Search Results - "Nirmala, N.R."

P764 ANALYSIS OF THE EFFECT OF CYCLOPHILIN INHIBITOR ALISPORIVIR ON THE INTERFERON RESPONSE IN HCV-INFECTED CELLS AND PATIENTS by Bobardt, M, Baugh, J, Gallay, P, Ma, S, Kaiser, S, Hartmann, N, Letzkus, M, Staedtler, F, Riva, A, Chokshi, S, Nirmala, N.R, Johnson, K.J, Brass, C.A, Naoumov, N.V, Li, B

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Identification of novel pathway regulation during myogenic differentiation by Szustakowski, Joseph D., Lee, Jee-Hyung, Marrese, Christine A., Kosinski, Penelope A., Nirmala, N.R., Kemp, Daniel M.

“…Stem cell differentiation is governed by extracellular signals that activate intracellular networks (or pathways) to drive phenotypic specification. Using a…”
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Whole‐Exome Sequencing Reveals Overlap Between Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis and Familial Hemophagocytic Lymphohistiocytosis by Kaufman, Kenneth M., Linghu, Bolan, Szustakowski, Joseph D., Husami, Ammar, Yang, Fan, Zhang, Kejian, Filipovich, Alexandra H., Fall, Ndate, Harley, John B., Nirmala, N. R., Grom, Alexei A.

“…Objective Macrophage activation syndrome (MAS), a life‐threatening complication of systemic juvenile idiopathic arthritis (JIA), resembles familial…”
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Estrogen-related receptor α is essential for the expression of antioxidant protection genes and mitochondrial function by Rangwala, Shamina M., Li, Xiaoyan, Lindsley, Loren, Wang, Xiaomei, Shaughnessy, Stacey, Daniels, Thomas G., Szustakowski, Joseph, Nirmala, N.R., Wu, Zhidan, Stevenson, Susan C.

“…Estrogen-related receptor α (ERRα) is an important mediator of mitochondrial biogenesis and function. To investigate the transcriptional network controlling…”
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Estrogen-related receptor {alpha} is essential for the expression of antioxidant protection genes and mitochondrial function by Rangwala, Shamina M., Li, Xiaoyan, Lindsley, Loren, Wang, Xiaomei, Shaughnessy, Stacey, Daniels, Thomas G., Szustakowski, Joseph, Nirmala, N.R., Wu, Zhidan, Stevenson, Susan C.

“…Estrogen-related receptor {alpha} (ERR{alpha}) is an important mediator of mitochondrial biogenesis and function. To investigate the transcriptional network…”
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Genomic Data Mining and Its Impact on Drug Discovery by Nirmala, N.R.

“…This chapter presents an analysis of gene expression profiling data and discusses the use of computational biology and comparative genomics in the area of the…”
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Measurement of sup 13 C relaxation times in proteins by two-dimensional heteronuclear sup 1 H- sup 13 C correlation spectroscopy by Nirmala, N.R., Wagner, G.

“…A heteropolar 2D NMR technique for measurement of {sub 13}C T{sub 1} values in proteins previously reported has been applied to the determination of…”
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On-resin macrocyclization of peptides via intramolecular SNAr reactions by FOTSCH, C, KUMARAVEL, G, SHARMA, S. K, WU, A. D, GOUNARIDES, J. S, NIRMALA, N. R, PETTER, R. C

“…On-resin macrocyclization via an SNAr reaction is employed in the synthesis of tocinoic acid analogs. Specifically, an N-terminal nitrofluorobenzene is…”
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On-resin macrocyclization of peptides via intramolecular S nAr reactions by Fotsch, Christopher, Kumaravel, G., Sharma, Sushil K., Wu, Arthur D., Gounarides, John S., Nirmala, N.R., Petter, Russell C.

“…On-resin macrocyclization via an S nAr reaction is employed in the synthesis of tocinoic acid analogs. Specifically, an N-terminal nitrofluorobenzene is…”
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Sequence-specific sup 1 H and sup 15 N resonance assignments for human dihydrofolate reductase in solution by Stockman, B.J., Nirmala, N.R., Wagner, G., Delcamp, T.J., DeYarman, M.T., Freisheim, J.H.

“…Dihydrofolate reductase is an intracellular target enzyme for folate antagonists, including the anticancer drug methotrexate. In order to design novel drugs…”
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Methotrexate binds in a non-productive orientation to human dihydrofolate reductase in solution, based on NMR spectroscopy by Stockman, Brian J., Nirmala, N.R., Wagner, Gerhard, Delcamp, Tavner J., DeYarman, Michael T., Freisheim, James H.

“…Dihydrofolate reductase (DHFR) is an intracellular target enzyme for folate antagonist drugs, including methotrexatte. In order to compare the binding of…”
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