Search Results - "Nirit Mor-Vaknin"

Anti-vimentin antibodies: a unique antibody class associated with therapy-resistant lupus nephritis by Kinloch, Andrew J, Cascino, Matthew D, Dai, Jian, Bermea, Rene S, Ko, Kichul, Vesselits, Margaret, Dragone, Leonard L, Mor Vaknin, Nirit, Legendre, Maureen, Markovitz, David M, Okoreeh, Michael K, Townsend, Michael J, Clark, Marcus R

“…Background Tubulointerstitial inflammation (TII) in lupus nephritis is associated with a worse prognosis. Vimentin, a filamental antigen, is commonly targeted…”
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High Levels of DEK Autoantibodies in Sera of Patients With Polyarticular Juvenile Idiopathic Arthritis and With Early Disease Flares Following Cessation of Anti–Tumor Necrosis Factor Therapy by Mor‐Vaknin, Nirit, Rivas, Miguel, Legendre, Maureen, Mohan, Smriti, Yuanfan, Ye, Mau, Theresa, Johnson, Anne, Huang, Bin, Zhao, Lili, Kimura, Yukiko, Spalding, Steven J., Morris, Paula W., Gottlieb, Beth S., Onel, Karen, Olson, Judyann C., Edelheit, Barbara S., Shishov, Michael, Jung, Lawrence K., Cassidy, Elaine A., Prahalad, Sampath, Passo, Murray H., Beukelman, Timothy, Mehta, Jay, Giannini, Edward H., Adams, Barbara S., Lovell, Daniel J., Markovitz, David M.

“…Objective The nuclear oncoprotein DEK is an autoantigen associated with juvenile idiopathic arthritis (JIA), especially the oligoarticular subtype. DEK is a…”
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Concise Review: Role of DEK in Stem/Progenitor Cell Biology by Broxmeyer, Hal E., Mor‐Vaknin, Nirit, Kappes, Ferdinand, Legendre, Maureen, Saha, Anjan K., Ou, Xuan, O'Leary, Heather, Capitano, Maegan, Cooper, Scott, Markovitz, David M.

“…Understanding the factors that regulate hematopoiesis opens up the possibility of modifying these factors and their actions for clinical benefit. DEK, a…”
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DEK, a nuclear protein, is chemotactic for hematopoietic stem/progenitor cells acting through CXCR2 and Gαi signaling by Capitano, Maegan L., Sammour, Yasser, Ropa, James, Legendre, Maureen, Mor‐Vaknin, Nirit, Markovitz, David M.

“…Few cytokines/growth modulating proteins are known to be chemoattractants for hematopoietic stem (HSC) and progenitor cells (HPC); stromal cell‐derived factor…”
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Citrullinated Histone H3 as a Therapeutic Target for Endotoxic Shock in Mice by Deng, Qiufang, Pan, Baihong, Alam, Hasan B, Liang, Yingjian, Wu, Zhenyu, Liu, Baoling, Mor-Vaknin, Nirit, Duan, Xiuzhen, Williams, Aaron M, Tian, Yuzi, Zhang, Justin, Li, Yongqing

“…Sepsis results in millions of deaths every year, with acute lung injury (ALI) being one of the leading causes of mortality in septic patients. As neutrophil…”
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DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis by Mor-Vaknin, Nirit, Saha, Anjan, Legendre, Maureen, Carmona-Rivera, Carmelo, Amin, M Asif, Rabquer, Bradley J., Gonzales-Hernandez, Marta J., Jorns, Julie, Mohan, Smriti, Yalavarthi, Srilakshmi, Pai, Dave A., Angevine, Kristine, Almburg, Shelley J., Knight, Jason S., Adams, Barbara S., Koch, Alisa E., Fox, David A., Engelke, David R., Kaplan, Mariana J., Markovitz, David M.

“…Novel therapeutics are required for improving the management of chronic inflammatory diseases. Aptamers are single-stranded RNA or DNA molecules that have…”
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Vimentin, a Novel NF-κB Regulator, Is Required for Meningitic Escherichia coli K1-Induced Pathogen Invasion and PMN Transmigration across the Blood-Brain Barrier by Huang, Sheng-He, Chi, Feng, Peng, Liang, Bo, Tao, Zhang, Bao, Liu, Li-Qun, Wu, Xuedong, Mor-Vaknin, Nirit, Markovitz, David M, Cao, Hong, Zhou, Yan-Hong

“…NF-κB activation, pathogen invasion, polymorphonuclear leukocytes (PMN) transmigration (PMNT) across the blood-brain barrier (BBB) are the pathogenic triad…”
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Vimentin is secreted by activated macrophages by Markovitz, David M, Mor-Vaknin, Nirit, Punturieri, Antonello, Sitwala, Kajal

“…Vimentin is a widely expressed intermediate filament protein thought to be involved mainly in structural processes, such as wound healing. We now demonstrate…”
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Intercellular trafficking of the nuclear oncoprotein DEK by Saha, Anjan K., Kappes, Ferdinand, Mundade, Amruta, Deutzmann, Anja, Rosmarin, David M., Legendre, Maureen, Chatain, Nicolas, Al-Obaidi, Zeina, Adams, Barbara S., Ploegh, Hidde L., Ferrando-May, Elisa, Mor-Vaknin, Nirit, Markovitz, David M.

