritis patients by Balakrishnan, Lavanya, Bhattacharjee, Mitali, Ahmad, Sartaj, Nirujogi, Raja Sekhar, Renuse, Santosh, Subbannayya, Yashwanth, Marimuthu, Arivusudar, Srikanth, Srinivas M, Raju, Rajesh, Dhillon, Mukesh, Kaur, Navjyot, Jois, Ramesh, Vasudev, Vivek, Ramachandra, Yl, Sahasrabuddhe, Nandini A, Prasad, Ts Keshava, Mohan, Sujatha, Gowda, Harsha, Shankar, Subramanian, Pandey, Akhilesh

“…Rheumatoid arthritis and osteoarthritis are two common musculoskeletal disorders that affect the joints. Despite high prevalence rates, etiological factors…”
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A proteogenomic approach to map the proteome of an unsequenced pathogen - Leishmania donovani by Pawar, Harsh, Sahasrabuddhe, Nandini A., Renuse, Santosh, Keerthikumar, Shivakumar, Sharma, Jyoti, Kumar, Ghantasala. S. Sameer, Venugopal, Abhilash, Sekhar, Nirujogi Raja, Kelkar, Dhanashree S., Nemade, Harshal, Khobragade, Sweta N., Muthusamy, Babylakshmi, Kandasamy, Kumaran, Harsha, H. C., Chaerkady, Raghothama, Patole, Milind S., Pandey, Akhilesh

“…Visceral leishmaniasis or kala azar is the most severe form of leishmaniasis and is caused by the protozoan parasite Leishmania donovani. There is no published…”
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Phosphoproteomic profiling of tumor tissues identifies HSP27 Ser82 phosphorylation as a robust marker of early ischemia by Zahari, Muhammad Saddiq, Wu, Xinyan, Pinto, Sneha M., Nirujogi, Raja Sekhar, Kim, Min-Sik, Fetics, Barry, Philip, Mathew, Barnes, Sheri R., Godfrey, Beverly, Gabrielson, Edward, Nevo, Erez, Pandey, Akhilesh

“…Delays between tissue collection and tissue fixation result in ischemia and ischemia-associated changes in protein phosphorylation levels, which can misguide…”
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A proteogenomic analysis of Anopheles gambiae using high-resolution Fourier transform mass spectrometry by Chaerkady, Raghothama, Kelkar, Dhanashree S, Muthusamy, Babylakshmi, Kandasamy, Kumaran, Dwivedi, Sutopa B, Sahasrabuddhe, Nandini A, Kim, Min-Sik, Renuse, Santosh, Pinto, Sneha M, Sharma, Rakesh, Pawar, Harsh, Sekhar, Nirujogi Raja, Mohanty, Ajeet Kumar, Getnet, Derese, Yang, Yi, Zhong, Jun, Dash, Aditya P, MacCallum, Robert M, Delanghe, Bernard, Mlambo, Godfree, Kumar, Ashwani, Keshava Prasad, T S, Okulate, Mobolaji, Kumar, Nirbhay, Pandey, Akhilesh

“…Anopheles gambiae is a major mosquito vector responsible for malaria transmission, whose genome sequence was reported in 2002. Genome annotation is a…”
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Proteomic analysis of purified protein derivative of Mycobacterium tuberculosis by Prasad, Thottethodi Subrahmanya Keshava, Verma, Renu, Kumar, Satish, Nirujogi, Raja Sekhar, Sathe, Gajanan J, Madugundu, Anil K, Sharma, Jyoti, Puttamallesh, Vinuth N, Ganjiwale, Anjali, Myneedu, Vithal P, Chatterjee, Aditi, Pandey, Akhilesh, Harsha, Hc, Narayana, Jayasuryan

