Search Results - "Ninnemann, Olaf"

Sirt1 contributes critically to the redox-dependent fate of neural progenitors by Aktas, Orhan, Glumm, Robert, Baumgart, Jan, Schröter, Friederike, Siegert, Elise, Bendix, Ivo, Schulze-Topphoff, Ulf, Nitsch, Robert, Prozorovski, Timour, Ninnemann, Olaf, Zipp, Frauke, Brüstle, Oliver

“…Repair processes that are activated in response to neuronal injury, be it inflammatory, ischaemic, metabolic, traumatic or other cause, are characterized by a…”
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Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation by Ravindran, Ethiraj, Hu, Hao, Yuzwa, Scott A, Hernandez-Miranda, Luis R, Kraemer, Nadine, Ninnemann, Olaf, Musante, Luciana, Boltshauser, Eugen, Schindler, Detlev, Hübner, Angela, Reinecker, Hans-Christian, Ropers, Hans-Hilger, Birchmeier, Carmen, Miller, Freda D, Wienker, Thomas F, Hübner, Christoph, Kaindl, Angela M

“…Mid-hindbrain malformations can occur during embryogenesis through a disturbance of transient and localized gene expression patterns within these distinct…”
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Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling by Cheng, Jin, Sahani, Sadhna, Hausrat, Torben Johann, Yang, Jenq-Wei, Ji, Haichao, Schmarowski, Nikolai, Endle, Heiko, Liu, Xinfeng, Li, Yunbo, Böttche, Rahel, Radyushkin, Konstantin, Maric, Hans M., Hoerder-Suabedissen, Anna, Molnár, Zoltán, Prouvot, Pierre-Hugues, Trimbuch, Thorsten, Ninnemann, Olaf, Huai, Jisen, Fan, Wei, Visentin, Barbara, Sabbadini, Roger, Strømgaard, Kristian, Stroh, Albrecht, Luhmann, Heiko J., Kneussel, Matthias, Nitsch, Robert, Vogt, Johannes

“…Precise connection of thalamic barreloids with their corresponding cortical barrels is critical for processing of vibrissal sensory information. Here, we show…”
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Novel Alternative Splice Variants of Mouse Cdk5rap2 by Kraemer, Nadine, Issa-Jahns, Lina, Neubert, Gerda, Ravindran, Ethiraj, Mani, Shyamala, Ninnemann, Olaf, Kaindl, Angela M

“…Autosomal recessive primary microcephaly (MCPH) is a rare neurodevelopmental disorder characterized by a pronounced reduction of brain volume and intellectual…”
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Comparative analysis of uncoupling protein 4 distribution in various tissues under physiological conditions and during development by Smorodchenko, Alina, Rupprecht, Anne, Sarilova, Irina, Ninnemann, Olaf, Bräuer, Anja U., Franke, Kristin, Schumacher, Stefan, Techritz, Sandra, Nitsch, Robert, Schuelke, Markus, Pohl, Elena E.

“…UCP4 is a member of the mitochondrial uncoupling protein subfamily and one of the three UCPs (UCP2, UCP4, UCP5), associated with the nervous system. Its…”
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A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting by Nitsch, Robert, Bräuer, Anja U, Savaskan, Nicolai E, Kühn, Hartmut, Prehn, Siegfried, Ninnemann, Olaf

“…Outgrowth of axons in the central nervous system is governed by specific molecular cues. Molecules detected so far act as ligands that bind to specific…”
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Differential regulation of three functional ammonium transporter genes by nitrogen in root hairs and by light in leaves of tomato by Von Wirén, Nicolaus, Lauter, Frank‐Roman, Ninnemann, Olaf, Gillissen, Bernd, Walch‐Liu, Pia, Engels, Christof, Jost, Wolfgang, Frommer, Wolf B.

“…Summary To elucidate the role of transporters in N nutrition of tomato, two new transporter genes were isolated from cDNA libraries of root hairs or leaves of…”
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Selenium deficiency increases susceptibility to glutamate‐induced excitotoxicity by Savaskan, Nicolai E., Bräuer, Anja U., Kühbacher, Markus, Eyüpoglu, Ilker Y., Kyriakopoulos, Antonios, Ninnemann, Olaf, Behne, Dietrich, Nitsch, Robert

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A Role for the Eph Ligand Ephrin-A3 in Entorhino-Hippocampal Axon Targeting by Stein, Eckart, Savaskan, Nicolai E, Ninnemann, Olaf, Nitsch, Robert, Zhou, Renping, Skutella, Thomas

“…Neurons of layers II and III of the entorhinal cortex constitute the major afferent connection of the hippocampus. The molecular mechanisms that target the…”
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Macrophage/microglia activation factor expression is restricted to lesion-associated microglial cells after brain trauma by Lünemann, Anna, Ullrich, Oliver, Diestel, Antje, Jöns, Thomas, Ninnemann, Olaf, Kovac, Adam, Pohl, Elena E., Hass, Ralf, Nitsch, Robert, Hendrix, Sven

