Search Results - "Ninomiya, Yasuharu"
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Radiation-Induced Reactions in The Liver - Modulation of Radiation Effects by Lifestyle-Related Factors
Published in International journal of molecular sciences (03-12-2018)“…Radiation has a wide variety of effects on the liver. Fibrosis is a concern in medical fields as one of the acute effects of high-dose irradiation, such as…”
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Impacts of psychological stress on high dose-rate radiation acute effects in a mouse experimental model
Published in Journal of radiation research (19-07-2022)“…Abstract Psychological stress affects health. Radiation workers in the medical field or astronauts living in space have possible risks of exposure to…”
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ROS stress resets circadian clocks to coordinate pro-survival signals
Published in PloS one (02-12-2013)“…Dysfunction of circadian clocks exacerbates various diseases, in part likely due to impaired stress resistance. It is unclear how circadian clock system…”
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Cooperative interaction among BMAL1, HSF1, and p53 protects mammalian cells from UV stress
Published in Communications biology (22-11-2018)“…The circadian clock allows physiological systems to adapt to their changing environment by synchronizing their timings in response to external stimuli…”
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Reduced High-Dose Radiation-Induced Residual Genotoxic Damage by Induction of Radioadaptive Response and Prophylactic Mild Dietary Restriction in Mice
Published in Dose-response (01-01-2021)“…Radioadaptive response (RAR) describes a phenomenon in a variety of in vitro and in vivo systems that a low-dose of priming ionizing radiation (IR) reduces…”
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Fluorescence in situ hybridization analysis of chromosomal aberrations in mouse splenocytes at one- and two-months after total body exposure to iron-56 (Fe) ion particles or X-rays
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01-10-2022)Get full text
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Synergistic Effects of Chronic Restraint-Induced Stress and Low-Dose 56Fe-particle Irradiation on Induction of Chromosomal Aberrations in Trp53-Heterozygous Mice
Published in Radiation research (26-04-2021)“…Astronauts can develop psychological stress (PS) during space flights due to the enclosed environment, microgravity, altered light-dark cycles, and risks of…”
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Diallyl Disulfide Mitigates DNA Damage and Spleen Tissue Effects After Irradiation
Published in Medical science monitor (24-11-2019)“…BACKGROUND Several factors found in foods are beneficial to human health and they may contribute to radiation protection. Taking food factors could be an easy…”
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Enhanced Effects of Chronic Restraint-Induced Psychological Stress on Total Body Fe-Irradiation-Induced Hematopoietic Toxicity in Trp53 -Heterozygous Mice
Published in Life (Basel, Switzerland) (10-04-2022)“…Humans are exposed to both psychological stress (PS) and radiation in some scenarios such as manned deep-space missions. It is of great concern to verify…”
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Increased Hematopoietic Stem Cells/Hematopoietic Progenitor Cells Measured as Endogenous Spleen Colonies in Radiation-Induced Adaptive Response in Mice (Yonezawa Effect)
Published in Dose-response (20-08-2018)“…The existence of radiation-induced adaptive response (AR) was reported in varied biosystems. In mice, the first in vivo AR model was established using X-rays…”
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Altered Response to Total Body Irradiation of C57BL/6-Tg (CAG-EGFP) Mice
Published in Dose-response (01-07-2020)“…Application of green fluorescent protein (GFP) in a variety of biosystems as a unique bioindicator or biomarker has revolutionized biological research and made…”
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More efficient induction of genotoxicity by high-LET Fe-particle radiation than low-LET X-ray radiation at low doses
Published in Radiation medicine and protection (01-03-2023)“…To understand differential effects on induction of genotoxicity and genomic instability (GI) by high-LET particle radiation and low-LET photon radiation, based…”
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Total body 100-mGy X-irradiation does not induce Alzheimer's disease-like pathogenesis or memory impairment in mice
Published in Journal of radiation research (01-01-2014)“…The cause and progression of Alzheimer's disease (AD) are poorly understood. Possible cognitive and behavioral consequences induced by low-dose radiation are…”
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Sodium orthovanadate (vanadate), a potent mitigator of radiation-induced damage to the hematopoietic system in mice
Published in Journal of radiation research (01-07-2013)“…Previous in vitro and in vivo studies have shown that sodium orthovanadate (vanadate), an inorganic vanadium compound, could effectively suppress…”
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Effects of chronic restraint-induced stress on radiation-induced chromosomal aberrations in mouse splenocytes
Published in Mutation research (01-01-2017)“…•Combined effects of psychological stress and X-rays on wild type mice were analysed.•Either psychological stress or X-rays reduced the number of…”
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Arsenite induces premature senescence via p53/p21 pathway as a result of DNA damage in human malignant glioblastoma cells
Published in BMB reports (01-10-2014)“…In this study, we investigate whether arsenite-induced DNA damage leads to p53-dependent premature senescence using human glioblastoma cells with p53-wild type…”
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Low-dose total-body carbon-ion irradiations induce early transcriptional alteration without late Alzheimer's disease-like pathogenesis and memory impairment in mice
Published in Journal of neuroscience research (01-07-2014)“…The cause and risk factors of Alzheimer's disease (AD) are largely unknown. Studies on possible radiation‐induced AD‐like pathogenesis and behavioral…”
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Chronic restraint-induced stress has little modifying effect on radiation hematopoietic toxicity in mice
Published in Journal of radiation research (01-09-2015)“…Both radiation and stresses cause detrimental effects on humans. Besides possible health effects resulting directly from radiation exposure, the nuclear plant…”
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Characterization of Ninjurin and TSC22 induction after X-irradiation of normal human skin cells
Published in Journal of dermatology (01-01-2008)“…ABSTRACT The skin is an external organ that is most frequently exposed to radiation. It is important to elucidate the influence of radiation exposure on the…”
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X-Ray-Induced Radioresistance against High-LET Radiations from Accelerated Heavy Ions in Mice
Published in Radiation research (01-10-2010)“…Induction of an adaptive response by priming X rays in combination with challenge irradiations from high-LET accelerated heavy ions was attempted in young…”
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