“…Purified protein derivative (PPD) has been used for more than half a century as an antigen for the diagnosis of tuberculosis infection based on delayed type…”
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A multilectin affinity approach for comparative glycoprotein profiling of rheumatoid arthritis and spondyloarthropathy by Bhattacharjee, Mitali, Sharma, Rakesh, Goel, Renu, Balakrishnan, Lavanya, Renuse, Santosh, Advani, Jayshree, Gupta, Shantal Tankala, Verma, Renu, Pinto, Sneha M, Sekhar, Nirujogi Raja, Nair, Bipin, Prasad, T S Keshava, Harsha, H C, Jois, Ramesh, Shankar, Subramanian, Pandey, Akhilesh

“…Arthritis refers to inflammation of joints and includes common disorders such as rheumatoid arthritis (RA) and spondyloarthropathies (SpAs). These diseases…”
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Identification of targets of miR-200b by a SILAC-based quantitative proteomic approach by Marimuthu, Arivusudar, Huang, Tai-Chung, Selvan, Lakshmi Dhevi N., Renuse, Santosh, Nirujogi, Raja Sekhar, Kumar, Praveen, Pinto, Sneha M., Rajagopalan, Sudha, Pandey, Akhilesh, Harsha, H.C., Chatterjee, Aditi

“…•Demonstrates SILAC coupled robust mass spectrometry-based approach to identify protein targets regulated by miRNAs.•Reports identification and quantification…”
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Identification of long-lived synaptic proteins by proteomic analysis of synaptosome protein turnover by Heo, Seok, Diering, Graham H., Na, Chan Hyun, Nirujogi, Raja Sekhar, Bachman, Julia L., Pandey, Akhilesh, Huganir, Richard L.

“…Memory formation is believed to result from changes in synapse strength and structure. While memories may persist for the lifetime of an organism, the proteins…”
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Quantitative Proteomics Reveals that the OGT Interactome Is Remodeled in Response to Oxidative Stress by Martinez, Marissa, Renuse, Santosh, Kreimer, Simion, O’Meally, Robert, Natov, Peter, Madugundu, Anil K., Nirujogi, Raja Sekhar, Tahir, Raiha, Cole, Robert, Pandey, Akhilesh, Zachara, Natasha E.

“…The dynamic modification of specific serine and threonine residues of intracellular proteins by O-linked N-acetyl-β-D-glucosamine (O-GlcNAc) mitigates injury…”
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Complement and Coagulation Cascades are Potentially Involved in Dopaminergic Neurodegeneration in α‑Synuclein-Based Mouse Models of Parkinson’s Disease by Ma, Shi-Xun, Seo, Bo Am, Kim, Donghoon, Xiong, Yulan, Kwon, Seung-Hwan, Brahmachari, Saurav, Kim, Sangjune, Kam, Tae-In, Nirujogi, Raja Sekhar, Kwon, Sang Ho, Dawson, Valina L, Dawson, Ted M, Pandey, Akhilesh, Na, Chan Hyun, Ko, Han Seok

“…Parkinson’s disease (PD) is the second most common neurodegenerative disorder that results in motor dysfunction and, eventually, cognitive impairment…”
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Correction: Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies by Armstrong, Lee A, Lange, Sven M, Cesare, Virginia De, Matthews, Stephen P, Nirujogi, Raja Sekhar, Cole, Isobel, Hope, Anthony, Cunningham, Fraser, Toth, Rachel, Mukherjee, Rukmini, Bojkova, Denisa, Gruber, Franz, Gray, David, Wyatt, Paul G, Cinatl, Jindrich, Dikic, Ivan, Davies, Paul, Kulathu, Yogesh

“…[This corrects the article DOI: 10.1371/journal.pone.0253364.]…”
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Mutation-Specific and Common Phosphotyrosine Signatures of KRAS G12D and G13D Alleles by Tahir, Raiha, Renuse, Santosh, Udainiya, Savita, Madugundu, Anil K, Cutler, Jevon A, Nirujogi, Raja Sekhar, Na, Chan Hyun, Xu, Yaoyu, Wu, Xinyan, Pandey, Akhilesh

“…KRAS is one of the most frequently mutated genes across all cancer subtypes. Two of the most frequent oncogenic KRAS mutations observed in patients result in…”
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