“…After traumatic brain lesion, microglial cells are rapidly activated, migrate toward the sites of injury, and cause secondary damage that accounts for most of…”
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Sema3C and Netrin-1 Differentially Affect Axon Growth in the Hippocampal Formation by Steup, Andreas, Lohrum, Marion, Hamscho, Nadja, Savaskan, Nicolai E., Ninnemann, Olaf, Nitsch, Robert, Fujisawa, Hajime, Püschel, Andreas W., Skutella, Thomas

“…The interaction between outgrowing neurons and their targets is a central element in the development of the afferent and efferent connections of the…”
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Seed and vascular expression of a high-affinity transporter for cationic amino acids in Arabidopsis by Frommer, W.B. (Institut fur Genbiologische Forschung, Berlin, Germany.), Hummel, S, Unseld, M, Ninnemann, O

“…In most plants amino acids represent the major transport form for organic nitrogen. A sensitive selection system in yeast mutants has allowed identification of…”
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Semaphorin D acts as a repulsive factor for entorhinal and hippocampal neurons by Steup, Andreas, Ninnemann, Olaf, Savaskan, Nicolai E., Püschel, Robert Nitsch andreas W., Skutella, Thomas

“…We analysed the effects of semaphorin D on axons from the developing rat entorhinal–hippocampal formation. Explants from superficial layers of the entorhinal…”
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An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration by Lehmann, Sabrina M, Krüger, Christina, Park, Boyoun, Derkow, Katja, Rosenberger, Karen, Baumgart, Jan, Trimbuch, Thorsten, Eom, Gina, Hinz, Michael, Kaul, David, Habbel, Piet, Kälin, Roland, Franzoni, Eleonora, Rybak, Agnieszka, Nguyen, Duong, Veh, Rüdiger, Ninnemann, Olaf, Peters, Oliver, Nitsch, Robert, Heppner, Frank L, Golenbock, Douglas, Schott, Eckart, Ploegh, Hidde L, Wulczyn, F Gregory, Lehnardt, Seija

“…In addition to their function in gene regulation, certain microRNAs can be secreted by cells. Here, the authors show that the microRNA let-7 can cause…”
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PTRH2 is Necessary for Purkinje Cell Differentiation and Survival and its Loss Recapitulates Progressive Cerebellar Atrophy and Ataxia Seen in IMNEPD Patients by Picker-Minh, Sylvie, Luperi, Ilaria, Ravindran, Ethiraj, Kraemer, Nadine, Zaqout, Sami, Stoltenburg-Didinger, Gisela, Ninnemann, Olaf, Hernandez-Miranda, Luis R., Mani, Shyamala, Kaindl, Angela M.

“…Hom ozygous variants in the peptidyl-tRNA hydrolase 2 gene ( PTRH2 ) cause infantile-onset multisystem neurologic, endocrine, and pancreatic disease. The…”
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Post-transcriptional regulation of the let-7 microRNA during neural cell specification by Wulczyn, F. Gregory, Smirnova, Lena, Rybak, Agnieszka, Brandt, Christine, Kwidzinski, Erik, Ninnemann, Olaf, Strehle, Michael, Seiler, Andrea, Schumacher, Stefan, Nitsch, Robert

“…The let-7 miRNA regulates developmental timing in C. elegans and is an important paradigm for investigations of miRNA functions in mammalian development. We…”
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Togaram1 is expressed in the neural tube and its absence causes neural tube closure defects by Wang, Yanyan, Kraemer, Nadine, Schneider, Joanna, Ninnemann, Olaf, Weng, Kai, Hildebrand, Michael, Reid, Joshua, Li, Na, Hu, Hao, Mani, Shyamala, Kaindl, Angela M.

“…Neural tube closure defect pathomechanisms in human embryonic development are poorly understood. Here we identified spina bifida patients expressing novel…”
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CDK5RAP2 expression during murine and human brain development correlates with pathology in primary autosomal recessive microcephaly by Issa, Lina, Kraemer, Nadine, Rickert, Christian H, Sifringer, Marco, Ninnemann, Olaf, Stoltenburg-Didinger, Gisela, Kaindl, Angela M

“…Homozygous mutations in the cyclin-dependent kinase-5 regulatory subunit-associated protein 2 gene CDK5RAP2 cause primary autosomal recessive microcephaly…”
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Role of the Transmembrane Potential in the Membrane Proton Leak by Rupprecht, Anne, Sokolenko, Elena A., Beck, Valeri, Ninnemann, Olaf, Jaburek, Martin, Trimbuch, Thorsten, Klishin, Sergey S., Jezek, Petr, Skulachev, Vladimir P., Pohl, Elena E.

“…The molecular mechanism responsible for the regulation of the mitochondrial membrane proton conductance (G) is not clearly understood. This study investigates…”
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PRG-1 transcriptional regulation independent from Nex1/Math2-mediated activation by Geist, Beate, Vorwerk, Brita, Coiro, Pierluca, Ninnemann, Olaf, Nitsch, Robert

“…Plasticity-related gene 1 (PRG-1) is a novel player in glutamatergic synaptic transmission, acting by interfering with lysophosphatidic acid (LPA)-dependent…”
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