“…DEK is a biochemically distinct, conserved nonhistone protein that is vital to global heterochromatin integrity. In addition, DEK can be secreted and function…”
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DEK in the synovium of patients with juvenile idiopathic arthritis: Characterization of DEK antibodies and posttranslational modification of the DEK autoantigen by Mor‐Vaknin, Nirit, Kappes, Ferdinand, Dick, Amalie E., Legendre, Maureen, Damoc, Catalina, Teitz‐Tennenbaum, Seagal, Kwok, Roland, Ferrando‐May, Elisa, Adams, Barbara S., Markovitz, David M.

“…Objective DEK is a nuclear phosphoprotein and autoantigen in a subset of children with juvenile idiopathic arthritis (JIA). Autoantibodies to DEK are also…”
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Intermediate filaments enable pathogen docking to trigger type 3 effector translocation by Russo, Brian C., Stamm, Luisa M., Raaben, Matthijs, Kim, Caleb M., Kahoud, Emily, Robinson, Lindsey R., Bose, Sayantan, Queiroz, Ana L., Herrera, Bobby Brooke, Baxt, Leigh A., Mor-Vaknin, Nirit, Fu, Yang, Molina, Gabriel, Markovitz, David M., Whelan, Sean P., Goldberg, Marcia B.

“…Type 3 secretion systems (T3SSs) of bacterial pathogens translocate bacterial effector proteins that mediate disease into the eukaryotic cytosol. Effectors…”
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Leukocytic promotion of prostate cellular proliferation by McDowell, Kristy L., Begley, Lesa A., Mor-Vaknin, Nirit, Markovitz, David M., Macoska, Jill A.

“…BACKGROUND Histological evidence of pervasive inflammatory infiltrate has been noted in both benign prostatic hyperplasia/hypertrophy (BPH) and prostate cancer…”
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The DEK Nuclear Autoantigen Is a Secreted Chemotactic Factor by Mor-Vaknin, Nirit, Punturieri, Antonello, Sitwala, Kajal, Faulkner, Neil, Legendre, Maureen, Khodadoust, Michael S., Kappes, Ferdinand, Ruth, Jeffrey H., Koch, Alisa, Glass, David, Petruzzelli, Lilli, Adams, Barbara S., Markovitz, David M.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Endothelial Cell-Specific Antibody PAL-E Identifies a Secreted Form of Vimentin in the Blood Vasculature by Xu, Bin, deWaal, Robert M., Mor-Vaknin, Nirit, Hibbard, Chris, Markovitz, David M., Kahn, Mark L.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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p300/CBP-associated Factor Drives DEK into Interchromatin Granule Clusters by Cleary, Joanne, Sitwala, Kajal V., Khodadoust, Michael S., Kwok, Roland P.S., Mor-Vaknin, Nirit, Cebrat, Marek, Cole, Philip A., Markovitz, David M.

“…DEK is a mammalian protein that has been implicated in the pathogenesis of autoimmune diseases and cancer, including acute myeloid leukemia, melanoma,…”
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Effect of dietary fat on early morphological intestinal adaptation in a rat with short bowel syndrome by Sukhotnik, Igor, Mor-Vaknin, Nirit, Drongowski, Robert A, Miselevich, Ines, Coran, Arnold G, Harmon, Carroll M

“…Among factors promoting mucosal hyperplasia after bowel resection, long-chain fatty acids may have a special role. The purpose of the present study was to…”
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The Tumor Inhibitor and Antiangiogenic Agent Withaferin A Targets the Intermediate Filament Protein Vimentin by Bargagna-Mohan, Paola, Hamza, Adel, Kim, Yang-eon, Khuan (Abby) Ho, Yik, Mor-Vaknin, Nirit, Wendschlag, Nicole, Liu, Junjun, Evans, Robert M., Markovitz, David M., Zhan, Chang-Guo, Kim, Kyung Bo, Mohan, Royce

“…The natural product withaferin A (WFA) exhibits antitumor and antiangiogenesis activity in vivo, which results from this drug's potent growth inhibitory…”
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Invasion of the Brain by Listeria monocytogenes Is Mediated by InlF and Host Cell Vimentin by Ghosh, Pallab, Halvorsen, Elizabeth M, Ammendolia, Dustin A, Mor-Vaknin, Nirit, O'Riordan, Mary X D, Brumell, John H, Markovitz, David M, Higgins, Darren E

“…is a facultative intracellular bacterial pathogen that is frequently associated with food-borne infection. Of particular concern is the ability of to breach…”
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Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling by Capitano, Maegan L, Mor-Vaknin, Nirit, Saha, Anjan K, Cooper, Scott, Legendre, Maureen, Guo, Haihong, Contreras-Galindo, Rafael, Kappes, Ferdinand, Sartor, Maureen A, Lee, Christopher T, Huang, Xinxin, Markovitz, David M, Broxmeyer, Hal E

“…The nuclear protein DEK is an endogenous DNA-binding chromatin factor regulating hematopoiesis. DEK is one of only 2 known secreted nuclear chromatin factors,…”
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Extracellular DEK Regulates Hematopoiesis through CXCR2-Mediated Intracellular Signaling That Does Not Require Its Translocation into the Nucleus or Binding to DNA by Capitano, Maegan, Mor-Vaknin, Nirit, Legendre, Maureen, Cooper, Scott, Kappes, Ferdinand, Markovitz, David, Broxmeyer, Hal E.

“…DEK is a highly conserved, ubiquitously expressed and structurally unique DNA-binding nuclear protein involved in transcription, DNA replication, and DNA…”
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