Search Results - "Nirala, Niraj K."

Ingestion of Food Particles Regulates the Mechanosensing Misshapen-Yorkie Pathway in Drosophila Intestinal Growth by Li, Qi, Nirala, Niraj K., Nie, Yingchao, Chen, Hsi-Ju, Ostroff, Gary, Mao, Junhao, Wang, Qi, Xu, Lan, Ip, Y. Tony

“…The intestinal epithelium has a high cell turnover rate and is an excellent system to study stem cell-mediated adaptive growth. In the Drosophila midgut, the…”
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A nutrient responsive lipase mediates gut-brain communication to regulate insulin secretion in Drosophila by Singh, Alka, Abhilasha, Kandahalli Venkataranganayaka, Acharya, Kathya R., Liu, Haibo, Nirala, Niraj K., Parthibane, Velayoudame, Kunduri, Govind, Abimannan, Thiruvaimozhi, Tantalla, Jacob, Zhu, Lihua Julie, Acharya, Jairaj K., Acharya, Usha R.

“…Pancreatic β cells secrete insulin in response to glucose elevation to maintain glucose homeostasis. A complex network of inter-organ communication operates to…”
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dagLogo: An R/Bioconductor package for identifying and visualizing differential amino acid group usage in proteomics data by Ou, Jianhong, Liu, Haibo, Nirala, Niraj K, Stukalov, Alexey, Acharya, Usha, Green, Michael R, Zhu, Lihua Julie

“…Sequence logos have been widely used as graphical representations of conserved nucleic acid and protein motifs. Due to the complexity of the amino acid (AA)…”
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The Snakeskin-Mesh Complex of Smooth Septate Junction Restricts Yorkie to Regulate Intestinal Homeostasis in Drosophila by Chen, Hsi-Ju, Li, Qi, Nirala, Niraj K., Ip, Y. Tony

“…Tight junctions in mammals and septate junctions in insects are essential for epithelial integrity. We show here that, in the Drosophila intestine, smooth…”
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Survival response to increased ceramide involves metabolic adaptation through novel regulators of glycolysis and lipolysis by Nirala, Niraj K, Rahman, Motiur, Walls, Stanley M, Singh, Alka, Zhu, Lihua Julie, Bamba, Takeshi, Fukusaki, Eiichiro, Srideshikan, Sargur M, Harris, Greg L, Ip, Y Tony, Bodmer, Rolf, Acharya, Usha R

“…The sphingolipid ceramide elicits several stress responses, however, organisms survive despite increased ceramide but how they do so is poorly understood. We…”
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Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activity by Rahman, Motiur, Nirala, Niraj K, Singh, Alka, Zhu, Lihua Julie, Taguchi, Kaori, Bamba, Takeshi, Fukusaki, Eiichiro, Shaw, Leslie M, Lambright, David G, Acharya, Jairaj K, Acharya, Usha R

“…Adenosine triphosphate (ATP) synthase β, the catalytic subunit of mitochondrial complex V, synthesizes ATP. We show that ATP synthase β is deacetylated by a…”
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Hinfp is a guardian of the somatic genome by repressing transposable elements by Nirala, Niraj K., Li, Qi, Ghule, Prachi N., Chen, Hsi-Ju, Li, Rui, Zhu, Lihua Julie, Wang, Ruijia, Rice, Nicholas P., Mao, Junhao, Stein, Janet L., Stein, Gary S., van Wijnen, Andre J., Ip, Y. Tony

“…Germ cells possess the Piwi-interacting RNA pathway to repress transposable elements and maintain genome stability across generations. Transposable element…”
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Oncogenic Pathways and Loss of the Rab11 GTPase Synergize To Alter Metabolism in Drosophila by Nie, Yingchao, Yu, Shiyan, Li, Qi, Nirala, Niraj K, Amcheslavsky, Alla, Edwards, Yvonne J K, Shum, Patrick W, Jiang, Zhong, Wang, Wei, Zhang, Biliang, Gao, Nan, Ip, Y Tony

“…Colorectal cancer is a complex disease driven by well-established mutations such as APC and other yet to be identified pathways. The GTPase Rab11 regulates…”
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TrpA1 is a shear stress mechanosensing channel regulating intestinal stem cell proliferation in Drosophila by Gong, Jiaxin, Nirala, Niraj K, Chen, Jiazhang, Wang, Fei, Gu, Pengyu, Wen, Qi, Ip, Y Tony, Xiang, Yang

“…Adult stem cells are essential for tissue maintenance and repair. Although genetic pathways for controlling adult stem cells are extensively investigated in…”
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The Misshapen subfamily of Ste20 kinases regulate proliferation in the aging mammalian intestinal epithelium by Li, Qi, Nirala, Niraj K., Chen, Hsi‐Ju, Nie, Yingchao, Wang, Wei, Zhang, Biliang, Czech, Michael P., Wang, Qi, Xu, Lan, Mao, Junhao, Ip, Y. Tony

“…The intestinal epithelium has a high rate of cell turn over and is an excellent system to study stem cell‐mediated tissue homeostasis. The Misshapen subfamily…”
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Sphingosine kinases and their metabolites modulate endolysosomal trafficking in photoreceptors by Yonamine, Ikuko, Bamba, Takeshi, Nirala, Niraj K, Jesmin, Nahid, Kosakowska-Cholody, Teresa, Nagashima, Kunio, Fukusaki, Eiichiro, Acharya, Jairaj K, Acharya, Usha

“…Internalized membrane proteins are either transported to late endosomes and lysosomes for degradation or recycled to the plasma membrane. Although proteins…”
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Drosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase [Beta] and regulates complex V activity by Rahman, Motiur, Nirala, Niraj K, Singh, Alka, Zhu, Lihua Julie, Taguchi, Kaori, Bamba, Takeshi, Fukusaki, Eiichiro, Shaw, Leslie M, Lambright, David G, Acharya, Jairaj K, Acharya, Usha R

“…Adenosine triphosphate (ATP) synthase β, the catalytic subunit of mitochondrial complex V, synthesizes ATP. We show that ATP synthase β is deacetylated by a…”
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Oncogenic Pathways and Loss of the Rab11 GTPase Synergize To Alter Metabolism in Drosophila by Nie, Yingchao, Yu, Shiyan, Li, Qi, Nirala, Niraj K, Amcheslavsky, Alla, Edwards, Yvonne J K, Shum, Patrick W, Jiang, Zhong, Wang, Wei, Zhang, Biliang, Gao, Nan, Ip, Y Tony

“…Colorectal cancer is a complex disease driven by well-established mutations such as APC and other yet to be identified pathways. The GTPase Rab11 regulates…”
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Overexpression of odc (ornithine decarboxylase) in Datura innoxia enhances the yield of scopolamine by Singh, Alka, Nirala, Niraj K., Das, Sandip, Narula, Alka, Rajam, M. V., Srivastava, P. S.

“…Scopolamine is widely used for its anticholinergic properties. Because of higher physiological activity and less side effects the world demand of scopolamine…”
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Survival Response to Increased Ceramide Involves Metabolic Adaptation through Novel Regulators of Glycolysis and Lipolysis: e1003556 by Nirala, Niraj K, Rahman, Motiur, Walls, Stanley M, Singh, Alka, Zhu, Lihua Julie, Bamba, Takeshi, Fukusaki, Eiichiro, Srideshikan, Sargur M, Harris, Greg L, Ip, Y Tony, Bodmer, Rolf, Acharya, Usha R

“…The sphingolipid ceramide elicits several stress responses, however, organisms survive despite increased ceramide but how they do so is poorly understood. We…”
Get full text