Search Results - "Niogret, Julie"

Follicular helper-T cells restore CD8+-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy by Niogret, Julie, Berger, Hélène, Rebe, Cédric, Mary, Romain, Ballot, Elise, Truntzer, Caroline, Thibaudin, Marion, Derangère, Valentin, Hibos, Christophe, Hampe, Léa, Rageot, David, Accogli, Théo, Joubert, Philippe, Routy, Bertrand, Harker, James, Vegran, Frederique, Ghiringhelli, Francois, Chalmin, Fanny

“…BackgroundT follicular helper cells (Tfh) are essential to shape B cell response during germinal center formation. Tfh accumulation has been reported in…”
Get full text

Is There a Role for Large Exome Sequencing in the Management of Metastatic Non-Small Cell Lung Cancer: A Brief Report of Real Life by Dalens, Lorraine, Niogret, Julie, Kaderbhai, Courèche Guillaume, Boidot, Romain

“…Non-small-cell lung cancer (NSCLC) is one of the main causes of death by cancer worldwide. With the rise of targeted therapies, the search for molecular…”
Get full text

Durable response of lung carcinoma patients to EGFR tyrosine kinase inhibitors is determined by germline polymorphisms in some immune-related genes by Dalens, Lorraine, Niogret, Julie, Richard, Corentin, Chevrier, Sandy, Foucher, Pascal, Coudert, Bruno, Lagrange, Aurélie, Favier, Laure, Westeel, Virginie, Kim, Stefano, Adotevi, Olivier, Chapusot, Caroline, Martin, Laurent, Arnould, Laurent, Kaderbhai, Courèche-Guillaume, Boidot, Romain

“…Non-small cell lung cancer is a very poor prognosis disease. Molecular analyses have highlighted several genetic alterations which may be targeted by specific…”
Get full text

Association of Anti-EGFR Antibody and MEK Inhibitor in Gynecological Cancer Harboring RAS Mutation: A Case Series by Niogret, Julie, Derangère, Valentin, Richard, Corentin, Nuttin, Lisa, Ghiringhelli, François, Favier, Laure, Lefevre, Leila Bengrine, Bergeron, Anthony, Arnould, Laurent, Boidot, Romain

“…Low-grade serous carcinoma represents a minority of serous carcinoma. Although they have better prognosis than high-grade serous carcinoma, they respond poorly…”
Get full text

Improving olaparib exposure to optimize adverse effects management by Sterlé, Marylise, Puszkiel, Alicja, Burlot, Chloé, Pereira, Eva, Bellesoeur, Audrey, De Percin, Sixtine, Beinse, Guillaume, Fumet, Jean-David, Favier, Laure, Niogret, Julie, Blanchet, Benoit, Royer, Bernard, Bengrine-Lefevre, Leïla, Schmitt, Antonin

“…Olaparib is an inhibitor of the human poly-(ADP-ribose)-polymerase enzymes (PARP1/2) needed to repair single-strand DNA breaks. It is used in breast, ovarian,…”
Get full text

Implementation and use of whole exome sequencing for metastatic solid cancer by Réda, Manon, Richard, Corentin, Bertaut, Aurelie, Niogret, Julie, Collot, Thomas, Fumet, Jean David, Blanc, Julie, Truntzer, Caroline, Desmoulins, Isabelle, Ladoire, Sylvain, Hennequin, Audrey, Favier, Laure, Bengrine, Leila, Vincent, Julie, Hervieu, Alice, Dusserre, Jean-Florian Guion, Lepage, Come, Foucher, Pascal, Borg, Christophe, Albuisson, Juliette, Arnould, Laurent, Nambot, Sophie, Faivre, Laurence, Boidot, Romain, Ghiringhelli, Francois

“…Genomically-guided clinical trials are performed across different tumor types sharing genetic mutations, but trial organization remains complex. Here we…”
Get full text

Primary Resistance to Afatinib in a Patient with Lung Adenocarcinoma Harboring Uncommon EGFR Mutations: S768I and V769L by Niogret, Julie, Coudert, Bruno, Boidot, Romain

Get more information

Associated Factors to Efficacy and Tolerance of Immunotherapy in Older Patients with Cancer Aged 70 Years and Over: Impact of Coprescriptions by Perret, Marie, Bertaut, Aurélie, Niogret, Julie, Marilier, Sophie, Jouanny, Pierre, Manckoundia, Patrick, Bengrine-Lefevre, Leïla, Quipourt, Valérie, Barben, Jérémy

“…Background Immunotherapy with immune checkpoint blockers (ICB) significantly improves the prognosis for an increasing number of cancers. However, data on…”
Get full text

The challenge of ovarian cancer care in the oldest old by Barben, Jérémy, Galvin, Angéline, Kamga, Ariane Mamguem, Bertrand, Nicolas, Niogret, Julie, Tisserand, Julie, Quipourt, Valérie, Bengrine-Lefevre, Leila, Dabakuyo-Yonli, Tienhan Sandrine

“…Ovarian cancer (OC) is the eighth most common cancer in women, with a poor prognosis, particularly in older women. The aim of this study was to describe an…”
Get full text

