Search Results - "Ningoo, Mehek"

PIP2 regulation of TRPC5 channel activation and desensitization by Ningoo, Mehek, Plant, Leigh D., Greka, Anna, Logothetis, Diomedes E.

“…Transient receptor potential canonical type 5 (TRPC5) ion channels are expressed in the brain and kidney and have been identified as promising therapeutic…”
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Small-molecule TIP60 inhibitors enhance regulatory T cell induction through TIP60-P300 acetylation crosstalk by Fueyo-González, Francisco, Vilanova, Guillermo, Ningoo, Mehek, Marjanovic, Nada, González-Vera, Juan A., Orte, Ángel, Fribourg, Miguel

“…Foxp3 acetylation is essential to regulatory T (Treg) cell stability and function, but pharmacologically increasing it remains an unmet challenge. Here, we…”
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From stem cells to regulatory T cells: A tale of plasticity by Ningoo, Mehek, Fribourg, Miguel

“…In this issue, Yano et al. present a method to obtain suppressive regulatory T (Treg) cells from human induced pluripotent stem cells (hiPSCs). This approach…”
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T-cell receptor sequencing reveals selected donor-reactive CD8+ T cell clones resist antithymocyte globulin depletion after kidney transplantation by Ningoo, Mehek, Cruz-Encarnación, Pamela, Khilnani, Calla, Heeger, Peter S., Fribourg, Miguel

“…High frequencies of donor-reactive memory T cells in the periphery of transplant candidates prior to transplantation are linked to the development of…”
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Interferon-β acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation by Fueyo-González, Francisco, McGinty, Mitchell, Ningoo, Mehek, Anderson, Lisa, Cantarelli, Chiara, Andrea Angeletti, Demir, Markus, Llaudó, Inés, Purroy, Carolina, Marjanovic, Nada, Heja, David, Sealfon, Stuart C., Heeger, Peter S., Cravedi, Paolo, Fribourg, Miguel

“…Type I interferons (IFNs) are pleiotropic cytokines with potent antiviral properties that also promote protective T cell and humoral immunity. Paradoxically,…”
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PIP 2 regulation of TRPC5 channel activation and desensitization by Ningoo, Mehek, Plant, Leigh D, Greka, Anna, Logothetis, Diomedes E

“…Transient receptor potential canonical type 5 (TRPC5) ion channels are expressed in the brain and kidney, and have been identified as promising therapeutic…”
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Role of PIP2 in PLC-Mediated Activation and Desensitization of TRPC5 Channels by Ningoo, Mehek Sameer

“…Progressive kidney diseases affect more than 750 million people worldwide. Focal segmental glomerular sclerosis (FSGS) is a leading progressive chronic kidney…”
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