Phase II of desynchronized irinotecan plus bevacizumab, oxaliplatin, 5-fluorouracil, and folinic acid (bFOLFIRINOX-3) administration in chemorefractory metastatic colorectal cancer patients by Fumet, Jean-David, Bertaut, Aurelie, Roussot, Nicolas, Bellio, Hélène, Bengrine-Lefevre, Leila, Vincent, Julie, Niogret, Julie, Palmier, Rémi, Collot, Thomas, Rambach, Laurie, Boudrant, Axelle, Parnalland, Sophie, Rederstorff, Emilie, Hennequin, Audrey, Zanetta, Sylvie, Hervieu, Alice, Ghiringhelli, François

“…e15563 Background: In chemorefractory metastatic colorectal cancer (mCRC), targeted therapy such as TAS-102 and regorafenib have shown a modest survival…”
Get full text

PARP inhibitor resistance and TP53 mutations in patients treated with olaparib for BRCA-mutated cancer: Four case reports by Collot, Thomas, Niogret, Julie, Carnet, Marion, Chevrier, Sandy, Humblin, Etienne, Favier, Laure, Bengrine-Lefevre, Leila, Desmoulins, Isabelle, Arnould, Laurent, Boidot, Romain

“…Loss‑of‑function BRCA mutations are frequent in high‑grade serous ovarian carcinoma. BRCA1 and ‑2 mutations lead to homologous recombination (HR) deficiency…”
Get full text

Carboplatin and Etoposide for the Treatment of Metastatic Prostate Cancer with or without Neuroendocrine Features: A French Single-Center Experience by Baude, Jérémy, Niogret, Julie, Jacob, Pierre, Bardet, Florian, Desmoulins, Isabelle, Zanetta, Sylvie, Kaderbhai, Courèche, Galland, Loïck, Mayeur, Didier, Delattre, Benjamin, Cormier, Luc, Ladoire, Sylvain

“…Chemotherapy using carboplatin and etoposide (CE) is frequently pragmatically proposed to treat metastatic prostate cancer (mPC), both primary small-cell…”
Get full text

Does large NGS panel analysed using exome tumour sequencing improve the management of advanced non-small-cell lung cancers? by Niogret, Julie, Dalens, Lorraine, Truntzer, Caroline, Chevrier, Sandy, Favier, Laure, Lagrange, Aurélie, Coudert, Bruno, Fraisse, Cléa, Foucher, Pascal, Zouak, Ayoub, Westeel, Virginie, Goussot, Vincent, Dérangère, Valentin, Albuisson, Juliette, Arnould, Laurent, Boidot, Romain, Kaderbhai, Courèche-Guillaume, Ghiringhelli, François

“…•Large Next Generation Sequencing (LNGS) is feasible in routine practice.•LNGS identified at least one potential molecular target in 74.4% of patients.•LNGS do…”
Get full text

EGFR amplification induces sensitivity to antiEGFR therapy in pancreatic acinar cell carcinoma by Richard, Corentin, Niogret, Julie, Boidot, Romain, Ghiringhelli, Francois

“…Pancreatic acinar cell carcinoma (PACC) is a rare cancer. When the tumor is metastatic, few therapeutic options are available. Precision medicine using…”
Get full text

EGFR amplification induces sensitivity to anti EGFR therapy in pancreatic acinar cell carcinoma by Richard, Corentin, Niogret, Julie, Boidot, Romain, Ghiringhelli, Francois

“…Pancreatic acinar cell carcinoma (PACC) is a rare cancer. When the tumor is metastatic, few therapeutic options are available. Precision medicine using…”
Get full text

Baseline Splenic Volume as a Prognostic Biomarker of FOLFIRI Efficacy and a Surrogate Marker of MDSC Accumulation in Metastatic Colorectal Carcinoma by Niogret, Julie, Limagne, Emeric, Thibaudin, Marion, Blanc, Julie, Bertaut, Aurelie, Le Malicot, Karine, Rinaldi, Yves, Caroli-Bosc, François-Xavier, Audemar, Franck, Nguyen, Suzanne, Sarda, Corinne, Lombard-Bohas, Catherine, Locher, Christophe, Carreiro, Miguel, Legoux, Jean-Louis, Etienne, Pierre-Luc, Baconnier, Mathieu, Porneuf, Marc, Aparicio, Thomas, Ghiringhelli, Francois

“…Background: Predictive biomarkers of response to chemotherapy plus antiangiogenic for metastatic colorectal cancer (mCRC) are lacking. The objective of this…”
Get full text

Association of Anti-EGFR Antibody and MEK Inhibitor in Gynecological Cancer Harboring RAS Mutation: A Case Series by Niogret, Julie, Derangère, Valentin, Richard, Corentin, Nuttin, Lisa, Ghiringhelli, François, Favier, Laure, Lefevre, Leila Bengrine, Bergeron, Anthony, Arnould, Laurent, Boidot, Romain

Get full text

EGFR amplification induces sensitivity to antiEGFR therapy in pancreatic acinar cell carcinoma by Richard, Corentin, Niogret, Julie, Boidot, Romain, Ghiringhelli, Francois

Get full text